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The map label for this gene is asd [H]

Identifier: 220905535

GI number: 220905535

Start: 2738098

End: 2739144

Strand: Direct

Name: asd [H]

Synonym: Ddes_2274

Alternate gene names: 220905535

Gene position: 2738098-2739144 (Clockwise)

Preceding gene: 220905534

Following gene: 220905536

Centisome position: 95.29

GC content: 57.69

Gene sequence:

>1047_bases
ATGAGCAAGAAGCTGACTGTTGCCGTTGTTGGCGCCACTGGCGCCGTAGGCCGTGAAATGCTCAAGACCCTTCACGAGCG
CGACTTTCCCGCCACCGAAATCCGTGCCTTTGCTTCCGCCCGTTCGGCGGGAACCAAGGTTCCTTTCGGCGAAAAGGAAC
TGACCGTTCAGGAACTTAAAGAAGACGTCTTTGAAGGCATTGACCTGGCCATTTTTTCCGCAGGCGGCGCCGCTTCGCTA
AAATTTGCCCCCCATGCGGCCCATGCCGGCTGCGTCGTGGTGGACAACTCCTCCACATGGCGCATGGATGACCGCTGCCC
CCTGGTGGTGCCCGAAGTCAACGCCCAGGCCCTGGAAGACCATAACGGCATCATCGCCAATCCCAACTGTTCTACCATCC
AGATGATGGTGGCGCTCAAGCCCCTGCACGATGCAGCCAAAATCAGGCGCGTGGTTGTTTCCACCTATCAGGCGGTTTCG
GGCACCGGGCAGAAGGGTATTGAAGAGCTGGAGCGCCAGGTGCGCGACCTCTTCAACGGGCGCGATCCAGAAAACAAGAC
CTACCCCTACCGCATTGCCTTCAACTGCCTGCCCCACATCGACGTTTTCCTTGAAAATGACTACACCAAGGAAGAAATGA
AGATGGTCCACGAAACCGTCAAGATTTTCAACGATCCGTCGGTCAAGGTCACGGCTACCTGCGTGCGCGTACCCGTTTTT
TACTGCCATGCCGAATCCGTCAACGTGGAAACGGAAAAAAAGCTTTCGGCCAGAGATGCCCGCGTTATGCTTGCGCAGGC
TCCGGGTGTGCGCGTGTTCGACAATCCCCGCGAGCTTATGTATCCCATGCCCGGCTACTGCGTGGGCGATGACCACACCT
ATGTGGGCCGTATTCGTGAGGACGAAACCATTGCAAACGGCCTCAACATGTGGATTGTGGCCGACAACGTGCGCAAGGGC
GCGGCCCTCAACACGGTGCAGATCGCCGAAGAGCTTGTGCAGCGCGGCCTTGTGCGCGTGACGGACAAAAACGTCTTTAT
GTCCTGA

Upstream 100 bases:

>100_bases
ATCAGGACTATACTGTCGCCTCACCGCGCGCATTTGCCGCGCTCTTTTTATCGGCGGCCCCGTAAGGCCGACGTGCATCG
CCCAAGGAGAGCGAAAAGCC

Downstream 100 bases:

>100_bases
TATTGAACGCATGCAGCAAACGTGCGGGGCGTTCTGCGCCCCGCGCGCCTTTTGAGGAGACGCCCTTGAAAGCAGTCGAT
GCCCATACCTATCTTGCGGC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSKKLTVAVVGATGAVGREMLKTLHERDFPATEIRAFASARSAGTKVPFGEKELTVQELKEDVFEGIDLAIFSAGGAASL
KFAPHAAHAGCVVVDNSSTWRMDDRCPLVVPEVNAQALEDHNGIIANPNCSTIQMMVALKPLHDAAKIRRVVVSTYQAVS
GTGQKGIEELERQVRDLFNGRDPENKTYPYRIAFNCLPHIDVFLENDYTKEEMKMVHETVKIFNDPSVKVTATCVRVPVF
YCHAESVNVETEKKLSARDARVMLAQAPGVRVFDNPRELMYPMPGYCVGDDHTYVGRIREDETIANGLNMWIVADNVRKG
AALNTVQIAEELVQRGLVRVTDKNVFMS

Sequences:

>Translated_348_residues
MSKKLTVAVVGATGAVGREMLKTLHERDFPATEIRAFASARSAGTKVPFGEKELTVQELKEDVFEGIDLAIFSAGGAASL
KFAPHAAHAGCVVVDNSSTWRMDDRCPLVVPEVNAQALEDHNGIIANPNCSTIQMMVALKPLHDAAKIRRVVVSTYQAVS
GTGQKGIEELERQVRDLFNGRDPENKTYPYRIAFNCLPHIDVFLENDYTKEEMKMVHETVKIFNDPSVKVTATCVRVPVF
YCHAESVNVETEKKLSARDARVMLAQAPGVRVFDNPRELMYPMPGYCVGDDHTYVGRIREDETIANGLNMWIVADNVRKG
AALNTVQIAEELVQRGLVRVTDKNVFMS
>Mature_347_residues
SKKLTVAVVGATGAVGREMLKTLHERDFPATEIRAFASARSAGTKVPFGEKELTVQELKEDVFEGIDLAIFSAGGAASLK
FAPHAAHAGCVVVDNSSTWRMDDRCPLVVPEVNAQALEDHNGIIANPNCSTIQMMVALKPLHDAAKIRRVVVSTYQAVSG
TGQKGIEELERQVRDLFNGRDPENKTYPYRIAFNCLPHIDVFLENDYTKEEMKMVHETVKIFNDPSVKVTATCVRVPVFY
CHAESVNVETEKKLSARDARVMLAQAPGVRVFDNPRELMYPMPGYCVGDDHTYVGRIREDETIANGLNMWIVADNVRKGA
ALNTVQIAEELVQRGLVRVTDKNVFMS

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=341, Percent_Identity=38.41642228739, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1789841, Length=353, Percent_Identity=27.1954674220963, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320362, Length=396, Percent_Identity=27.020202020202, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38496; Mature: 38364

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKLTVAVVGATGAVGREMLKTLHERDFPATEIRAFASARSAGTKVPFGEKELTVQELK
CCCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
EDVFEGIDLAIFSAGGAASLKFAPHAAHAGCVVVDNSSTWRMDDRCPLVVPEVNAQALED
HHHHCCCEEEEEECCCCCEEEECCCCCCCCEEEEECCCCEEECCCCCEEEECCCHHHHHC
HNGIIANPNCSTIQMMVALKPLHDAAKIRRVVVSTYQAVSGTGQKGIEELERQVRDLFNG
CCCEEECCCCCCEEEEEHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
RDPENKTYPYRIAFNCLPHIDVFLENDYTKEEMKMVHETVKIFNDPSVKVTATCVRVPVF
CCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEE
YCHAESVNVETEKKLSARDARVMLAQAPGVRVFDNPRELMYPMPGYCVGDDHTYVGRIRE
EEECCCCCCCHHHHHHHCCCEEEEEECCCCEEECCCHHHCCCCCCEEECCCCCEEEEECC
DETIANGLNMWIVADNVRKGAALNTVQIAEELVQRGLVRVTDKNVFMS
CHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCEECC
>Mature Secondary Structure 
SKKLTVAVVGATGAVGREMLKTLHERDFPATEIRAFASARSAGTKVPFGEKELTVQELK
CCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
EDVFEGIDLAIFSAGGAASLKFAPHAAHAGCVVVDNSSTWRMDDRCPLVVPEVNAQALED
HHHHCCCEEEEEECCCCCEEEECCCCCCCCEEEEECCCCEEECCCCCEEEECCCHHHHHC
HNGIIANPNCSTIQMMVALKPLHDAAKIRRVVVSTYQAVSGTGQKGIEELERQVRDLFNG
CCCEEECCCCCCEEEEEHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
RDPENKTYPYRIAFNCLPHIDVFLENDYTKEEMKMVHETVKIFNDPSVKVTATCVRVPVF
CCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEE
YCHAESVNVETEKKLSARDARVMLAQAPGVRVFDNPRELMYPMPGYCVGDDHTYVGRIRE
EEECCCCCCCHHHHHHHCCCEEEEEECCCCEEECCCHHHCCCCCCEEECCCCCEEEEECC
DETIANGLNMWIVADNVRKGAALNTVQIAEELVQRGLVRVTDKNVFMS
CHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]