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The map label for this gene is 218710857

Identifier: 218710857

GI number: 218710857

Start: 3099571

End: 3100203

Strand: Direct

Name: 218710857

Synonym: VS_2941

Alternate gene names: NA

Gene position: 3099571-3100203 (Clockwise)

Preceding gene: 218710856

Following gene: 218710858

Centisome position: 93.95

GC content: 45.02

Gene sequence:

>633_bases
ATGAATAGATTGGTTCGTTATTACTGGCATCATAAACTCAAAGGCTCTACTTATCAGCCTCTGTTTACTGCGCCTGCTAA
TCACGAATACGTATCTCTCGATTGTGAAACCACCAGCCTCGACCCCAATCAGGCAGAATTAGTCACCATTGCCGCAACCA
AGATCATCGGCAACCGAATCATTACCAGCCAACCTTTTGAAGTCCGATTGCGCGCCCCTCAATCGCTCGATTGCAATTCA
ATAAAAATCCACCGTATTCGCCATCAAGATCTAAAGCACGGCATCGAAGAAAAACAGGCTTTAATCGAGCTACTGAACTT
CATTGGAAATCGTCCTTTAGTCGGCTATCACATCCGCTATGATAAAAAAATCCTCGATCGCGCCTGTTTAAAACAGCTTG
GATTTCCACTGCCTAACCGATTAGTCGAAGTAAGCCAACTTTATCAAGACAAGCTCGAAAGGCAGCTGCCCAATGCCTAT
TTTGATCTCAGTATGGACGCCATCTGTCGCCAGCTCGATTTACCTATCCCCGTCAATAAACATGATGCATTACAAGACGC
TATCTCCGCAGCCCTGATCTTTGTTCGCCTGAAACATGGTGATCTGCCCCGTTTCAACTCTTCTTATTCTTAA

Upstream 100 bases:

>100_bases
GAGCAGACAGAGACTTACTTCGCCATAGCTTGCATGTGGTCAAAAAATTCAAGCAATGGCTTGGCTACCACTATCAGATA
CGGGATTAGGCGATTGAACG

Downstream 100 bases:

>100_bases
TTCAACCACTGGCGCTTCACATAGAGAGCAACATCTCAAAAATGAACTTAACTCGCTATTTTGTAAGTGAAAAGCAGCGT
CTCATCCTAAAGTCTAATTG

Product: DNA polymerase III subunit epsilon

Products: diphosphate; DNAn+1

Alternate protein names: DNA Polymerase III Epsilon Subunit; Exonuclease RNAse T And DNA Polymerase III; Exonuclease; Exonuclease Family Protein; Exonuclease RNAase T And DNA Polymerase III; DNA Polymerase IIIsubunit Epsilon; Exonuclease Superfamily

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MNRLVRYYWHHKLKGSTYQPLFTAPANHEYVSLDCETTSLDPNQAELVTIAATKIIGNRIITSQPFEVRLRAPQSLDCNS
IKIHRIRHQDLKHGIEEKQALIELLNFIGNRPLVGYHIRYDKKILDRACLKQLGFPLPNRLVEVSQLYQDKLERQLPNAY
FDLSMDAICRQLDLPIPVNKHDALQDAISAALIFVRLKHGDLPRFNSSYS

Sequences:

>Translated_210_residues
MNRLVRYYWHHKLKGSTYQPLFTAPANHEYVSLDCETTSLDPNQAELVTIAATKIIGNRIITSQPFEVRLRAPQSLDCNS
IKIHRIRHQDLKHGIEEKQALIELLNFIGNRPLVGYHIRYDKKILDRACLKQLGFPLPNRLVEVSQLYQDKLERQLPNAY
FDLSMDAICRQLDLPIPVNKHDALQDAISAALIFVRLKHGDLPRFNSSYS
>Mature_210_residues
MNRLVRYYWHHKLKGSTYQPLFTAPANHEYVSLDCETTSLDPNQAELVTIAATKIIGNRIITSQPFEVRLRAPQSLDCNS
IKIHRIRHQDLKHGIEEKQALIELLNFIGNRPLVGYHIRYDKKILDRACLKQLGFPLPNRLVEVSQLYQDKLERQLPNAY
FDLSMDAICRQLDLPIPVNKHDALQDAISAALIFVRLKHGDLPRFNSSYS

Specific function: Unknown

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 24241; Mature: 24241

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLVRYYWHHKLKGSTYQPLFTAPANHEYVSLDCETTSLDPNQAELVTIAATKIIGNRI
CCCHHHHHHHHHCCCCCCCCEEECCCCCCEEEEECEECCCCCCCHHEEEHHHHHHHHCCC
ITSQPFEVRLRAPQSLDCNSIKIHRIRHQDLKHGIEEKQALIELLNFIGNRPLVGYHIRY
CCCCCCEEEEECCCCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEEH
DKKILDRACLKQLGFPLPNRLVEVSQLYQDKLERQLPNAYFDLSMDAICRQLDLPIPVNK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCCCCCH
HDALQDAISAALIFVRLKHGDLPRFNSSYS
HHHHHHHHHHHHHHEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNRLVRYYWHHKLKGSTYQPLFTAPANHEYVSLDCETTSLDPNQAELVTIAATKIIGNRI
CCCHHHHHHHHHCCCCCCCCEEECCCCCCEEEEECEECCCCCCCHHEEEHHHHHHHHCCC
ITSQPFEVRLRAPQSLDCNSIKIHRIRHQDLKHGIEEKQALIELLNFIGNRPLVGYHIRY
CCCCCCEEEEECCCCCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEEH
DKKILDRACLKQLGFPLPNRLVEVSQLYQDKLERQLPNAYFDLSMDAICRQLDLPIPVNK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCCCCCH
HDALQDAISAALIFVRLKHGDLPRFNSSYS
HHHHHHHHHHHHHHEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA