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The map label for this gene is asnC [H]

Identifier: 220905534

GI number: 220905534

Start: 2736247

End: 2737611

Strand: Direct

Name: asnC [H]

Synonym: Ddes_2273

Alternate gene names: 220905534

Gene position: 2736247-2737611 (Clockwise)

Preceding gene: 220905531

Following gene: 220905535

Centisome position: 95.23

GC content: 59.05

Gene sequence:

>1365_bases
ATGCAGCGAACCCTGATTATCGACGCTCTCAACTCCACATCGGCCCAGCCCGCCATAGTCCTGTGTGGCTGGATACGCAC
ACGCCGCGACGCCAAGGATTTCAGCTTTGTGGAAATCAACGACGGTTCCTGCCTCGCCAACATGCAATGCATCGTGGACG
CGGGTACGCCTGCCCATCAGGGCCTCGGCGATGCGGCCACAGGCGCTGCCGTGCGCGTGACGGGCGAACTTGTATCCTCG
CCGGGCAAAGGGCAGCAGTGGGAGGTGCGCGCGCATGACGTGCAGGTTTACGGCCTGGCCGACCCCGAAAATTTTCCTTT
GCAGAAAAAACGCCATTCCGACGAATTTTTGCGCACCATTGCCCACCTGCGGCCGCGAACCAACAAGTACGGAGCCGTAT
TCCGCATCCGCTCCGAGGCTGGCTTTGCCGTTCACGATTTTTTCCGCAGCCGCCGCTTCGCCTGGGTGCATACCCCTGTA
CTTACCGGCGCGGACTGTGAGGGCGCGGGCGAGATGTTCCGCGTGACCACACTTGAGCCGGGCGCAAAAAACCTGGATCA
GGATTTTTTCAGCCGCCAGTGCAACCTGACGGTTTCAGGCCAGCTTGAGGCTGAAGCCCTGGCCACGGGCCTTGGGCGGG
TGTACAGTTTTGGCCCGACCTTCCGGGCAGAAAATTCCAACACGCCGCGCCACGCCGCCGAATTCTGGATGATCGAGCCG
GAAATGGCCTTTGCCGATCTGGAAGACCTTATGGAGCTGGGTGAAGGGCTTACCCGGCACGTAGTGGACCATGTGCTCAC
CCGTTGCGAAAGCGACGTGAATCTTTTTGACAGCTTTGTGGACAAGGGCCTGCGCCAGCGCCTGCAGGACATGCTGGCTG
CGCCCTTTGGTCGTGTGTCCTACACGGAGGCCGTGGAAATTCTGCAGAAAAGCGGCAAGGATTTTGCCTTTCCCGTTGCT
TTCGGTACAGACCTGCAAACCGAACATGAGCGTTACCTGGCGGAAGAACACTTTAAAAAGCCTGTTATCGTTTATGATTA
CCCCAAAGATATCAAGGCGTTTTACATGCGCCAGAATGAGGATGGCAAAACCGTGGCCGCTATGGACATGCTGGTTCCGC
GCATCGGCGAGCTTATCGGCGGATCGCAGCGCGAAGAGCGCCTGCCCACACTTGAGGCCCGCATACGCGAAATGGGGCAT
AACCCGGAAGATTACTGGTGGTATCTCGAACTGCGCCGCTTCGGCACTGTGCCTCACGCCGGTTTCGGCCTGGGCTTCGA
GCGCCTGCTCATGCTGCTCACGGGCATTACCAATATCCGCGATGTCATCCCCTTCCCCCGTACGCCGGGCAATCTGGAAT
TTTAG

Upstream 100 bases:

>100_bases
CGCAGTCAGAGGTGGCGCACGCCATGCGGCGGCTCCGCTCTTGAGCCTGCCTCACGGAAGCGCTACACTTGCACAAATTT
CATTCACCGAGGAGCCTGCC

Downstream 100 bases:

>100_bases
GCCATAATGGCCTGAACTGCAGCAGCTATCCATCTTCGTCCTCGGCAGCGTAAAGGTACAAAACTGTTCCGCCGGGCGGC
ATCGCCCGGCGGAACAGCCA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MQRTLIIDALNSTSAQPAIVLCGWIRTRRDAKDFSFVEINDGSCLANMQCIVDAGTPAHQGLGDAATGAAVRVTGELVSS
PGKGQQWEVRAHDVQVYGLADPENFPLQKKRHSDEFLRTIAHLRPRTNKYGAVFRIRSEAGFAVHDFFRSRRFAWVHTPV
LTGADCEGAGEMFRVTTLEPGAKNLDQDFFSRQCNLTVSGQLEAEALATGLGRVYSFGPTFRAENSNTPRHAAEFWMIEP
EMAFADLEDLMELGEGLTRHVVDHVLTRCESDVNLFDSFVDKGLRQRLQDMLAAPFGRVSYTEAVEILQKSGKDFAFPVA
FGTDLQTEHERYLAEEHFKKPVIVYDYPKDIKAFYMRQNEDGKTVAAMDMLVPRIGELIGGSQREERLPTLEARIREMGH
NPEDYWWYLELRRFGTVPHAGFGLGFERLLMLLTGITNIRDVIPFPRTPGNLEF

Sequences:

>Translated_454_residues
MQRTLIIDALNSTSAQPAIVLCGWIRTRRDAKDFSFVEINDGSCLANMQCIVDAGTPAHQGLGDAATGAAVRVTGELVSS
PGKGQQWEVRAHDVQVYGLADPENFPLQKKRHSDEFLRTIAHLRPRTNKYGAVFRIRSEAGFAVHDFFRSRRFAWVHTPV
LTGADCEGAGEMFRVTTLEPGAKNLDQDFFSRQCNLTVSGQLEAEALATGLGRVYSFGPTFRAENSNTPRHAAEFWMIEP
EMAFADLEDLMELGEGLTRHVVDHVLTRCESDVNLFDSFVDKGLRQRLQDMLAAPFGRVSYTEAVEILQKSGKDFAFPVA
FGTDLQTEHERYLAEEHFKKPVIVYDYPKDIKAFYMRQNEDGKTVAAMDMLVPRIGELIGGSQREERLPTLEARIREMGH
NPEDYWWYLELRRFGTVPHAGFGLGFERLLMLLTGITNIRDVIPFPRTPGNLEF
>Mature_454_residues
MQRTLIIDALNSTSAQPAIVLCGWIRTRRDAKDFSFVEINDGSCLANMQCIVDAGTPAHQGLGDAATGAAVRVTGELVSS
PGKGQQWEVRAHDVQVYGLADPENFPLQKKRHSDEFLRTIAHLRPRTNKYGAVFRIRSEAGFAVHDFFRSRRFAWVHTPV
LTGADCEGAGEMFRVTTLEPGAKNLDQDFFSRQCNLTVSGQLEAEALATGLGRVYSFGPTFRAENSNTPRHAAEFWMIEP
EMAFADLEDLMELGEGLTRHVVDHVLTRCESDVNLFDSFVDKGLRQRLQDMLAAPFGRVSYTEAVEILQKSGKDFAFPVA
FGTDLQTEHERYLAEEHFKKPVIVYDYPKDIKAFYMRQNEDGKTVAAMDMLVPRIGELIGGSQREERLPTLEARIREMGH
NPEDYWWYLELRRFGTVPHAGFGLGFERLLMLLTGITNIRDVIPFPRTPGNLEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=449, Percent_Identity=47.2160356347439, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI4758762, Length=457, Percent_Identity=29.9781181619256, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI45439306, Length=349, Percent_Identity=29.2263610315186, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1787161, Length=447, Percent_Identity=55.0335570469799, Blast_Score=507, Evalue=1e-145,
Organism=Escherichia coli, GI1789256, Length=383, Percent_Identity=25.8485639686684, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790571, Length=384, Percent_Identity=25.78125, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788173, Length=108, Percent_Identity=36.1111111111111, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17556372, Length=423, Percent_Identity=34.2789598108747, Blast_Score=197, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI71984122, Length=441, Percent_Identity=30.1587301587302, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17551876, Length=348, Percent_Identity=29.5977011494253, Blast_Score=114, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6319872, Length=471, Percent_Identity=35.8811040339703, Blast_Score=286, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6321807, Length=463, Percent_Identity=28.0777537796976, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323011, Length=351, Percent_Identity=31.0541310541311, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI19922416, Length=463, Percent_Identity=36.2850971922246, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI19921528, Length=438, Percent_Identity=29.2237442922374, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI17136276, Length=347, Percent_Identity=27.9538904899135, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 51141; Mature: 51141

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRTLIIDALNSTSAQPAIVLCGWIRTRRDAKDFSFVEINDGSCLANMQCIVDAGTPAHQ
CCCEEEEEECCCCCCCCEEEEEEHHHHCCCCCCCEEEEECCCCEEECEEEEEECCCCHHC
GLGDAATGAAVRVTGELVSSPGKGQQWEVRAHDVQVYGLADPENFPLQKKRHSDEFLRTI
CCCCCCCCCEEEEEHHHHCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHCCHHHHHHHH
AHLRPRTNKYGAVFRIRSEAGFAVHDFFRSRRFAWVHTPVLTGADCEGAGEMFRVTTLEP
HHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCEEEEECCEEECCCCCCCCCEEEEEEECC
GAKNLDQDFFSRQCNLTVSGQLEAEALATGLGRVYSFGPTFRAENSNTPRHAAEFWMIEP
CCCCCCHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHEEEECC
EMAFADLEDLMELGEGLTRHVVDHVLTRCESDVNLFDSFVDKGLRQRLQDMLAAPFGRVS
CHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
YTEAVEILQKSGKDFAFPVAFGTDLQTEHERYLAEEHFKKPVIVYDYPKDIKAFYMRQNE
HHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHEEECC
DGKTVAAMDMLVPRIGELIGGSQREERLPTLEARIREMGHNPEDYWWYLELRRFGTVPHA
CCCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCCCCCEEEEEEEEHHCCCCCC
GFGLGFERLLMLLTGITNIRDVIPFPRTPGNLEF
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQRTLIIDALNSTSAQPAIVLCGWIRTRRDAKDFSFVEINDGSCLANMQCIVDAGTPAHQ
CCCEEEEEECCCCCCCCEEEEEEHHHHCCCCCCCEEEEECCCCEEECEEEEEECCCCHHC
GLGDAATGAAVRVTGELVSSPGKGQQWEVRAHDVQVYGLADPENFPLQKKRHSDEFLRTI
CCCCCCCCCEEEEEHHHHCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHCCHHHHHHHH
AHLRPRTNKYGAVFRIRSEAGFAVHDFFRSRRFAWVHTPVLTGADCEGAGEMFRVTTLEP
HHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCEEEEECCEEECCCCCCCCCEEEEEEECC
GAKNLDQDFFSRQCNLTVSGQLEAEALATGLGRVYSFGPTFRAENSNTPRHAAEFWMIEP
CCCCCCHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHEEEECC
EMAFADLEDLMELGEGLTRHVVDHVLTRCESDVNLFDSFVDKGLRQRLQDMLAAPFGRVS
CHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
YTEAVEILQKSGKDFAFPVAFGTDLQTEHERYLAEEHFKKPVIVYDYPKDIKAFYMRQNE
HHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHEEECC
DGKTVAAMDMLVPRIGELIGGSQREERLPTLEARIREMGHNPEDYWWYLELRRFGTVPHA
CCCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCCCCCEEEEEEEEHHCCCCCC
GFGLGFERLLMLLTGITNIRDVIPFPRTPGNLEF
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA