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The map label for this gene is xerC

Identifier: 218710942

GI number: 218710942

Start: 3192689

End: 3193621

Strand: Reverse

Name: xerC

Synonym: VS_3045

Alternate gene names: 218710942

Gene position: 3193621-3192689 (Counterclockwise)

Preceding gene: 218710943

Following gene: 218710941

Centisome position: 96.8

GC content: 48.45

Gene sequence:

>933_bases
ATGAGCCTAGAGCCCAAAATACCTCTTCCTAATAGCCTTCAAAAGCCGCTCTCTCGCTTCTATGAATATCTTAGAAGTGA
GAAGGGACTCAGCTTACACACCCAACGTAACTACAAACAACAACTTGAAACCATGGCCGCTCATTTAGTCACTCTTGGAC
TAAAGGATTGGTCTCAAGTCGATGCGGCGTGGGTAAGACAACTTGCAAGTAAAGGCATGCGCGAAGGAATGAAAGCGAGC
AGTATTGCGACTCGCTTATCGTCACTGCGCAGCTTCTTTGATTTCCTTGTCTTGCGTGGCGAAATGACCGCCAATCCTGC
TAAAGGGGTTTCAGCACCTCGCAAACAGCGTCCTTTGCCTAAAAACCTCGATGTTGATGAAGTCGGGCAGCTGCTTGACG
TAAACGAGGATGACCCGCTATCGATTCGTGACCGAGCGATGATGGAAGTGATGTATGGTGCTGGACTACGACTGGCTGAG
CTGGTCGGTATCAATCTTAAAGATGTATTGGGTCGACAAGGCGAAATCCGAGTGATTGGTAAAGGCGACAAAGAACGCAA
AGCGCCTTTTTCTGGTTTAGCGAAAGAGTGGGTTGATAAATGGCTCAAAGTTCGTGGTGCACTAGCTTCGCCGGGTGAAA
CCGCTCTGTTTGTCTCTAAACTCGGGACTCGTATCTCTCATCGCAGCGTGCAAAAGCGCATGGAAGAGTGGGGCAAGAAG
CAATCTGTCGCGAGTCACATCAGCCCGCATAAACTGCGTCACTCCTTTGCAACGCATGTACTGGAGTCGAGCCAAAACCT
TCGTGCGGTTCAAGAGTTGCTCGGGCATGAAAACATCTCGACAACCCAAGTGTACACTCACTTAGATTTCCAACATTTAG
CACAAGCTTATGACCAAGCTCATCCAAGAGCTCGTAAGAAGAATAAAGATTAG

Upstream 100 bases:

>100_bases
GATGGCGGACACTTCCAGCCTCATATGGACACGCTCTTTTTACGCCATTTAGCACTTGTTGTCGCTCATTTGGCGGACAC
CTTACCTTGGCAGATAAATA

Downstream 100 bases:

>100_bases
ATTAAAGGTTTAACTATGCGAATTTATCGAGGGTTAAAGCCCATCAAAGCCATGACCTTTGATTTGGATGATACCTTGTA
CGACAACTGGCCTGTGATCA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSLEPKIPLPNSLQKPLSRFYEYLRSEKGLSLHTQRNYKQQLETMAAHLVTLGLKDWSQVDAAWVRQLASKGMREGMKAS
SIATRLSSLRSFFDFLVLRGEMTANPAKGVSAPRKQRPLPKNLDVDEVGQLLDVNEDDPLSIRDRAMMEVMYGAGLRLAE
LVGINLKDVLGRQGEIRVIGKGDKERKAPFSGLAKEWVDKWLKVRGALASPGETALFVSKLGTRISHRSVQKRMEEWGKK
QSVASHISPHKLRHSFATHVLESSQNLRAVQELLGHENISTTQVYTHLDFQHLAQAYDQAHPRARKKNKD

Sequences:

>Translated_310_residues
MSLEPKIPLPNSLQKPLSRFYEYLRSEKGLSLHTQRNYKQQLETMAAHLVTLGLKDWSQVDAAWVRQLASKGMREGMKAS
SIATRLSSLRSFFDFLVLRGEMTANPAKGVSAPRKQRPLPKNLDVDEVGQLLDVNEDDPLSIRDRAMMEVMYGAGLRLAE
LVGINLKDVLGRQGEIRVIGKGDKERKAPFSGLAKEWVDKWLKVRGALASPGETALFVSKLGTRISHRSVQKRMEEWGKK
QSVASHISPHKLRHSFATHVLESSQNLRAVQELLGHENISTTQVYTHLDFQHLAQAYDQAHPRARKKNKD
>Mature_309_residues
SLEPKIPLPNSLQKPLSRFYEYLRSEKGLSLHTQRNYKQQLETMAAHLVTLGLKDWSQVDAAWVRQLASKGMREGMKASS
IATRLSSLRSFFDFLVLRGEMTANPAKGVSAPRKQRPLPKNLDVDEVGQLLDVNEDDPLSIRDRAMMEVMYGAGLRLAEL
VGINLKDVLGRQGEIRVIGKGDKERKAPFSGLAKEWVDKWLKVRGALASPGETALFVSKLGTRISHRSVQKRMEEWGKKQ
SVASHISPHKLRHSFATHVLESSQNLRAVQELLGHENISTTQVYTHLDFQHLAQAYDQAHPRARKKNKD

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=294, Percent_Identity=56.1224489795918, Blast_Score=337, Evalue=4e-94,
Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=35.958904109589, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1790768, Length=151, Percent_Identity=27.1523178807947, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_VIBSL (B7VMD2)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418563.1
- GeneID:   7162509
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_3045
- HOGENOM:   HBG727654
- OMA:   TTEGIRD
- ProtClustDB:   PRK00236
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 34991; Mature: 34860

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: ACT_SITE 157-157 ACT_SITE 181-181 ACT_SITE 250-250 ACT_SITE 253-253 ACT_SITE 276-276 ACT_SITE 285-285

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEPKIPLPNSLQKPLSRFYEYLRSEKGLSLHTQRNYKQQLETMAAHLVTLGLKDWSQV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
DAAWVRQLASKGMREGMKASSIATRLSSLRSFFDFLVLRGEMTANPAKGVSAPRKQRPLP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCC
KNLDVDEVGQLLDVNEDDPLSIRDRAMMEVMYGAGLRLAELVGINLKDVLGRQGEIRVIG
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHCCCCCEEEEC
KGDKERKAPFSGLAKEWVDKWLKVRGALASPGETALFVSKLGTRISHRSVQKRMEEWGKK
CCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSVASHISPHKLRHSFATHVLESSQNLRAVQELLGHENISTTQVYTHLDFQHLAQAYDQA
HHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHH
HPRARKKNKD
CCHHHCCCCC
>Mature Secondary Structure 
SLEPKIPLPNSLQKPLSRFYEYLRSEKGLSLHTQRNYKQQLETMAAHLVTLGLKDWSQV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
DAAWVRQLASKGMREGMKASSIATRLSSLRSFFDFLVLRGEMTANPAKGVSAPRKQRPLP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCC
KNLDVDEVGQLLDVNEDDPLSIRDRAMMEVMYGAGLRLAELVGINLKDVLGRQGEIRVIG
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHCCCCCEEEEC
KGDKERKAPFSGLAKEWVDKWLKVRGALASPGETALFVSKLGTRISHRSVQKRMEEWGKK
CCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSVASHISPHKLRHSFATHVLESSQNLRAVQELLGHENISTTQVYTHLDFQHLAQAYDQA
HHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHH
HPRARKKNKD
CCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA