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The map label for this gene is rpl3p [H]

Identifier: 218884488

GI number: 218884488

Start: 1096327

End: 1097517

Strand: Reverse

Name: rpl3p [H]

Synonym: DKAM_1177

Alternate gene names: 218884488

Gene position: 1097517-1096327 (Counterclockwise)

Preceding gene: 218884489

Following gene: 218884487

Centisome position: 80.39

GC content: 47.44

Gene sequence:

>1191_bases
ATGGGTCATAGGAAGCTGCATGCGCCAAGACATGGCAGTCTAGGTGTAAGGCCAAGGAAGAGGGCTGAAGAGCTGACTCC
CAGAGTTAAGAGATGGCCTGAGAAATCATGGTTTGATATACTAGTTGAGAGGCTTGGAAACGAGGCTGCATCACAGGGTG
TAGTAGCTAGACCAGTGCTCCTGGGGTTCCCAGTATACAAGGCCGGGATGACTCATGCTATAATAGTTGAGGATAGACCC
AACACTCCGGTGACAGGTAAGGAGGTATTTACGCCTGTAACTATACTTGATGCACCACCGATAGTGGTGCTCGGTGTGAG
AACCTACATTATTGATGAGGAGGGATACTTGAAGACCAAGGGTGAGGCTTGGAGGAGCCCCTACGACGCTATTGCAAAAG
CTTTCGAGGAGCTCTATGCTGGTATCCCATTGATAGGAATTAGTGTAAAAGATGTTGTGAGGAAATATCTACATGGATTA
AGAAAGGTGAATCATGGACTAGTTAAGCCTGAGCCATCAAGTGAATATGGCTTCAAGTTTGTTGCCGAGAGTAGTGAAAG
CGAGTTAAGGGATGCTCTTAGCGGTGAGATAGCCGATGTGAGGGTAATAGCTTCAACGATACCGGTGTTATCTGGTATAG
GTAAGAAGAAGCCTGAAATAATTGAGTTGAAGATCGGTGGAGGCAGTATAGATGAGAGATTGAAGTATGCCGAAGGCATT
CTAGGCGGCTACGTTAGAGCATCGGATGTCTTCATGGAGGGACAGTTCGTGGATGTCATCGGTGTAACAAAGGGTAAGGG
TTTCCAGGGAGTTGTAAAGAGGTTTGGTGTTAAGGAGCTACCCAGATGGCATAAGCACAGGAAGGGTAGTAGGAAAATTG
GTGCCAGGAGCCCGGGCTTCGGTACTATGAGTGAGCCACCACAGGCCGGTCAAATGGGTTTCCATAGGAGGACCGAGTAT
AACAAGAGAATACTTAAGATGGGGTTGAATGGGTTGGAGATAACTATTGAAGGGGGCTTCCTACACTACGGGCTTGTTTA
CGGCCCATATATAATGCTTAAGGGCACAGTATTCGGGCCTGCAAAGAGAATGCTTATACTGCGCCACCCGATTAGACCTA
ACTTAAGATGGCTACCTCTCTCAGGCCCTAAGATAGCTTATTTAAGCCTTGAGAGCAAGCAGGGCATTTAG

Upstream 100 bases:

>100_bases
ACTGGTTGAAAAAAGAGTAGTGTATATAAGTGCTCATACATTATCTAACACTATGCTTTTAAAACCTGTTTACCTATAGA
AGCCTTGAAGGTGTTTAGGG

Downstream 100 bases:

>100_bases
GTGGTGGTTATGACTCTCGAGACAATTACTCCATTAGCCTTTAAGGAGAAAATAAAGGTCAACGTATACGGTGTCAACGG
CAACGTGGTCGGCGAGATTG

Product: 50S ribosomal protein L3P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MGHRKLHAPRHGSLGVRPRKRAEELTPRVKRWPEKSWFDILVERLGNEAASQGVVARPVLLGFPVYKAGMTHAIIVEDRP
NTPVTGKEVFTPVTILDAPPIVVLGVRTYIIDEEGYLKTKGEAWRSPYDAIAKAFEELYAGIPLIGISVKDVVRKYLHGL
RKVNHGLVKPEPSSEYGFKFVAESSESELRDALSGEIADVRVIASTIPVLSGIGKKKPEIIELKIGGGSIDERLKYAEGI
LGGYVRASDVFMEGQFVDVIGVTKGKGFQGVVKRFGVKELPRWHKHRKGSRKIGARSPGFGTMSEPPQAGQMGFHRRTEY
NKRILKMGLNGLEITIEGGFLHYGLVYGPYIMLKGTVFGPAKRMLILRHPIRPNLRWLPLSGPKIAYLSLESKQGI

Sequences:

>Translated_396_residues
MGHRKLHAPRHGSLGVRPRKRAEELTPRVKRWPEKSWFDILVERLGNEAASQGVVARPVLLGFPVYKAGMTHAIIVEDRP
NTPVTGKEVFTPVTILDAPPIVVLGVRTYIIDEEGYLKTKGEAWRSPYDAIAKAFEELYAGIPLIGISVKDVVRKYLHGL
RKVNHGLVKPEPSSEYGFKFVAESSESELRDALSGEIADVRVIASTIPVLSGIGKKKPEIIELKIGGGSIDERLKYAEGI
LGGYVRASDVFMEGQFVDVIGVTKGKGFQGVVKRFGVKELPRWHKHRKGSRKIGARSPGFGTMSEPPQAGQMGFHRRTEY
NKRILKMGLNGLEITIEGGFLHYGLVYGPYIMLKGTVFGPAKRMLILRHPIRPNLRWLPLSGPKIAYLSLESKQGI
>Mature_395_residues
GHRKLHAPRHGSLGVRPRKRAEELTPRVKRWPEKSWFDILVERLGNEAASQGVVARPVLLGFPVYKAGMTHAIIVEDRPN
TPVTGKEVFTPVTILDAPPIVVLGVRTYIIDEEGYLKTKGEAWRSPYDAIAKAFEELYAGIPLIGISVKDVVRKYLHGLR
KVNHGLVKPEPSSEYGFKFVAESSESELRDALSGEIADVRVIASTIPVLSGIGKKKPEIIELKIGGGSIDERLKYAEGIL
GGYVRASDVFMEGQFVDVIGVTKGKGFQGVVKRFGVKELPRWHKHRKGSRKIGARSPGFGTMSEPPQAGQMGFHRRTEYN
KRILKMGLNGLEITIEGGFLHYGLVYGPYIMLKGTVFGPAKRMLILRHPIRPNLRWLPLSGPKIAYLSLESKQGI

Specific function: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit [H]

COG id: COG0087

COG function: function code J; Ribosomal protein L3

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L3P family [H]

Homologues:

Organism=Homo sapiens, GI4506649, Length=422, Percent_Identity=32.7014218009479, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4826988, Length=421, Percent_Identity=29.9287410926366, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI76496472, Length=204, Percent_Identity=37.2549019607843, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71984538, Length=416, Percent_Identity=30.5288461538462, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71984550, Length=219, Percent_Identity=35.1598173515982, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71984544, Length=172, Percent_Identity=37.2093023255814, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324637, Length=419, Percent_Identity=31.7422434367542, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI17737907, Length=419, Percent_Identity=30.7875894988067, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24645877, Length=365, Percent_Identity=30.958904109589, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24645879, Length=365, Percent_Identity=30.958904109589, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24645875, Length=111, Percent_Identity=37.8378378378378, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000597
- InterPro:   IPR019928
- InterPro:   IPR019926
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00297 Ribosomal_L3 [H]

EC number: NA

Molecular weight: Translated: 43913; Mature: 43782

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS00474 RIBOSOMAL_L3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHRKLHAPRHGSLGVRPRKRAEELTPRVKRWPEKSWFDILVERLGNEAASQGVVARPVL
CCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHCCCCHHHHHHHHHHCCHHHHCCCEECHHH
LGFPVYKAGMTHAIIVEDRPNTPVTGKEVFTPVTILDAPPIVVLGVRTYIIDEEGYLKTK
HCCCHHHCCCCEEEEEECCCCCCCCCHHHCCCEEEECCCCEEEEEEEEEEECCCCCEECC
GEAWRSPYDAIAKAFEELYAGIPLIGISVKDVVRKYLHGLRKVNHGLVKPEPSSEYGFKF
CHHHCCHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VAESSESELRDALSGEIADVRVIASTIPVLSGIGKKKPEIIELKIGGGSIDERLKYAEGI
EECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHH
LGGYVRASDVFMEGQFVDVIGVTKGKGFQGVVKRFGVKELPRWHKHRKGSRKIGARSPGF
HHCCEEHHHEEECCCEEEEEEECCCCCHHHHHHHCCHHHCHHHHHHCCCCCCCCCCCCCC
GTMSEPPQAGQMGFHRRTEYNKRILKMGLNGLEITIEGGFLHYGLVYGPYIMLKGTVFGP
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEHHHHCCEEEEEECEECC
AKRMLILRHPIRPNLRWLPLSGPKIAYLSLESKQGI
HHHEEEEECCCCCCCEEEECCCCEEEEEEECCCCCC
>Mature Secondary Structure 
GHRKLHAPRHGSLGVRPRKRAEELTPRVKRWPEKSWFDILVERLGNEAASQGVVARPVL
CCCCCCCCCCCCCCCCCHHHHHHHCHHHHHCCCCHHHHHHHHHHCCHHHHCCCEECHHH
LGFPVYKAGMTHAIIVEDRPNTPVTGKEVFTPVTILDAPPIVVLGVRTYIIDEEGYLKTK
HCCCHHHCCCCEEEEEECCCCCCCCCHHHCCCEEEECCCCEEEEEEEEEEECCCCCEECC
GEAWRSPYDAIAKAFEELYAGIPLIGISVKDVVRKYLHGLRKVNHGLVKPEPSSEYGFKF
CHHHCCHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VAESSESELRDALSGEIADVRVIASTIPVLSGIGKKKPEIIELKIGGGSIDERLKYAEGI
EECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHH
LGGYVRASDVFMEGQFVDVIGVTKGKGFQGVVKRFGVKELPRWHKHRKGSRKIGARSPGF
HHCCEEHHHEEECCCEEEEEEECCCCCHHHHHHHCCHHHCHHHHHHCCCCCCCCCCCCCC
GTMSEPPQAGQMGFHRRTEYNKRILKMGLNGLEITIEGGFLHYGLVYGPYIMLKGTVFGP
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEHHHHCCEEEEEECEECC
AKRMLILRHPIRPNLRWLPLSGPKIAYLSLESKQGI
HHHEEEEECCCCCCCEEEECCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA