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The map label for this gene is glpT [H]

Identifier: 21909847

GI number: 21909847

Start: 353006

End: 354343

Strand: Direct

Name: glpT [H]

Synonym: SpyM3_0311

Alternate gene names: 21909847

Gene position: 353006-354343 (Clockwise)

Preceding gene: 21909846

Following gene: 21909848

Centisome position: 18.57

GC content: 42.3

Gene sequence:

>1338_bases
ATGGAAGAGGATTATAACAAAAGAGAACCTGAGAAGTTTACGCAATTTCTGCGCCGTCAAAAGGTTGTCTTTTTTGTCGC
ATTTTTTGGTTATGTGTGCGCTTACTTGGTACGCAACAATTTCAAACTAATGTCAAACACTATTATGGTACAAAATGGTT
GGGACAAGGCTCAAATTGCGACCTTGCTATCGTGTTTGACCGTTTCTTATGGTTTAGCAAAATTCTATATGGGAGCCTTA
GGGGATCGTGTTAGCTTGAGAAAGCTCTTTTCAATCAGCTTGGGTGCAAGCGCTTTGATTTGTATTTTAATTGGTTTTTT
CAATAGTTCAATGGTGGTGTTAGGGATACTGCTAGTCTTGTGTGGTGTCGTACAAGGTGCCTTGGCACCTGCCTCACAAG
CCATGATTGCCAATTATTTTCCAAATAAAACACGCGGCGGAGCCATCGCTGGATGGAACATTTCTCAAAACATGGGATCA
GCCCTCTTGCCATTAACCATCGCCTTGCTCACCAGTATGGGCTTGGTGGTACCAGCTAATGGCAATATTTTACTTGCATT
TTTAATTCCTGGTGTTTTAGTGTTCTTGTTTGCTTTGTGTTGCTGGAAGCTTGGCGGTGATAACCCTGAGTCTGAGGGAC
TTGACTCTCTTCGAACGATGTATGGTGATGCGGGCGAATCAGCTGTTGCCAGTGAAGAAGAAAAGCATAACCTGTCTTAT
TGGCAACTCATCTGGAAATACGTTTTTTGTAACCCGTCGCTCTTACTTGTTGCTGCTGTCAATGTGGCCCTTTATTTTGT
TCGTTTTGGGATTGAAGACTGGATGCCGATCTACTTGTCACAAGTAGCCAATATGTCAGAGGCCCATATTCATTTTGCGA
TTTCAATGTTAGAGTGGGTAGCTATTCCAGGCTCGCTGGTATTTGCGTGGTTAGCGGTTCGTTATCCTAATAAAATGGCC
AAGATTGGGGCTATTGGGCTTTTTGTGTTAGCGGCTATTGTGTTTGTCTATGAACGCTTGACTGCCACAGGTGCTCCAAA
CTATTTCTTGTTGCTTGTTATTGCAGGTATTTTAGGGTCATTGATTTATGGCCCACAGTTGATCGTGAATATTTTAACAA
TCAACTTTGTTCCTTTAAATGTTGCAGGAACAGCGATTGGTTTTGTAGGAGTAACAGCTTATCTCATCGGCAATATGGGA
GCAAACTGGCTGATGCCGATTTTGGCAGATGGTTTTGGCTGGTTTTGGTCATATATTGTCGTTGCAGCCTTATCTGCTTT
TTCAGCGGTTGGTTATTTGATTTTAGCCAAACGTGAGGAAGAAATCATCAAAGATTAG

Upstream 100 bases:

>100_bases
AGCAGTAAAATCGAATTTGTAAGCGTTGACACTGTTGCATAACTCTGTTACACTAAGAGAATGTCATGACAAAAATTACA
GTGTAGGAGTTTAATTGTTT

Downstream 100 bases:

>100_bases
CTAGGCAAATGCCTAAGAAAGACAGACTTATTGTTGAAGTCCTGTCTTTTTTAGTCATCACAAGCCGTAAATGACACTAT
AAAAGACAAGAAAATGCTAG

Product: putative glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGAL
GDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNLSY
WQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMA
KIGAIGLFVLAAIVFVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGNMG
ANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD

Sequences:

>Translated_445_residues
MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGAL
GDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNLSY
WQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMA
KIGAIGLFVLAAIVFVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGNMG
ANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD
>Mature_445_residues
MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGAL
GDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNLSY
WQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMA
KIGAIGLFVLAAIVFVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGNMG
ANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD

Specific function: The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=427, Percent_Identity=23.4192037470726, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4503847, Length=427, Percent_Identity=23.4192037470726, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI256219483, Length=427, Percent_Identity=23.4192037470726, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI256219543, Length=449, Percent_Identity=21.1581291759465, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1788573, Length=452, Percent_Identity=28.3185840707965, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI2367259, Length=393, Percent_Identity=27.4809160305344, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI87082310, Length=426, Percent_Identity=26.9953051643192, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI87082320, Length=302, Percent_Identity=21.8543046357616, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48663; Mature: 48663

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTIMVQNGWDKAQIA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEEECCCCHHHHH
TLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILLVL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHH
CGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGSALLPLTIALLTSMGLVVPAN
HHHHHHHCCCHHHHHHHHCCCCCCCCCEEECCCCHHHCCHHHHHHHHHHHHHCCEEEECC
GNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNLSY
CCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHCCCHHHCCHHH
WQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISMLEWV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIVFVYERLTATGAPNYFLLLVIAGILGS
HCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGNMGANWLMPILADGFGWFWSYIV
HHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VAALSAFSAVGYLILAKREEEIIKD
HHHHHHHHHHHHHHEECCHHHHHCC
>Mature Secondary Structure
MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLMSNTIMVQNGWDKAQIA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEEECCCCHHHHH
TLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICILIGFFNSSMVVLGILLVL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHH
CGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGSALLPLTIALLTSMGLVVPAN
HHHHHHHCCCHHHHHHHHCCCCCCCCCEEECCCCHHHCCHHHHHHHHHHHHHCCEEEECC
GNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLRTMYGDAGESAVASEEEKHNLSY
CCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHCCCHHHCCHHH
WQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMPIYLSQVANMSEAHIHFAISMLEWV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIVFVYERLTATGAPNYFLLLVIAGILGS
HCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LIYGPQLIVNILTINFVPLNVAGTAIGFVGVTAYLIGNMGANWLMPILADGFGWFWSYIV
HHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VAALSAFSAVGYLILAKREEEIIKD
HHHHHHHHHHHHHHEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 3042749 [H]