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The map label for this gene is uppP

Identifier: 220915296

GI number: 220915296

Start: 192774

End: 193652

Strand: Direct

Name: uppP

Synonym: A2cp1_0175

Alternate gene names: 220915296

Gene position: 192774-193652 (Clockwise)

Preceding gene: 220915295

Following gene: 220915297

Centisome position: 3.83

GC content: 75.77

Gene sequence:

>879_bases
ATGAGCCTCGTCTCCGCGGCGCTGTTCGGGCTGCTCCAGGCGCTCACCGAGTTCCTCCCGGTGAGCTCCACCGCGCACCT
GCTGGTGTTCGGGGAGCTGCTCGGCCACTCGCTCGACGACCGGCGCTTCCGCGCCTTCGTCACGATCATCCAGGCCGGCA
CCACGCTGGCGGTGCTGGTCTACTTCCGCGCCGACATCGCGCGGCTGGTGGCGGCGGCGGCGCGGGGGCTGGCCCGGGGC
AGGCCGTTCGGGACGCCGGAGGCGCGGCTGGGCTGGTACATCGTGCTCGGCACGGTGCCGGCCGCGCTGGCGGGGAAGCT
GCTCGAGCACCGCATCGAGGCGCTCGGCAACTGGGTCATCGCGGGCTCGCTGGTGGCGCTCGGCCTGGTGCTGCTCGCGG
CCGAGCGCCTGGCCAGCCACCGGCGCCGCGTGGAGGACGTGGGCGCGGGCGACGCGCTCCTCATCGGCGTCGCCCAGGCG
CTGGCGCTCGTGCCGGGCAGCTCGCGCTCCGGCACCACCATCACCGGCGGCATGCTGCTCGGCTTCACCCGCGAGGCGGC
GGCGCGCTTCAGCTTCCTGCTCTCGGTCCCCATCACGCTCGCGGCCGGCGCGTACAAGCTCTGGTCCACCGTCCCGGACC
TGCGGGGCGAGGCGGCCTGGACCGTCGCGACGGTGGTCGGTACCGTGGTGTCCGCCGTGGCCGGCTACCTCGTCATCGAC
TGGCTGCTCGCGTGGCTGCGGACGCGCACCACCTACGTGTTCGTGGTCTGGCGGCTCGCCGCCGGCGCCGCCATCGCGGC
GCTCATCCTCTCCGGCGTCCTCCCCGCCGGCGCCGAGGCGCCCCCGCCGCCTCCGCCGGCCCTGCACGCGGCCCCGTGA

Upstream 100 bases:

>100_bases
CCGCCTGACGAAGCTCACCAAGAAGCAGGCGGCCTACATCGGCGTGCCGCAGTCCGGCCCGTTCAAGCCCGACCACTACC
GCTACTAGGCCGGGCGGACG

Downstream 100 bases:

>100_bases
CGCTCGACGATCTCGCCGCGGCGCTGGTCGCCCGCGAGCCGGGGATCGCCCCGGTGGACCGGATCGCGCAGGAGCACCTG
CCCCGCGGCGGCTTCGCGTC

Product: Undecaprenyl-diphosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSLVSAALFGLLQALTEFLPVSSTAHLLVFGELLGHSLDDRRFRAFVTIIQAGTTLAVLVYFRADIARLVAAAARGLARG
RPFGTPEARLGWYIVLGTVPAALAGKLLEHRIEALGNWVIAGSLVALGLVLLAAERLASHRRRVEDVGAGDALLIGVAQA
LALVPGSSRSGTTITGGMLLGFTREAAARFSFLLSVPITLAAGAYKLWSTVPDLRGEAAWTVATVVGTVVSAVAGYLVID
WLLAWLRTRTTYVFVVWRLAAGAAIAALILSGVLPAGAEAPPPPPPALHAAP

Sequences:

>Translated_292_residues
MSLVSAALFGLLQALTEFLPVSSTAHLLVFGELLGHSLDDRRFRAFVTIIQAGTTLAVLVYFRADIARLVAAAARGLARG
RPFGTPEARLGWYIVLGTVPAALAGKLLEHRIEALGNWVIAGSLVALGLVLLAAERLASHRRRVEDVGAGDALLIGVAQA
LALVPGSSRSGTTITGGMLLGFTREAAARFSFLLSVPITLAAGAYKLWSTVPDLRGEAAWTVATVVGTVVSAVAGYLVID
WLLAWLRTRTTYVFVVWRLAAGAAIAALILSGVLPAGAEAPPPPPPALHAAP
>Mature_291_residues
SLVSAALFGLLQALTEFLPVSSTAHLLVFGELLGHSLDDRRFRAFVTIIQAGTTLAVLVYFRADIARLVAAAARGLARGR
PFGTPEARLGWYIVLGTVPAALAGKLLEHRIEALGNWVIAGSLVALGLVLLAAERLASHRRRVEDVGAGDALLIGVAQAL
ALVPGSSRSGTTITGGMLLGFTREAAARFSFLLSVPITLAAGAYKLWSTVPDLRGEAAWTVATVVGTVVSAVAGYLVIDW
LLAWLRTRTTYVFVVWRLAAGAAIAALILSGVLPAGAEAPPPPPPALHAAP

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=272, Percent_Identity=37.8676470588235, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_ANAD2 (B8J8T6)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002490600.1
- GeneID:   7298410
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_0175
- HOGENOM:   HBG391969
- ProtClustDB:   CLSK944863
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30436; Mature: 30305

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x172809f8)-; HASH(0x198c3e84)-; HASH(0x19d1a16c)-; HASH(0x19d0f424)-; HASH(0x1949c178)-; HASH(0x14ce5fbc)-; HASH(0x19d0f388)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVSAALFGLLQALTEFLPVSSTAHLLVFGELLGHSLDDRRFRAFVTIIQAGTTLAVLV
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHH
YFRADIARLVAAAARGLARGRPFGTPEARLGWYIVLGTVPAALAGKLLEHRIEALGNWVI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
AGSLVALGLVLLAAERLASHRRRVEDVGAGDALLIGVAQALALVPGSSRSGTTITGGMLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEECHHHH
GFTREAAARFSFLLSVPITLAAGAYKLWSTVPDLRGEAAWTVATVVGTVVSAVAGYLVID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WLLAWLRTRTTYVFVVWRLAAGAAIAALILSGVLPAGAEAPPPPPPALHAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
SLVSAALFGLLQALTEFLPVSSTAHLLVFGELLGHSLDDRRFRAFVTIIQAGTTLAVLV
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHH
YFRADIARLVAAAARGLARGRPFGTPEARLGWYIVLGTVPAALAGKLLEHRIEALGNWVI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
AGSLVALGLVLLAAERLASHRRRVEDVGAGDALLIGVAQALALVPGSSRSGTTITGGMLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEECHHHH
GFTREAAARFSFLLSVPITLAAGAYKLWSTVPDLRGEAAWTVATVVGTVVSAVAGYLVID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WLLAWLRTRTTYVFVVWRLAAGAAIAALILSGVLPAGAEAPPPPPPALHAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA