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The map label for this gene is cobIJ [H]

Identifier: 218710610

GI number: 218710610

Start: 2851025

End: 2851840

Strand: Direct

Name: cobIJ [H]

Synonym: VS_2664

Alternate gene names: 218710610

Gene position: 2851025-2851840 (Clockwise)

Preceding gene: 218710609

Following gene: 218710611

Centisome position: 86.41

GC content: 45.1

Gene sequence:

>816_bases
ATGAAATTAGGAACTATGTACGCAATTGGTGTCGGCACTGGAGACCCAGAATTATTAACACTTAAAGCTCACCGACTACT
CAGCACCGTCGACATTGTCGCGTTTCCAGAAAAAGACGCGGGCAGTAACCACTCTTTTGCTCAACAAATTGCAGCGGGTT
CTGTTAGCCCTGAAAGCATGAAAGGCGAATACCTATTTTTGCACTTCCCAATGACGCGTGACCCAAGCATCAACGTTCCT
GCATGGCGTAAAGCCGCCGTCACAATTGTTGAACTATTAAAGCAAGGTAAAGACGTGGCATTTGCAACCGAAGGTGATCC
ATCGGTTTACAGCACATGGGCATACATCCAAGAAGAACTGACAGAGCTACTTCCTGAACTTGATCCGGTGATCATTCCGG
GTATCACTTCAGTTACCGCTATTCCATCACAAACAAAAATTCCACTTGCTGACGGTCAGGAGCGTTTTTGTGTTGTACCT
GCGACATGGGGTATCGAGTGTTTAGAAAAGCTAGTCGAAGATTTTGACACCATCATGTTAATCAAAGCAGGTCGCGTTAT
CCCTAAGCTGATCACTCAACTTGAGTCGATGAGTATGTTGGATTGTGCAACCTACGTATCGCATGCCACCACAGAGAAAC
AAGAGCTTTACTCTGACCTACGTGATGTACCGAATGAAAACCGCTACTTCTCTATGGTTCAGCTTTCAGTTCGCGCTCGT
CGTGGCGTACTACGTGGTACTAATGAATCAAAGAAATGTGCCGTTCTTGATGATGGTAAAGATGACATCAATAAAACTAA
TAGCGGTAAAGCGTAA

Upstream 100 bases:

>100_bases
ATTTATTTTTACCAAGCCGTTTATTCAGAAATAAGCGCTTAATTTTTTAATTAAGCGCCACTCAACATATTAAATAAAAA
CATAATTAGAGAAAGCACAG

Downstream 100 bases:

>100_bases
TGAAAATAGCCATTTATGCCATCACGCTACACGGAGCAAGGCAAGCCAAACGCTTAGCTAAAACGTTTCCGTTTGCTGAT
GTCTTTATTGCACCAGTTGG

Product: precorrin-2 C-20 methlytransferase

Products: NA

Alternate protein names: Precorrin-2 C(20)-methyltransferase; S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT; Precorrin-3B C17-methyltransferase; S-adenosyl-L-methionine--precorrin-3B methyltransferase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKLGTMYAIGVGTGDPELLTLKAHRLLSTVDIVAFPEKDAGSNHSFAQQIAAGSVSPESMKGEYLFLHFPMTRDPSINVP
AWRKAAVTIVELLKQGKDVAFATEGDPSVYSTWAYIQEELTELLPELDPVIIPGITSVTAIPSQTKIPLADGQERFCVVP
ATWGIECLEKLVEDFDTIMLIKAGRVIPKLITQLESMSMLDCATYVSHATTEKQELYSDLRDVPNENRYFSMVQLSVRAR
RGVLRGTNESKKCAVLDDGKDDINKTNSGKA

Sequences:

>Translated_271_residues
MKLGTMYAIGVGTGDPELLTLKAHRLLSTVDIVAFPEKDAGSNHSFAQQIAAGSVSPESMKGEYLFLHFPMTRDPSINVP
AWRKAAVTIVELLKQGKDVAFATEGDPSVYSTWAYIQEELTELLPELDPVIIPGITSVTAIPSQTKIPLADGQERFCVVP
ATWGIECLEKLVEDFDTIMLIKAGRVIPKLITQLESMSMLDCATYVSHATTEKQELYSDLRDVPNENRYFSMVQLSVRAR
RGVLRGTNESKKCAVLDDGKDDINKTNSGKA
>Mature_271_residues
MKLGTMYAIGVGTGDPELLTLKAHRLLSTVDIVAFPEKDAGSNHSFAQQIAAGSVSPESMKGEYLFLHFPMTRDPSINVP
AWRKAAVTIVELLKQGKDVAFATEGDPSVYSTWAYIQEELTELLPELDPVIIPGITSVTAIPSQTKIPLADGQERFCVVP
ATWGIECLEKLVEDFDTIMLIKAGRVIPKLITQLESMSMLDCATYVSHATTEKQELYSDLRDVPNENRYFSMVQLSVRAR
RGVLRGTNESKKCAVLDDGKDDINKTNSGKA

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR006364
- InterPro:   IPR006363
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130; =2.1.1.131 [H]

Molecular weight: Translated: 29780; Mature: 29780

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGTMYAIGVGTGDPELLTLKAHRLLSTVDIVAFPEKDAGSNHSFAQQIAAGSVSPESM
CCCCEEEEEEECCCCCCEEEHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHCCCCCHHHC
KGEYLFLHFPMTRDPSINVPAWRKAAVTIVELLKQGKDVAFATEGDPSVYSTWAYIQEEL
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
TELLPELDPVIIPGITSVTAIPSQTKIPLADGQERFCVVPATWGIECLEKLVEDFDTIML
HHHHHHCCCEEECCCCCEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHEEE
IKAGRVIPKLITQLESMSMLDCATYVSHATTEKQELYSDLRDVPNENRYFSMVQLSVRAR
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHH
RGVLRGTNESKKCAVLDDGKDDINKTNSGKA
HHHHCCCCCCCEEEEECCCHHHCCCCCCCCC
>Mature Secondary Structure
MKLGTMYAIGVGTGDPELLTLKAHRLLSTVDIVAFPEKDAGSNHSFAQQIAAGSVSPESM
CCCCEEEEEEECCCCCCEEEHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHCCCCCHHHC
KGEYLFLHFPMTRDPSINVPAWRKAAVTIVELLKQGKDVAFATEGDPSVYSTWAYIQEEL
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
TELLPELDPVIIPGITSVTAIPSQTKIPLADGQERFCVVPATWGIECLEKLVEDFDTIML
HHHHHHCCCEEECCCCCEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHEEE
IKAGRVIPKLITQLESMSMLDCATYVSHATTEKQELYSDLRDVPNENRYFSMVQLSVRAR
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHH
RGVLRGTNESKKCAVLDDGKDDINKTNSGKA
HHHHCCCCCCCEEEEECCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]