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The map label for this gene is gluQ [H]

Identifier: 218710490

GI number: 218710490

Start: 2718917

End: 2719819

Strand: Direct

Name: gluQ [H]

Synonym: VS_2529

Alternate gene names: 218710490

Gene position: 2718917-2719819 (Clockwise)

Preceding gene: 218710489

Following gene: 218710491

Centisome position: 82.41

GC content: 45.29

Gene sequence:

>903_bases
ATGAATTATATCGGACGCTTTGCACCATCACCGTCAGGTCCTCTTCATTTTGGCTCACTGGTTGCTGCTCTTGGTAGCTA
CTTTCAAGCGAAATCTAACCAAGGACAATGGTTAGTTCGTATGGAAGACCTCGATCCACCAAGAGAAATGGCTGGCGCTG
CAGACCTCATTCTTAAGACGCTTGAGGCTTACCACCTGTATTGGGACGGTGAAGTCGTTTATCAAAGCCAGCGTCATGAC
CTATATCAAGCTCAAATTGATCAATGGGTCACTGACAATCAGGCCTACTACTGTCAATGTACCCGTAAGCAGATAAAGTC
CTTGGGTGGGTTTTATAGTGGCCGCTGCCGAGACAAAGGTTTGGTTGATTCAGGCGAACAGGCGGTGCGCTTGTGTATGG
ACTTTCCCATCGAGTCCTTTGACGATGTTCGTCACGGCACGATTCAAATTCCCAAAGCATTGGCTGAAGAAGATTTTATT
ATCAAACGCAGAGATGGGTTGTTTGCCTATAACTTGGCAGTTGTCCTTGATGACATCGAACAAGGGGTAACAGAAGTCGT
TAGAGGTGCAGATCTGATAGAACCAACAGGTCGACAAATCAGTTTGTATAAGACGCTCAAGCAAAAAAACGTGAGCTACT
TGCACTTACCATTGGCAACCGATGGCTTGGGGAATAAACTGTCAAAACAAAATCATGCCACCGCGATAGAGCTCGACAAC
CCAAAACCGACGTTAATCAATGCGATGCGATTCTTAGGTTTTGATATCCCGAATGCTCTTTTCGAAGCGTCAATGGATGA
AGTTTTATTGTGGGGCTGCCAGCAATGGAACGTCACTCAGTTACCTGATAGTTTACAAAAAGAGCACAGTAATGAGTTCG
AAACTAACGGCAAATCGCAATAA

Upstream 100 bases:

>100_bases
TTCTAAAAAGCGGTTTATATCGTTGTTGATAGCGATAAACTAATCGCCAAACGTCTTAAGAATCGGCTACTGCGGTACCA
TCAAGATTAGGTTTTCACTT

Downstream 100 bases:

>100_bases
CGATACATAAAAATACCCTAACAAATACCTGCGACTAAGCAGACGATGTTCTCAAATGGCTCGCGCTAAGCTATTATTAG
CCGCAATTAAACTCTGCACT

Product: glutamyl-Q tRNA(Asp) synthetase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNYIGRFAPSPSGPLHFGSLVAALGSYFQAKSNQGQWLVRMEDLDPPREMAGAADLILKTLEAYHLYWDGEVVYQSQRHD
LYQAQIDQWVTDNQAYYCQCTRKQIKSLGGFYSGRCRDKGLVDSGEQAVRLCMDFPIESFDDVRHGTIQIPKALAEEDFI
IKRRDGLFAYNLAVVLDDIEQGVTEVVRGADLIEPTGRQISLYKTLKQKNVSYLHLPLATDGLGNKLSKQNHATAIELDN
PKPTLINAMRFLGFDIPNALFEASMDEVLLWGCQQWNVTQLPDSLQKEHSNEFETNGKSQ

Sequences:

>Translated_300_residues
MNYIGRFAPSPSGPLHFGSLVAALGSYFQAKSNQGQWLVRMEDLDPPREMAGAADLILKTLEAYHLYWDGEVVYQSQRHD
LYQAQIDQWVTDNQAYYCQCTRKQIKSLGGFYSGRCRDKGLVDSGEQAVRLCMDFPIESFDDVRHGTIQIPKALAEEDFI
IKRRDGLFAYNLAVVLDDIEQGVTEVVRGADLIEPTGRQISLYKTLKQKNVSYLHLPLATDGLGNKLSKQNHATAIELDN
PKPTLINAMRFLGFDIPNALFEASMDEVLLWGCQQWNVTQLPDSLQKEHSNEFETNGKSQ
>Mature_300_residues
MNYIGRFAPSPSGPLHFGSLVAALGSYFQAKSNQGQWLVRMEDLDPPREMAGAADLILKTLEAYHLYWDGEVVYQSQRHD
LYQAQIDQWVTDNQAYYCQCTRKQIKSLGGFYSGRCRDKGLVDSGEQAVRLCMDFPIESFDDVRHGTIQIPKALAEEDFI
IKRRDGLFAYNLAVVLDDIEQGVTEVVRGADLIEPTGRQISLYKTLKQKNVSYLHLPLATDGLGNKLSKQNHATAIELDN
PKPTLINAMRFLGFDIPNALFEASMDEVLLWGCQQWNVTQLPDSLQKEHSNEFETNGKSQ

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=300, Percent_Identity=29.6666666666667, Blast_Score=118, Evalue=5e-27,
Organism=Escherichia coli, GI226510925, Length=285, Percent_Identity=54.3859649122807, Blast_Score=308, Evalue=3e-85,
Organism=Escherichia coli, GI1788743, Length=248, Percent_Identity=34.2741935483871, Blast_Score=137, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71993394, Length=250, Percent_Identity=30, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324540, Length=254, Percent_Identity=30.3149606299213, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24665321, Length=261, Percent_Identity=28.735632183908, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 33868; Mature: 33868

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYIGRFAPSPSGPLHFGSLVAALGSYFQAKSNQGQWLVRMEDLDPPREMAGAADLILKT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
LEAYHLYWDGEVVYQSQRHDLYQAQIDQWVTDNQAYYCQCTRKQIKSLGGFYSGRCRDKG
HHHHEEEECCEEEEECHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCCCCCC
LVDSGEQAVRLCMDFPIESFDDVRHGTIQIPKALAEEDFIIKRRDGLFAYNLAVVLDDIE
CCCCCHHHHHHHHHCCCCHHHHCCCCEEECCHHHCCCCCEEEECCCCEEEHHHHHHHHHH
QGVTEVVRGADLIEPTGRQISLYKTLKQKNVSYLHLPLATDGLGNKLSKQNHATAIELDN
HHHHHHHHCCCCCCCCCCEEHHHHHHHHCCCCEEEEEECCCCCCCHHCCCCCCEEEEECC
PKPTLINAMRFLGFDIPNALFEASMDEVLLWGCQQWNVTQLPDSLQKEHSNEFETNGKSQ
CCHHHHHHHHHHCCCCCHHHHHHCHHHHHHHCCCCCCHHHCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNYIGRFAPSPSGPLHFGSLVAALGSYFQAKSNQGQWLVRMEDLDPPREMAGAADLILKT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
LEAYHLYWDGEVVYQSQRHDLYQAQIDQWVTDNQAYYCQCTRKQIKSLGGFYSGRCRDKG
HHHHEEEECCEEEEECHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCCCCCC
LVDSGEQAVRLCMDFPIESFDDVRHGTIQIPKALAEEDFIIKRRDGLFAYNLAVVLDDIE
CCCCCHHHHHHHHHCCCCHHHHCCCCEEECCHHHCCCCCEEEECCCCEEEHHHHHHHHHH
QGVTEVVRGADLIEPTGRQISLYKTLKQKNVSYLHLPLATDGLGNKLSKQNHATAIELDN
HHHHHHHHCCCCCCCCCCEEHHHHHHHHCCCCEEEEEECCCCCCCHHCCCCCCEEEEECC
PKPTLINAMRFLGFDIPNALFEASMDEVLLWGCQQWNVTQLPDSLQKEHSNEFETNGKSQ
CCHHHHHHHHHHCCCCCHHHHHHCHHHHHHHCCCCCCHHHCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA