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The map label for this gene is sucC

Identifier: 218884352

GI number: 218884352

Start: 987619

End: 988758

Strand: Reverse

Name: sucC

Synonym: DKAM_1041

Alternate gene names: 218884352

Gene position: 988758-987619 (Counterclockwise)

Preceding gene: 218884361

Following gene: 218884351

Centisome position: 72.42

GC content: 47.46

Gene sequence:

>1140_bases
ATGAAACTGTATGAGTATGAAGGTAAGGAGATAGCTAGGAAGTATGGTATTGAGACCCCTAGAGGCATCCTTGCAACAAG
TGTTGAGGATGTGGATAAGGCATATAGAGAGTTGAACACGGGGACAGTAGTATTAAAATCCCAGGTGCTCGTGGGCGGTA
GAGGCCTGGCCGGTGGAGTAAAGAAGGCTAGTAACCTGGAGGAGGCCCTTACGAAGGCGAGGGAGCTCTTCTCGATGAGC
ATTAAGGGTGAGAGGGTTGAAAAAATACTGGTGGAGGAGGCTGTGTGTATCAGTAGAGAGCTTTACATGTCTCTCACTGT
TGATAGGGCTACTAGAAAACTAGTCTACCTTGCCTCAGGTATGGGCGGTGTTGAAATAGAGGAGCTAGCTAGAAAACACC
CTGATAAAATACTCAGGATACCCGTAGACCCGTTCATAGGATATAGTGGCTACATGGCTAGGCATGCACTTGGGTTCCTT
GGTCTTCAATGGGATAAACTAGGACAGCTCGACAACATCATGAGAGCTATGTATAAAATAATGATTGACTATGACGCGGA
ACTAGTGGAGTTCAATCCCTTAGCCTACACGTGTGATGGGAGGCTTACAGCGCTGGATGCAAAGATAATCATAGATGATA
ACAGCTTATACAGGCACCCCGATCTTCAGCCTTTATACGGGAGGGATGCTACCCCCTATGAGAAAGTAGCTAAGCAACTC
GACTTCAATTATGTCGAGCTTGATGGAGACATAGGGGTGATAAGTAATGGAGCCGGGTTAACAATGGCCACCATGGACTC
GATTCTACATTATGGTGGGAGACCAGCCAACTTCCTCGATATTGGTGGGGGTGCTACGCGTGAGAGGGTCAGGGAGGCAG
TTAAAATAGTGGTCACCCATCCAAGGGTCAAGGCAGTGTTAGTCAATATATTTGGCGGTATAACCAGGTGCGATGAAGTG
GCCTCTGGAATCGTTGAAGCCCTAAGTGAAACCAAGGTGGCTAAACCCATCGTGGTTAGAATGCTTGGCACCAATGAGGA
GGAGGGCAGGAGGATACTTATTGAGCATGGTATAACTGTTTACACGGAGATGGATGAAGCAGTATTAAGGATTATCCAAT
TAGTCAGGGGGGTGGGCTGA

Upstream 100 bases:

>100_bases
TGTTGAGTCCTCTAAGAATGATATTATGGCTGGTAAAAGATCGGATCACACATGCGTGCTTTAAATCCTTGCCAAGTATC
TTAAACTATGGGGGTCCTGT

Downstream 100 bases:

>100_bases
AGATGGGTATAATAGTTGACTCAAGGACCAGGGTACTGGTTCAAGGGATAACAGGTAGGGAGGGTGGGTTCCACACGAAG
CTCATGCTGGAGTATGGTAC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKLYEYEGKEIARKYGIETPRGILATSVEDVDKAYRELNTGTVVLKSQVLVGGRGLAGGVKKASNLEEALTKARELFSMS
IKGERVEKILVEEAVCISRELYMSLTVDRATRKLVYLASGMGGVEIEELARKHPDKILRIPVDPFIGYSGYMARHALGFL
GLQWDKLGQLDNIMRAMYKIMIDYDAELVEFNPLAYTCDGRLTALDAKIIIDDNSLYRHPDLQPLYGRDATPYEKVAKQL
DFNYVELDGDIGVISNGAGLTMATMDSILHYGGRPANFLDIGGGATRERVREAVKIVVTHPRVKAVLVNIFGGITRCDEV
ASGIVEALSETKVAKPIVVRMLGTNEEEGRRILIEHGITVYTEMDEAVLRIIQLVRGVG

Sequences:

>Translated_379_residues
MKLYEYEGKEIARKYGIETPRGILATSVEDVDKAYRELNTGTVVLKSQVLVGGRGLAGGVKKASNLEEALTKARELFSMS
IKGERVEKILVEEAVCISRELYMSLTVDRATRKLVYLASGMGGVEIEELARKHPDKILRIPVDPFIGYSGYMARHALGFL
GLQWDKLGQLDNIMRAMYKIMIDYDAELVEFNPLAYTCDGRLTALDAKIIIDDNSLYRHPDLQPLYGRDATPYEKVAKQL
DFNYVELDGDIGVISNGAGLTMATMDSILHYGGRPANFLDIGGGATRERVREAVKIVVTHPRVKAVLVNIFGGITRCDEV
ASGIVEALSETKVAKPIVVRMLGTNEEEGRRILIEHGITVYTEMDEAVLRIIQLVRGVG
>Mature_379_residues
MKLYEYEGKEIARKYGIETPRGILATSVEDVDKAYRELNTGTVVLKSQVLVGGRGLAGGVKKASNLEEALTKARELFSMS
IKGERVEKILVEEAVCISRELYMSLTVDRATRKLVYLASGMGGVEIEELARKHPDKILRIPVDPFIGYSGYMARHALGFL
GLQWDKLGQLDNIMRAMYKIMIDYDAELVEFNPLAYTCDGRLTALDAKIIIDDNSLYRHPDLQPLYGRDATPYEKVAKQL
DFNYVELDGDIGVISNGAGLTMATMDSILHYGGRPANFLDIGGGATRERVREAVKIVVTHPRVKAVLVNIFGGITRCDEV
ASGIVEALSETKVAKPIVVRMLGTNEEEGRRILIEHGITVYTEMDEAVLRIIQLVRGVG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI157779135, Length=380, Percent_Identity=36.5789473684211, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=36.6412213740458, Blast_Score=242, Evalue=4e-64,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=37.0473537604457, Blast_Score=230, Evalue=2e-60,
Organism=Escherichia coli, GI1786948, Length=389, Percent_Identity=41.6452442159383, Blast_Score=285, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17567829, Length=392, Percent_Identity=36.2244897959184, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17539378, Length=391, Percent_Identity=34.5268542199489, Blast_Score=239, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6321683, Length=399, Percent_Identity=37.593984962406, Blast_Score=258, Evalue=9e-70,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=37.9220779220779, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=37.9220779220779, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI281361397, Length=402, Percent_Identity=36.81592039801, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI281361395, Length=402, Percent_Identity=36.81592039801, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI21356231, Length=385, Percent_Identity=34.5454545454545, Blast_Score=225, Evalue=3e-59,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_DESK1 (B8D5I6)

Other databases:

- EMBL:   CP001140
- RefSeq:   YP_002428734.1
- GeneID:   7171152
- GenomeReviews:   CP001140_GR
- KEGG:   dka:DKAM_1041
- HOGENOM:   HBG315432
- OMA:   LPIVVRM
- ProtClustDB:   CLSK2399504
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41956; Mature: 41956

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYEYEGKEIARKYGIETPRGILATSVEDVDKAYRELNTGTVVLKSQVLVGGRGLAGGV
CCCEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCH
KKASNLEEALTKARELFSMSIKGERVEKILVEEAVCISRELYMSLTVDRATRKLVYLASG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHEEEEEECC
MGGVEIEELARKHPDKILRIPVDPFIGYSGYMARHALGFLGLQWDKLGQLDNIMRAMYKI
CCCCCHHHHHHHCCCCEEEECCCHHCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHH
MIDYDAELVEFNPLAYTCDGRLTALDAKIIIDDNSLYRHPDLQPLYGRDATPYEKVAKQL
HHCCCCCEEEECCEEEEECCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHC
DFNYVELDGDIGVISNGAGLTMATMDSILHYGGRPANFLDIGGGATRERVREAVKIVVTH
CCCEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHEEEEC
PRVKAVLVNIFGGITRCDEVASGIVEALSETKVAKPIVVRMLGTNEEEGRRILIEHGITV
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCEEEEECCCEE
YTEMDEAVLRIIQLVRGVG
EEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLYEYEGKEIARKYGIETPRGILATSVEDVDKAYRELNTGTVVLKSQVLVGGRGLAGGV
CCCEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCH
KKASNLEEALTKARELFSMSIKGERVEKILVEEAVCISRELYMSLTVDRATRKLVYLASG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHEEEEEECC
MGGVEIEELARKHPDKILRIPVDPFIGYSGYMARHALGFLGLQWDKLGQLDNIMRAMYKI
CCCCCHHHHHHHCCCCEEEECCCHHCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHH
MIDYDAELVEFNPLAYTCDGRLTALDAKIIIDDNSLYRHPDLQPLYGRDATPYEKVAKQL
HHCCCCCEEEECCEEEEECCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHC
DFNYVELDGDIGVISNGAGLTMATMDSILHYGGRPANFLDIGGGATRERVREAVKIVVTH
CCCEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHEEEEC
PRVKAVLVNIFGGITRCDEVASGIVEALSETKVAKPIVVRMLGTNEEEGRRILIEHGITV
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCEEEEECCCEE
YTEMDEAVLRIIQLVRGVG
EEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA