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The map label for this gene is sucD2 [H]

Identifier: 218884351

GI number: 218884351

Start: 986741

End: 987616

Strand: Reverse

Name: sucD2 [H]

Synonym: DKAM_1040

Alternate gene names: 218884351

Gene position: 987616-986741 (Counterclockwise)

Preceding gene: 218884352

Following gene: 218884350

Centisome position: 72.34

GC content: 47.26

Gene sequence:

>876_bases
ATGGGTATAATAGTTGACTCAAGGACCAGGGTACTGGTTCAAGGGATAACAGGTAGGGAGGGTGGGTTCCACACGAAGCT
CATGCTGGAGTATGGTACCAAGATAGTTGCAGGTACCTCACCCGGTAAAGGGGGAACATATGTCCATGGGGTTCCAGTGT
ATAACTCTATAAATGAAGCCATTAGAGAGCAGGGGACTATTGATGCAAGTATAATATTTGTTCCAGCCAGGTTCGCCAGT
GACGCTGTCTACGAGGCAGTGGACAATGGTGTTAAAACCATAGTGGTTATCACAGAGGGCATACCTCTACACGACGAACT
CAGGTTTGTGAACTATGCTAGAAGCCGTTCTGTCACACTTATCGGACCTAATACACCTGGAATAATGACGGTTGGTGAGG
CAAAGCTAGGTATAATGCCATCGCATGTGTTTAAACCTGGTAGAATAGGCATTGTCTCAAGAAGCGGTACGTTAACATAC
GAGGTAGCTAGGGAGCTTATCAAACAGGGTTACGGGGTTTCGACAGTTCTGGGATTGGGTGGAGACCCGGTTACAGGGTT
AGACTTCATTGATGTATTCAAGATGTTCTCCAAAGATGATTCAACAGATGCAGTCGTGTTAATCGGGGAGATAGGCGGCG
ATGCTGAGGAGAGGTTTGCTAGATTCTACAGTCAGTATGATGGGAGGAAACCGGTTGTTGCATATATAGCTGGTAGAACC
GCCCCACCAGGGAAAAGGATGGGTCACGCCGGTGCAATAATATCGATGGGTATAGGCGACTATGCTTCCAAGAGGAGTAG
CCTTGAAGAAGCCGGAATACCTGTAGCGGATACCCCGTCACAGATACACCAGTTATTAAGCAAGATCCTTGTATAG

Upstream 100 bases:

>100_bases
AGGGCAGGAGGATACTTATTGAGCATGGTATAACTGTTTACACGGAGATGGATGAAGCAGTATTAAGGATTATCCAATTA
GTCAGGGGGGTGGGCTGAAG

Downstream 100 bases:

>100_bases
GGTTCACCCAAGGTATTTTTAAGGAAAACCTCCTTGGAATACATGATGTGTCATGCTGTTTTTGTTTTATAGTTTGGAGT
TTTATAGGCTGCTTAATGTT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha 2; SCS-alpha 2 [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MGIIVDSRTRVLVQGITGREGGFHTKLMLEYGTKIVAGTSPGKGGTYVHGVPVYNSINEAIREQGTIDASIIFVPARFAS
DAVYEAVDNGVKTIVVITEGIPLHDELRFVNYARSRSVTLIGPNTPGIMTVGEAKLGIMPSHVFKPGRIGIVSRSGTLTY
EVARELIKQGYGVSTVLGLGGDPVTGLDFIDVFKMFSKDDSTDAVVLIGEIGGDAEERFARFYSQYDGRKPVVAYIAGRT
APPGKRMGHAGAIISMGIGDYASKRSSLEEAGIPVADTPSQIHQLLSKILV

Sequences:

>Translated_291_residues
MGIIVDSRTRVLVQGITGREGGFHTKLMLEYGTKIVAGTSPGKGGTYVHGVPVYNSINEAIREQGTIDASIIFVPARFAS
DAVYEAVDNGVKTIVVITEGIPLHDELRFVNYARSRSVTLIGPNTPGIMTVGEAKLGIMPSHVFKPGRIGIVSRSGTLTY
EVARELIKQGYGVSTVLGLGGDPVTGLDFIDVFKMFSKDDSTDAVVLIGEIGGDAEERFARFYSQYDGRKPVVAYIAGRT
APPGKRMGHAGAIISMGIGDYASKRSSLEEAGIPVADTPSQIHQLLSKILV
>Mature_290_residues
GIIVDSRTRVLVQGITGREGGFHTKLMLEYGTKIVAGTSPGKGGTYVHGVPVYNSINEAIREQGTIDASIIFVPARFASD
AVYEAVDNGVKTIVVITEGIPLHDELRFVNYARSRSVTLIGPNTPGIMTVGEAKLGIMPSHVFKPGRIGIVSRSGTLTYE
VARELIKQGYGVSTVLGLGGDPVTGLDFIDVFKMFSKDDSTDAVVLIGEIGGDAEERFARFYSQYDGRKPVVAYIAGRTA
PPGKRMGHAGAIISMGIGDYASKRSSLEEAGIPVADTPSQIHQLLSKILV

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=284, Percent_Identity=50.3521126760563, Blast_Score=242, Evalue=3e-64,
Organism=Homo sapiens, GI38569423, Length=251, Percent_Identity=28.2868525896414, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI38569421, Length=251, Percent_Identity=28.2868525896414, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1786949, Length=290, Percent_Identity=50, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI1786513, Length=241, Percent_Identity=24.4813278008299, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=282, Percent_Identity=48.936170212766, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=47.098976109215, Blast_Score=250, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI17557344, Length=268, Percent_Identity=29.1044776119403, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17551266, Length=275, Percent_Identity=29.4545454545455, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=41.4383561643836, Blast_Score=226, Evalue=2e-60,
Organism=Drosophila melanogaster, GI21356559, Length=286, Percent_Identity=45.1048951048951, Blast_Score=246, Evalue=9e-66,
Organism=Drosophila melanogaster, GI28574296, Length=290, Percent_Identity=46.551724137931, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI281363475, Length=253, Percent_Identity=29.2490118577075, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281363473, Length=253, Percent_Identity=29.2490118577075, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281363477, Length=253, Percent_Identity=29.2490118577075, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31000; Mature: 30869

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIIVDSRTRVLVQGITGREGGFHTKLMLEYGTKIVAGTSPGKGGTYVHGVPVYNSINEA
CCEEECCCCEEEEEECCCCCCCCEEEEEEECCCEEEEECCCCCCCCEEEEECCHHHHHHH
IREQGTIDASIIFVPARFASDAVYEAVDNGVKTIVVITEGIPLHDELRFVNYARSRSVTL
HHHCCCCCEEEEEEECHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEE
IGPNTPGIMTVGEAKLGIMPSHVFKPGRIGIVSRSGTLTYEVARELIKQGYGVSTVLGLG
ECCCCCCEEEECCCEECCCHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECC
GDPVTGLDFIDVFKMFSKDDSTDAVVLIGEIGGDAEERFARFYSQYDGRKPVVAYIAGRT
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCC
APPGKRMGHAGAIISMGIGDYASKRSSLEEAGIPVADTPSQIHQLLSKILV
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
GIIVDSRTRVLVQGITGREGGFHTKLMLEYGTKIVAGTSPGKGGTYVHGVPVYNSINEA
CEEECCCCEEEEEECCCCCCCCEEEEEEECCCEEEEECCCCCCCCEEEEECCHHHHHHH
IREQGTIDASIIFVPARFASDAVYEAVDNGVKTIVVITEGIPLHDELRFVNYARSRSVTL
HHHCCCCCEEEEEEECHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEE
IGPNTPGIMTVGEAKLGIMPSHVFKPGRIGIVSRSGTLTYEVARELIKQGYGVSTVLGLG
ECCCCCCEEEECCCEECCCHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECC
GDPVTGLDFIDVFKMFSKDDSTDAVVLIGEIGGDAEERFARFYSQYDGRKPVVAYIAGRT
CCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCC
APPGKRMGHAGAIISMGIGDYASKRSSLEEAGIPVADTPSQIHQLLSKILV
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]