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The map label for this gene is rpfG [H]

Identifier: 218710644

GI number: 218710644

Start: 2892329

End: 2893582

Strand: Reverse

Name: rpfG [H]

Synonym: VS_2723

Alternate gene names: 218710644

Gene position: 2893582-2892329 (Counterclockwise)

Preceding gene: 218710645

Following gene: 218710643

Centisome position: 87.7

GC content: 39.31

Gene sequence:

>1254_bases
ATGGGCAGCATAAAGATTACTGTAGATCGCATCCAGCCCGGCCTACACATACGACTCCCCCTAAAATGGAACGAACACCC
ATTTTTATTCAACAGCTTCAAAATAAAAGATGACGATCAAGTGAAAATAATTCGGCATCTTGGGATTAAGCATGTCTATA
TAAATCTAAGTCAAAGCGATACTGCACCTTTACCTTCTAATCACGAGATAGATAAAGGGGCCGATTCAGATCTACAGATA
AGCCTTGAAACTGAAAGGATGTGGAAAGATAAGCATGAACGTATCGAAACCCTAAGCTCTTACCGTCGTAGAGTCAGTCA
TTGCGAGAAAGAGTTCGAGCGCTCGCTTGCTCGAATGCGTTCAGTAATGACAAAAATTCGTAACCGACCTATAGATGCGG
TAGGAGAGGTTAAAAGTCTAGTTGATGATATTGTTGAAATACTGGCAAGTGACGATAGCGTTACCTTGCATCTTATGAAT
GCTAAAGCTGACTTTGAAGACATTTACTTTCATACATTAAATGTCTCTGTCGTTGCGTTAATGATAGGTAAAGCTAAAGG
CTACAATACTCAACAATTGAAAGCGCTTTCTTTTGCTGCTTTGTTCCATGATGTAGGAAAGATCAAAATACCAGCTGCAA
TACTTAGAAAGCAGAGTACGCTGACAGCACCGGAAGAGAATTACCTAAAACTTCATACGAAATATGGTGCTGATATTGTC
TCTGGAATTGATGACTTTCCTGAAAGTGCCAAAAAAGTAATCGTTCAACATCATGAAATGAATGATGGCTCTGGTTATCC
TGAAGGCTTAAAAGAAGAAGAGATAGATGAACTAACCAAAATAGTTTCAGTGGCTAACGCATTCGATAATCTTTGTCATG
GTAAAGCGCAATCTCAACAAATGATCCCATACTTGGCATTGTCCCACTTATATAAGAACTGCAAACATCTATATAGTCAG
GATAATTTGAGTCTATTGGTTAAGTTCATGGGAGTCTATCCGCCGGGTACTGTCGTGCAGCTTTCCAATGAATCAATTGG
AATCGTGATTTCGGTTAATGCCAAACATATGCTTTATCCGAACGTATTGATCTATGATCCTAGCGTTCCAAGAACCCAAG
CCCCGATCATTGACCTATTTACTAAAGAGATAAAAATTGTCAATGCAGTTCATCCAAGCAAGTTACCGGAGCAAGTTAGA
GAATATCTAAACCCTAGGGCTCGTTTATCTTACTTTTTTGATAATGGTGAGTAG

Upstream 100 bases:

>100_bases
TTGTGATTCTTTAAGTTGAACCTGTGAAATTGGATAGTGAAATTCCCGTGTGGTTTTATTAGAATTATAAATATAGATTA
TTAATCAATATTATATAAAT

Downstream 100 bases:

>100_bases
TTATCCACAGGTTCTTGTGGGTAGTTTGTTCGAAACTTGGGTTGAAAGTTGTATAAATAAGCCCTTGGTTGAAATGTCTT
CACTTAACCTCTTTTTTAAA

Product: HD-GYP domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MGSIKITVDRIQPGLHIRLPLKWNEHPFLFNSFKIKDDDQVKIIRHLGIKHVYINLSQSDTAPLPSNHEIDKGADSDLQI
SLETERMWKDKHERIETLSSYRRRVSHCEKEFERSLARMRSVMTKIRNRPIDAVGEVKSLVDDIVEILASDDSVTLHLMN
AKADFEDIYFHTLNVSVVALMIGKAKGYNTQQLKALSFAALFHDVGKIKIPAAILRKQSTLTAPEENYLKLHTKYGADIV
SGIDDFPESAKKVIVQHHEMNDGSGYPEGLKEEEIDELTKIVSVANAFDNLCHGKAQSQQMIPYLALSHLYKNCKHLYSQ
DNLSLLVKFMGVYPPGTVVQLSNESIGIVISVNAKHMLYPNVLIYDPSVPRTQAPIIDLFTKEIKIVNAVHPSKLPEQVR
EYLNPRARLSYFFDNGE

Sequences:

>Translated_417_residues
MGSIKITVDRIQPGLHIRLPLKWNEHPFLFNSFKIKDDDQVKIIRHLGIKHVYINLSQSDTAPLPSNHEIDKGADSDLQI
SLETERMWKDKHERIETLSSYRRRVSHCEKEFERSLARMRSVMTKIRNRPIDAVGEVKSLVDDIVEILASDDSVTLHLMN
AKADFEDIYFHTLNVSVVALMIGKAKGYNTQQLKALSFAALFHDVGKIKIPAAILRKQSTLTAPEENYLKLHTKYGADIV
SGIDDFPESAKKVIVQHHEMNDGSGYPEGLKEEEIDELTKIVSVANAFDNLCHGKAQSQQMIPYLALSHLYKNCKHLYSQ
DNLSLLVKFMGVYPPGTVVQLSNESIGIVISVNAKHMLYPNVLIYDPSVPRTQAPIIDLFTKEIKIVNAVHPSKLPEQVR
EYLNPRARLSYFFDNGE
>Mature_416_residues
GSIKITVDRIQPGLHIRLPLKWNEHPFLFNSFKIKDDDQVKIIRHLGIKHVYINLSQSDTAPLPSNHEIDKGADSDLQIS
LETERMWKDKHERIETLSSYRRRVSHCEKEFERSLARMRSVMTKIRNRPIDAVGEVKSLVDDIVEILASDDSVTLHLMNA
KADFEDIYFHTLNVSVVALMIGKAKGYNTQQLKALSFAALFHDVGKIKIPAAILRKQSTLTAPEENYLKLHTKYGADIVS
GIDDFPESAKKVIVQHHEMNDGSGYPEGLKEEEIDELTKIVSVANAFDNLCHGKAQSQQMIPYLALSHLYKNCKHLYSQD
NLSLLVKFMGVYPPGTVVQLSNESIGIVISVNAKHMLYPNVLIYDPSVPRTQAPIIDLFTKEIKIVNAVHPSKLPEQVRE
YLNPRARLSYFFDNGE

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG2206

COG function: function code T; HD-GYP domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 47322; Mature: 47191

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSIKITVDRIQPGLHIRLPLKWNEHPFLFNSFKIKDDDQVKIIRHLGIKHVYINLSQSD
CCCEEEEEEECCCCEEEEEEEEECCCCCEEEEEEECCCCHHHHHHHCCEEEEEEEECCCC
TAPLPSNHEIDKGADSDLQISLETERMWKDKHERIETLSSYRRRVSHCEKEFERSLARMR
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVMTKIRNRPIDAVGEVKSLVDDIVEILASDDSVTLHLMNAKADFEDIYFHTLNVSVVAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHEEEEEHHHHEEH
MIGKAKGYNTQQLKALSFAALFHDVGKIKIPAAILRKQSTLTAPEENYLKLHTKYGADIV
HHHCCCCCCHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCCCCCCEEEEEHHCCHHH
SGIDDFPESAKKVIVQHHEMNDGSGYPEGLKEEEIDELTKIVSVANAFDNLCHGKAQSQQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
MIPYLALSHLYKNCKHLYSQDNLSLLVKFMGVYPPGTVVQLSNESIGIVISVNAKHMLYP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCEEECC
NVLIYDPSVPRTQAPIIDLFTKEIKIVNAVHPSKLPEQVREYLNPRARLSYFFDNGE
EEEEECCCCCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHCCCCCEEEEEECCCC
>Mature Secondary Structure 
GSIKITVDRIQPGLHIRLPLKWNEHPFLFNSFKIKDDDQVKIIRHLGIKHVYINLSQSD
CCEEEEEEECCCCEEEEEEEEECCCCCEEEEEEECCCCHHHHHHHCCEEEEEEEECCCC
TAPLPSNHEIDKGADSDLQISLETERMWKDKHERIETLSSYRRRVSHCEKEFERSLARMR
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVMTKIRNRPIDAVGEVKSLVDDIVEILASDDSVTLHLMNAKADFEDIYFHTLNVSVVAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHEEEEEHHHHEEH
MIGKAKGYNTQQLKALSFAALFHDVGKIKIPAAILRKQSTLTAPEENYLKLHTKYGADIV
HHHCCCCCCHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCCCCCCEEEEEHHCCHHH
SGIDDFPESAKKVIVQHHEMNDGSGYPEGLKEEEIDELTKIVSVANAFDNLCHGKAQSQQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
MIPYLALSHLYKNCKHLYSQDNLSLLVKFMGVYPPGTVVQLSNESIGIVISVNAKHMLYP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCEEECC
NVLIYDPSVPRTQAPIIDLFTKEIKIVNAVHPSKLPEQVREYLNPRARLSYFFDNGE
EEEEECCCCCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]