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The map label for this gene is ribD [H]

Identifier: 220904884

GI number: 220904884

Start: 1943836

End: 1944993

Strand: Direct

Name: ribD [H]

Synonym: Ddes_1619

Alternate gene names: 220904884

Gene position: 1943836-1944993 (Clockwise)

Preceding gene: 220904883

Following gene: 220904885

Centisome position: 67.65

GC content: 63.9

Gene sequence:

>1158_bases
ATGTCTGAACTGGATTACACCCCCTTTATGCGCGAAGCCATCGCGCTGGCACAACAGGGCCGCTGGAAGACCTGCCCCAA
CCCTATGGTGGGGGCTGTTCTTGTGCGCGATGGACACATTGTCGCCAGGGGCTGGCATCGCGCCTTCGGGCTGGACCATG
CCGAGGTGGACTGCCTTAATGACGCTGCCGCGCAAGGAGTCGACCCTTCTGAGTGTACGCTGGTTGTCACGCTTGAACCG
TGCTGCCATCAGGGCAAAACTCCCCCCTGCACCGATGCCGTGCTGCGGGCAGGCATAAAAAAAATCGTGGTGGGGCTGTC
CGACCCCAATCCCGAAGCCTGCGGCGGCGCATGCCGGCTGCGCGAATCCGGCCTGGATGTCATTGAGGGCGTCTGCGCAG
ATGCCTGCCGTGACCTTGTGGCAGATTTTCTTGTCTGGCAGCAGGCACAGCGCCCCTACGTGATTCTTAAAATGGCCGCC
ACACTTGATGGGCGTATAGCCACGCGCAAGGGCGAGTCGCAGTGGATCAGTTCGGAAGAATCCCGGCAGGAAGTACAGCG
CCTCAGGGCCGGCATAGGCCGCTGCGGCGGCGCTGTACTTGTGGGCGGGGGCACGTTCAGGGCTGACGATCCGCGGCTTA
CCGTGCGGCCCATCAATGATGGCGAGCCTCTCGGCCCGCAGCCCCTGGCCTGCGTGCTCACCTCACGCCTGCCCCAGCCG
GATGCCGATTTTTACCTGCTCAAAGAGCGGCCCCAGCAGACCGTATTTCTGGCCTCGCCTGCTGCGGCGGCCTCCACCAC
AGCCAAGGCCCTGCGCGACATGGGAGTGCGCGTTCTTTCACTGGGGCCGAGCCTGCGCGGCGGGCCGGACCTGACCCATA
TGCTGCGCACAATGCGTGAAGAGCTGGATTGCCCCTATCTGCTGTGCGAAGGCGGCGGGCATCTGGCCCTCAGCCTTCTT
GAGGCTGGCGTTGTGGACGAATTCCGCCTGCATATGGCCCCGATGATTCTGGGAGACGCGGACGCGCAACCGCTTTTTTC
CGGCCGTGCCCCCCTCAGCCTGGACGAAGCCCTGCGCATGCGCGTGACAGGCAGCCACATCAGCGGGGGCGACATCCATA
TTGAGCTGCGCCCGCTGCAAGCCGTGGAAGAAAAGTAG

Upstream 100 bases:

>100_bases
ATCCTGACGAGCTTGCCACTACCATGCTCAAGGAAGCCGGGATTCAACTGGAAAGGCTGGACTTTACCCCACCCGCCATA
AGCCCCCGGCCGGAGTAGCC

Downstream 100 bases:

>100_bases
GAAATCATGTTTACCGGTATCATACAGGGACAGGGCGAGGTGCGCTCCATGCGTAAAAGCGGCACGGAATGCCGTATATG
TCTGCGCCCCCTGTTTACCT

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSELDYTPFMREAIALAQQGRWKTCPNPMVGAVLVRDGHIVARGWHRAFGLDHAEVDCLNDAAAQGVDPSECTLVVTLEP
CCHQGKTPPCTDAVLRAGIKKIVVGLSDPNPEACGGACRLRESGLDVIEGVCADACRDLVADFLVWQQAQRPYVILKMAA
TLDGRIATRKGESQWISSEESRQEVQRLRAGIGRCGGAVLVGGGTFRADDPRLTVRPINDGEPLGPQPLACVLTSRLPQP
DADFYLLKERPQQTVFLASPAAAASTTAKALRDMGVRVLSLGPSLRGGPDLTHMLRTMREELDCPYLLCEGGGHLALSLL
EAGVVDEFRLHMAPMILGDADAQPLFSGRAPLSLDEALRMRVTGSHISGGDIHIELRPLQAVEEK

Sequences:

>Translated_385_residues
MSELDYTPFMREAIALAQQGRWKTCPNPMVGAVLVRDGHIVARGWHRAFGLDHAEVDCLNDAAAQGVDPSECTLVVTLEP
CCHQGKTPPCTDAVLRAGIKKIVVGLSDPNPEACGGACRLRESGLDVIEGVCADACRDLVADFLVWQQAQRPYVILKMAA
TLDGRIATRKGESQWISSEESRQEVQRLRAGIGRCGGAVLVGGGTFRADDPRLTVRPINDGEPLGPQPLACVLTSRLPQP
DADFYLLKERPQQTVFLASPAAAASTTAKALRDMGVRVLSLGPSLRGGPDLTHMLRTMREELDCPYLLCEGGGHLALSLL
EAGVVDEFRLHMAPMILGDADAQPLFSGRAPLSLDEALRMRVTGSHISGGDIHIELRPLQAVEEK
>Mature_384_residues
SELDYTPFMREAIALAQQGRWKTCPNPMVGAVLVRDGHIVARGWHRAFGLDHAEVDCLNDAAAQGVDPSECTLVVTLEPC
CHQGKTPPCTDAVLRAGIKKIVVGLSDPNPEACGGACRLRESGLDVIEGVCADACRDLVADFLVWQQAQRPYVILKMAAT
LDGRIATRKGESQWISSEESRQEVQRLRAGIGRCGGAVLVGGGTFRADDPRLTVRPINDGEPLGPQPLACVLTSRLPQPD
ADFYLLKERPQQTVFLASPAAAASTTAKALRDMGVRVLSLGPSLRGGPDLTHMLRTMREELDCPYLLCEGGGHLALSLLE
AGVVDEFRLHMAPMILGDADAQPLFSGRAPLSLDEALRMRVTGSHISGGDIHIELRPLQAVEEK

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=349, Percent_Identity=38.3954154727794, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI145693172, Length=157, Percent_Identity=32.484076433121, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 41449; Mature: 41318

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELDYTPFMREAIALAQQGRWKTCPNPMVGAVLVRDGHIVARGWHRAFGLDHAEVDCLN
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEEECHHHHHCCCCHHHHHHH
DAAAQGVDPSECTLVVTLEPCCHQGKTPPCTDAVLRAGIKKIVVGLSDPNPEACGGACRL
HHHHCCCCCCCCEEEEEECHHHCCCCCCCHHHHHHHHCHHHEEEECCCCCCHHCCCHHHH
RESGLDVIEGVCADACRDLVADFLVWQQAQRPYVILKMAATLDGRIATRKGESQWISSEE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCHHHCCCHH
SRQEVQRLRAGIGRCGGAVLVGGGTFRADDPRLTVRPINDGEPLGPQPLACVLTSRLPQP
HHHHHHHHHHHHCCCCCEEEECCCEEECCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCC
DADFYLLKERPQQTVFLASPAAAASTTAKALRDMGVRVLSLGPSLRGGPDLTHMLRTMRE
CCCEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHH
ELDCPYLLCEGGGHLALSLLEAGVVDEFRLHMAPMILGDADAQPLFSGRAPLSLDEALRM
HCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHEE
RVTGSHISGGDIHIELRPLQAVEEK
EEECCCCCCCEEEEEEECCHHCCCC
>Mature Secondary Structure 
SELDYTPFMREAIALAQQGRWKTCPNPMVGAVLVRDGHIVARGWHRAFGLDHAEVDCLN
CCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEEECHHHHHCCCCHHHHHHH
DAAAQGVDPSECTLVVTLEPCCHQGKTPPCTDAVLRAGIKKIVVGLSDPNPEACGGACRL
HHHHCCCCCCCCEEEEEECHHHCCCCCCCHHHHHHHHCHHHEEEECCCCCCHHCCCHHHH
RESGLDVIEGVCADACRDLVADFLVWQQAQRPYVILKMAATLDGRIATRKGESQWISSEE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCHHHCCCHH
SRQEVQRLRAGIGRCGGAVLVGGGTFRADDPRLTVRPINDGEPLGPQPLACVLTSRLPQP
HHHHHHHHHHHHCCCCCEEEECCCEEECCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCC
DADFYLLKERPQQTVFLASPAAAASTTAKALRDMGVRVLSLGPSLRGGPDLTHMLRTMRE
CCCEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHH
ELDCPYLLCEGGGHLALSLLEAGVVDEFRLHMAPMILGDADAQPLFSGRAPLSLDEALRM
HCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHEE
RVTGSHISGGDIHIELRPLQAVEEK
EEECCCCCCCEEEEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]