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The map label for this gene is comEB [H]

Identifier: 220904883

GI number: 220904883

Start: 1943357

End: 1943833

Strand: Direct

Name: comEB [H]

Synonym: Ddes_1618

Alternate gene names: 220904883

Gene position: 1943357-1943833 (Clockwise)

Preceding gene: 220904882

Following gene: 220904884

Centisome position: 67.63

GC content: 58.7

Gene sequence:

>477_bases
ATGCAAAGATTGCCCTGGCCCGAGTACTTCATGAACATCACCTACCTTGTCAGTGGGCGCTCCACCTGCACGCGCCGCCG
GGTGGGGGCTGTGGCAGTGAAGGACAAACGCATTCTCGCCACCGGCTATAACGGTGCGCCCGCGGGAGTTCCCCACTGTC
TTGAGGTAGGCTGCCTGCGCGAACAGATGGGCATTCCATCGGGACAGAGGCATGAAATCTGCCGGGGGCTGCACGCAGAA
CAGAACGTTATCATCCAGGCGGCCGTGCACGGCATAAATATCAGCGGAGCCGAACTGTACTGCACCACCCATCCCTGCGT
GCAATGCAGCAAAATGCTTATCAACTGCGGTATAAGGCGCATCTATTACGCCGAGCACTATCCTGACGAGCTTGCCACTA
CCATGCTCAAGGAAGCCGGGATTCAACTGGAAAGGCTGGACTTTACCCCACCCGCCATAAGCCCCCGGCCGGAGTAG

Upstream 100 bases:

>100_bases
CTGGCTCCGGTGAAACAGCCTTTATGCCGAAAAGCCGAACCGTCGGCTTGGCTTTTACGCTTCCCCTATGTACACTAGCG
AAAAATTTAACGGATATCCC

Downstream 100 bases:

>100_bases
CCATGTCTGAACTGGATTACACCCCCTTTATGCGCGAAGCCATCGCGCTGGCACAACAGGGCCGCTGGAAGACCTGCCCC
AACCCTATGGTGGGGGCTGT

Product: CMP/dCMP deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MQRLPWPEYFMNITYLVSGRSTCTRRRVGAVAVKDKRILATGYNGAPAGVPHCLEVGCLREQMGIPSGQRHEICRGLHAE
QNVIIQAAVHGINISGAELYCTTHPCVQCSKMLINCGIRRIYYAEHYPDELATTMLKEAGIQLERLDFTPPAISPRPE

Sequences:

>Translated_158_residues
MQRLPWPEYFMNITYLVSGRSTCTRRRVGAVAVKDKRILATGYNGAPAGVPHCLEVGCLREQMGIPSGQRHEICRGLHAE
QNVIIQAAVHGINISGAELYCTTHPCVQCSKMLINCGIRRIYYAEHYPDELATTMLKEAGIQLERLDFTPPAISPRPE
>Mature_158_residues
MQRLPWPEYFMNITYLVSGRSTCTRRRVGAVAVKDKRILATGYNGAPAGVPHCLEVGCLREQMGIPSGQRHEICRGLHAE
QNVIIQAAVHGINISGAELYCTTHPCVQCSKMLINCGIRRIYYAEHYPDELATTMLKEAGIQLERLDFTPPAISPRPE

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321938, Length=150, Percent_Identity=38, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 17609; Mature: 17609

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLPWPEYFMNITYLVSGRSTCTRRRVGAVAVKDKRILATGYNGAPAGVPHCLEVGCLR
CCCCCCHHHHHEEEEEEECCCHHHHHHCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHH
EQMGIPSGQRHEICRGLHAEQNVIIQAAVHGINISGAELYCTTHPCVQCSKMLINCGIRR
HHHCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHCCHHE
IYYAEHYPDELATTMLKEAGIQLERLDFTPPAISPRPE
EEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MQRLPWPEYFMNITYLVSGRSTCTRRRVGAVAVKDKRILATGYNGAPAGVPHCLEVGCLR
CCCCCCHHHHHEEEEEEECCCHHHHHHCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHH
EQMGIPSGQRHEICRGLHAEQNVIIQAAVHGINISGAELYCTTHPCVQCSKMLINCGIRR
HHHCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHCCHHE
IYYAEHYPDELATTMLKEAGIQLERLDFTPPAISPRPE
EEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]