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The map label for this gene is nudL [H]

Identifier: 220915297

GI number: 220915297

Start: 193649

End: 194239

Strand: Direct

Name: nudL [H]

Synonym: A2cp1_0176

Alternate gene names: 220915297

Gene position: 193649-194239 (Clockwise)

Preceding gene: 220915296

Following gene: 220915298

Centisome position: 3.85

GC content: 73.27

Gene sequence:

>591_bases
GTGACGCTCGACGATCTCGCCGCGGCGCTGGTCGCCCGCGAGCCGGGGATCGCCCCGGTGGACCGGATCGCGCAGGAGCA
CCTGCCCCGCGGCGGCTTCGCGTCGGCGGCGGTGCTGGTGCCGCTGCACGTGCTCGACGGCGAGGTGCACGTGCTCATGA
TCCGCCGGCCGATGAAGATGTCCCGCCACGCGGGGCAGATCGCCTTCCCCGGCGGCAAGATCGACCCGGGGGAGGAGAGC
CTCGCCGCCGCGCTGCGCGAGGCGCACGAGGAGGTGGGGCTCGAGCCGGCGCGCGCCGACGTCATGGGACAGCTCAGCGA
GACGCTGGTGCTCGCGTCGGCCTTCCGCTTGACGCCGTGGGTGGCTTCCGTGCCATATCCCTACCCGTACGCGGCCGCGC
CGCACGAGGTGGACGAGATCCTGCACGTCCCGCTCTCGGCGCTCTCCCGCCCCGGCGCGCACCGGGTCGAGTGGCGCGAG
GTCTACGGCCTGAGGCTCGACGTGCACTTCTTCTCGGTCGGCAAGGACGTGATCTGGGGCGCGACGGGTCGCGTGCTCGC
CGAGCTCCTGTCCATCTGGAGGGCGTCGTGA

Upstream 100 bases:

>100_bases
TCGCCGCCGGCGCCGCCATCGCGGCGCTCATCCTCTCCGGCGTCCTCCCCGCCGGCGCCGAGGCGCCCCCGCCGCCTCCG
CCGGCCCTGCACGCGGCCCC

Downstream 100 bases:

>100_bases
AGATCTACCCGGTGATCATGGCGGGCGGCTCGGGCACGCGGTTCTGGCCGCTGTCGCGCCGCAACCGCCCGAAGCAGTTC
CTGGCGCTCGCCGGCGACGC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTLDDLAAALVAREPGIAPVDRIAQEHLPRGGFASAAVLVPLHVLDGEVHVLMIRRPMKMSRHAGQIAFPGGKIDPGEES
LAAALREAHEEVGLEPARADVMGQLSETLVLASAFRLTPWVASVPYPYPYAAAPHEVDEILHVPLSALSRPGAHRVEWRE
VYGLRLDVHFFSVGKDVIWGATGRVLAELLSIWRAS

Sequences:

>Translated_196_residues
MTLDDLAAALVAREPGIAPVDRIAQEHLPRGGFASAAVLVPLHVLDGEVHVLMIRRPMKMSRHAGQIAFPGGKIDPGEES
LAAALREAHEEVGLEPARADVMGQLSETLVLASAFRLTPWVASVPYPYPYAAAPHEVDEILHVPLSALSRPGAHRVEWRE
VYGLRLDVHFFSVGKDVIWGATGRVLAELLSIWRAS
>Mature_195_residues
TLDDLAAALVAREPGIAPVDRIAQEHLPRGGFASAAVLVPLHVLDGEVHVLMIRRPMKMSRHAGQIAFPGGKIDPGEESL
AAALREAHEEVGLEPARADVMGQLSETLVLASAFRLTPWVASVPYPYPYAAAPHEVDEILHVPLSALSRPGAHRVEWREV
YGLRLDVHFFSVGKDVIWGATGRVLAELLSIWRAS

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=146, Percent_Identity=34.9315068493151, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17536993, Length=172, Percent_Identity=27.3255813953488, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 21282; Mature: 21151

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDDLAAALVAREPGIAPVDRIAQEHLPRGGFASAAVLVPLHVLDGEVHVLMIRRPMKM
CCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHH
SRHAGQIAFPGGKIDPGEESLAAALREAHEEVGLEPARADVMGQLSETLVLASAFRLTPW
HHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCH
VASVPYPYPYAAAPHEVDEILHVPLSALSRPGAHRVEWREVYGLRLDVHFFSVGKDVIWG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEEEEECCCCHHHHC
ATGRVLAELLSIWRAS
CHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLDDLAAALVAREPGIAPVDRIAQEHLPRGGFASAAVLVPLHVLDGEVHVLMIRRPMKM
CHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHH
SRHAGQIAFPGGKIDPGEESLAAALREAHEEVGLEPARADVMGQLSETLVLASAFRLTPW
HHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCH
VASVPYPYPYAAAPHEVDEILHVPLSALSRPGAHRVEWREVYGLRLDVHFFSVGKDVIWG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEEEEECCCCHHHHC
ATGRVLAELLSIWRAS
CHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]