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The map label for this gene is glyQ

Identifier: 220904188

GI number: 220904188

Start: 1065539

End: 1066417

Strand: Direct

Name: glyQ

Synonym: Ddes_0915

Alternate gene names: 220904188

Gene position: 1065539-1066417 (Clockwise)

Preceding gene: 220904187

Following gene: 220904189

Centisome position: 37.08

GC content: 58.02

Gene sequence:

>879_bases
ATGTATTTTCAGGACGTGATTCTCACCCTACAGAATTACTGGGCCAGGCAGGGCTGCGTTATCGAGCAGCCGTCAGGCGT
GGAATGCGGGGCCGGAACTTTCAATCCTCATACCTTTTTGCGGGTTATCGGTCCCGAACCCTGGAATGTGGCCTACGTGG
AGCCTTCGCGGCGTCCCACAGACGGCCGTTACGGCGAAAATCCCAATCGCTTGCAGCGCTATTTCCAGTTTCAGGTCATC
ATGAAGCCCTCGCCGGACAACGTGCAGGACCTGTATCTGCAAAGCCTCAACGCTCTGGGCATCAATCCTGCCCAGCATGA
CATCCGCTTTGTGGAAGACGACTGGGAATCGCCGACCCTGGGGGCCTGGGGCCTCGGCTGGGAAGTGTGGCTCAACGGTA
TGGAGGTGAGCCAGTTCACCTATTTCCAGCAGGTGGGTGGTATCGACCTTGCGCCTGTGAGCGTGGAGCTGACCTACGGT
CTTGAGCGCCTGGCCATGTATCTTCAGGGTGTGGAATCCGTATACGATCTGGCCTGGAACAAAGACGTGACCTACGGCAA
TATCTACCACCAGAACGAGGTGGAGCAGTCGCGCCATAATTTCGAGGCCAGCGATGCCCAGATGCTGCTGCGCCATTTCA
ATGATTTTGAAGGCCAGTGCAAGGCTATGCTCGAACTGGGCTTGCCCTGGCCCGCCTATGACTATTGCCTGAAGTGTTCG
CATACCTTCAACCTGCTGGACGCGCGCGGGGCCATATCCATTACGGAACGCACCGGCTATATCGGCCGGGTGCGGGCTCT
GGCGGCGGGCGTTGCCCGTCTGTACGCGGCTCAGCGCGAAGAACTGGGCTATCCCATGCTCAAAAAGGATGCGAGGTAA

Upstream 100 bases:

>100_bases
CCGGGCGCAGATATATCGCCCGCAGCGACGGTGTGCCGTTCATGCCGTTGCTCCGCCAGGAAGCAAAAATCCTTTTGATC
AGCCTTCCAAAGGACAGCAC

Downstream 100 bases:

>100_bases
AGCCGTGGCCACCTTTGTGCTCGAAATCGGCAGTGAAGAACTGCCTTCCCGTTTTTTGGCTCCCGAAGAAGCGGAACTTT
TCACCCGTTTTACCACGGCT

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MYFQDVILTLQNYWARQGCVIEQPSGVECGAGTFNPHTFLRVIGPEPWNVAYVEPSRRPTDGRYGENPNRLQRYFQFQVI
MKPSPDNVQDLYLQSLNALGINPAQHDIRFVEDDWESPTLGAWGLGWEVWLNGMEVSQFTYFQQVGGIDLAPVSVELTYG
LERLAMYLQGVESVYDLAWNKDVTYGNIYHQNEVEQSRHNFEASDAQMLLRHFNDFEGQCKAMLELGLPWPAYDYCLKCS
HTFNLLDARGAISITERTGYIGRVRALAAGVARLYAAQREELGYPMLKKDAR

Sequences:

>Translated_292_residues
MYFQDVILTLQNYWARQGCVIEQPSGVECGAGTFNPHTFLRVIGPEPWNVAYVEPSRRPTDGRYGENPNRLQRYFQFQVI
MKPSPDNVQDLYLQSLNALGINPAQHDIRFVEDDWESPTLGAWGLGWEVWLNGMEVSQFTYFQQVGGIDLAPVSVELTYG
LERLAMYLQGVESVYDLAWNKDVTYGNIYHQNEVEQSRHNFEASDAQMLLRHFNDFEGQCKAMLELGLPWPAYDYCLKCS
HTFNLLDARGAISITERTGYIGRVRALAAGVARLYAAQREELGYPMLKKDAR
>Mature_292_residues
MYFQDVILTLQNYWARQGCVIEQPSGVECGAGTFNPHTFLRVIGPEPWNVAYVEPSRRPTDGRYGENPNRLQRYFQFQVI
MKPSPDNVQDLYLQSLNALGINPAQHDIRFVEDDWESPTLGAWGLGWEVWLNGMEVSQFTYFQQVGGIDLAPVSVELTYG
LERLAMYLQGVESVYDLAWNKDVTYGNIYHQNEVEQSRHNFEASDAQMLLRHFNDFEGQCKAMLELGLPWPAYDYCLKCS
HTFNLLDARGAISITERTGYIGRVRALAAGVARLYAAQREELGYPMLKKDAR

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=294, Percent_Identity=64.6258503401361, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_DESDA (B8IZ95)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002479500.1
- GeneID:   7284591
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_0915
- HOGENOM:   HBG285316
- ProtClustDB:   PRK09348
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 33396; Mature: 33396

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFQDVILTLQNYWARQGCVIEQPSGVECGAGTFNPHTFLRVIGPEPWNVAYVEPSRRPT
CCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCC
DGRYGENPNRLQRYFQFQVIMKPSPDNVQDLYLQSLNALGINPAQHDIRFVEDDWESPTL
CCCCCCCHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHCCEEEECCCCCCCC
GAWGLGWEVWLNGMEVSQFTYFQQVGGIDLAPVSVELTYGLERLAMYLQGVESVYDLAWN
CCCCCCHHHHCCCCCHHHHHHHHHHCCCEECCEEEEEHHCHHHHHHHHHHHHHHHHHHCC
KDVTYGNIYHQNEVEQSRHNFEASDAQMLLRHFNDFEGQCKAMLELGLPWPAYDYCLKCS
CCCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHEECC
HTFNLLDARGAISITERTGYIGRVRALAAGVARLYAAQREELGYPMLKKDAR
CCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MYFQDVILTLQNYWARQGCVIEQPSGVECGAGTFNPHTFLRVIGPEPWNVAYVEPSRRPT
CCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCC
DGRYGENPNRLQRYFQFQVIMKPSPDNVQDLYLQSLNALGINPAQHDIRFVEDDWESPTL
CCCCCCCHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHCCEEEECCCCCCCC
GAWGLGWEVWLNGMEVSQFTYFQQVGGIDLAPVSVELTYGLERLAMYLQGVESVYDLAWN
CCCCCCHHHHCCCCCHHHHHHHHHHCCCEECCEEEEEHHCHHHHHHHHHHHHHHHHHHCC
KDVTYGNIYHQNEVEQSRHNFEASDAQMLLRHFNDFEGQCKAMLELGLPWPAYDYCLKCS
CCCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHEECC
HTFNLLDARGAISITERTGYIGRVRALAAGVARLYAAQREELGYPMLKKDAR
CCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA