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The map label for this gene is yciR [C]

Identifier: 218710435

GI number: 218710435

Start: 2641817

End: 2643856

Strand: Direct

Name: yciR [C]

Synonym: VS_2472

Alternate gene names: 218710435

Gene position: 2641817-2643856 (Clockwise)

Preceding gene: 218710422

Following gene: 218710436

Centisome position: 80.07

GC content: 44.17

Gene sequence:

>2040_bases
ATGCCTCCCCAGCAACTACAACATTGGTTTACACAGCTTACTGCAAACAGCCCGTTCTTTTTTGCGGTACTTGATGCTCA
ACATAACTATTTTATGGTGAATGAGCGTTACTGTGATATTGCTGGTTTAAGTAAAACAGAGCTTGTAGGCATGAATGACC
GCCAAACCTTGGGCGAGCAATTCTACCAACACCTTAAGCCTTACTATGAGCGTGCATTCAATGGCGAAACAATTGAGGCG
GAAATCACCCTAAACGAAACGGCTTTAGACACTAGCCTTCATTTCAGCCTATCTCCGCTTACCAATGGTAAAAAGACTGA
ATACATCATCTTTCACGCCTTCGATACATCTGAAAACCAAGTACTTGTCCGTTCTTTAGAAGAGTCTGAAGCGAAATTCC
ACAAGCTATCTCACCTGCTCCCAGACGGATTGCTATTAGTTGAAAACGACTACATTCTGTCTTCGAACCCTGCAGCTGCA
CGCTTACTTGGTTTTAACTCCACCACAGAATTGATTGGCGAAGAGTTAGGCCGATTATTTATCGATGAACAAACCAAAAC
AGTCTTTAATAATGACCTCAGCTCCATTATTTCTGAGTCTGGCTTGGTTTGTTTAACGGGTGCTCGATGTGGCTTTGAAC
GTAAAGTTCAGTTAAATATCGACTCGACGGTCATTCTTGGAAGCAGTACCCAACTCGTACTTATTCAAGACGCTCAAGAA
ACAACAAAACAATACACACCCGCTAACAGTGAAGATGCCTACATCGATACACTGACTAAGCTCTACAACCGACTTGGGTT
TACCAAAAGCCTTGAGCAGTTCATTCACAACAAGACCCCTGTTGTGATGCTCTACTTAGACATCGATAACTTCAAAAATA
TCAATGACTCACTTGGCCACCACATCGGTGATAAAGTGATTAAAGAGGTCGCATCTCGCTTAAAACGACAACTGCCTCGT
CAAGCTATTATTGGCCATTTAGGCGGTGATGAATTTGGTATTATTCTGCCTGAGCCTGAACACCCACGAACACCTGAAAT
ACTCTCTGAAAAGATCATATCTCTGATCAACCAACCCTTCGATCTCCACCATTTTAGCAAGCGTTTAGCCTGCTCGATTG
GTAGTGTGAGCTTTCCTCACGATGGCAGTGACGCACGTATCTTGCTACAGAATGCTGACACCGCAATGTATGAAGCTAAG
GATCGTGGACGCAACCGCCTGATCAAGTTCAACGAACAGATGAACAAAGAAGCGCGAATGCGACTGTGGCTTGAGATAGA
ACTGCAAAAAGCACTGCAACAGAACGGGCTTGAGGTTTGGTACCAACCAAAAGTAAATGCGCGTGACTTCACCATTAACG
GAGCAGAAGCTCTGGTACGTTGGAAACACCCCGTAGAAGGTTATATTAGCCCTGCCGCATTTATTCCTGTAGCGGAACGA
GCTGGCCTTATTGAACAACTTGGTCGTGTGGTAATGCGCGAAGTATTTGCCACGGTGAAACGTTGGAAGATGCAAGGTAT
TTTACCTGGTCGCGTCGCGATCAACCTTTCACCAGAGCAGTTTGGTAATCCAAAATTGATTGATTTCATGGAGAAGTTGC
TGCGTTCTACTGAGCTAGATCCAAGTGCGATTACCTTTGAGCTTACAGAAAGTGCCGTAATGAGTGATAGTGAGCACACG
CTTCAAATGCTGAACGCGATTAAGAGACTTGGCTTTGCGTTATCCATCGATGACTTTGGTACGGGTTACTCTTCTCTATC
TTACCTTGCTCGCTTTCCGATTGATGAGCTTAAAATTGACCGAGCTTTTATCTCAGATATCGATACCTTACCAAAGCAAA
TTACCGTAATTGAAAACATCATCAACCTTGGGAAATCTCTCGATTTAACCGTGGTTGCAGAGGGTGTCGAAACCAGTGAA
CAAGCAACCCTGCTGTCTAACCTCAACTGTGGTTCAATTCAAGGTTTCCACTTCTATCGCCCTCAACCAAAACAAGAGGT
TGAAGAACTGTTCGCCCAAAACCGTCGTCACAAGAATTAA

Upstream 100 bases:

>100_bases
AATCGCTGCACTCACAAGTAAACATCGATAGCTGAACAAAAAGTAATCAATGCTTATCGATAGTGAATATTCAAGCTCTT
GGAGAATTGGTAGTACTTTG

Downstream 100 bases:

>100_bases
TTAAACACGCCCTCCAACACCAAGCTAAAGCGTAAATTCGCCATTCGTCAGTACCTCAAATGGGGTAAAAGCAGATTTAT
CCATCTAAACCTGCCTTACA

Product: c-di-GMP phosphodiesterase A-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MPPQQLQHWFTQLTANSPFFFAVLDAQHNYFMVNERYCDIAGLSKTELVGMNDRQTLGEQFYQHLKPYYERAFNGETIEA
EITLNETALDTSLHFSLSPLTNGKKTEYIIFHAFDTSENQVLVRSLEESEAKFHKLSHLLPDGLLLVENDYILSSNPAAA
RLLGFNSTTELIGEELGRLFIDEQTKTVFNNDLSSIISESGLVCLTGARCGFERKVQLNIDSTVILGSSTQLVLIQDAQE
TTKQYTPANSEDAYIDTLTKLYNRLGFTKSLEQFIHNKTPVVMLYLDIDNFKNINDSLGHHIGDKVIKEVASRLKRQLPR
QAIIGHLGGDEFGIILPEPEHPRTPEILSEKIISLINQPFDLHHFSKRLACSIGSVSFPHDGSDARILLQNADTAMYEAK
DRGRNRLIKFNEQMNKEARMRLWLEIELQKALQQNGLEVWYQPKVNARDFTINGAEALVRWKHPVEGYISPAAFIPVAER
AGLIEQLGRVVMREVFATVKRWKMQGILPGRVAINLSPEQFGNPKLIDFMEKLLRSTELDPSAITFELTESAVMSDSEHT
LQMLNAIKRLGFALSIDDFGTGYSSLSYLARFPIDELKIDRAFISDIDTLPKQITVIENIINLGKSLDLTVVAEGVETSE
QATLLSNLNCGSIQGFHFYRPQPKQEVEELFAQNRRHKN

Sequences:

>Translated_679_residues
MPPQQLQHWFTQLTANSPFFFAVLDAQHNYFMVNERYCDIAGLSKTELVGMNDRQTLGEQFYQHLKPYYERAFNGETIEA
EITLNETALDTSLHFSLSPLTNGKKTEYIIFHAFDTSENQVLVRSLEESEAKFHKLSHLLPDGLLLVENDYILSSNPAAA
RLLGFNSTTELIGEELGRLFIDEQTKTVFNNDLSSIISESGLVCLTGARCGFERKVQLNIDSTVILGSSTQLVLIQDAQE
TTKQYTPANSEDAYIDTLTKLYNRLGFTKSLEQFIHNKTPVVMLYLDIDNFKNINDSLGHHIGDKVIKEVASRLKRQLPR
QAIIGHLGGDEFGIILPEPEHPRTPEILSEKIISLINQPFDLHHFSKRLACSIGSVSFPHDGSDARILLQNADTAMYEAK
DRGRNRLIKFNEQMNKEARMRLWLEIELQKALQQNGLEVWYQPKVNARDFTINGAEALVRWKHPVEGYISPAAFIPVAER
AGLIEQLGRVVMREVFATVKRWKMQGILPGRVAINLSPEQFGNPKLIDFMEKLLRSTELDPSAITFELTESAVMSDSEHT
LQMLNAIKRLGFALSIDDFGTGYSSLSYLARFPIDELKIDRAFISDIDTLPKQITVIENIINLGKSLDLTVVAEGVETSE
QATLLSNLNCGSIQGFHFYRPQPKQEVEELFAQNRRHKN
>Mature_678_residues
PPQQLQHWFTQLTANSPFFFAVLDAQHNYFMVNERYCDIAGLSKTELVGMNDRQTLGEQFYQHLKPYYERAFNGETIEAE
ITLNETALDTSLHFSLSPLTNGKKTEYIIFHAFDTSENQVLVRSLEESEAKFHKLSHLLPDGLLLVENDYILSSNPAAAR
LLGFNSTTELIGEELGRLFIDEQTKTVFNNDLSSIISESGLVCLTGARCGFERKVQLNIDSTVILGSSTQLVLIQDAQET
TKQYTPANSEDAYIDTLTKLYNRLGFTKSLEQFIHNKTPVVMLYLDIDNFKNINDSLGHHIGDKVIKEVASRLKRQLPRQ
AIIGHLGGDEFGIILPEPEHPRTPEILSEKIISLINQPFDLHHFSKRLACSIGSVSFPHDGSDARILLQNADTAMYEAKD
RGRNRLIKFNEQMNKEARMRLWLEIELQKALQQNGLEVWYQPKVNARDFTINGAEALVRWKHPVEGYISPAAFIPVAERA
GLIEQLGRVVMREVFATVKRWKMQGILPGRVAINLSPEQFGNPKLIDFMEKLLRSTELDPSAITFELTESAVMSDSEHTL
QMLNAIKRLGFALSIDDFGTGYSSLSYLARFPIDELKIDRAFISDIDTLPKQITVIENIINLGKSLDLTVVAEGVETSEQ
ATLLSNLNCGSIQGFHFYRPQPKQEVEELFAQNRRHKN

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=423, Percent_Identity=35.4609929078014, Blast_Score=279, Evalue=5e-76,
Organism=Escherichia coli, GI87081921, Length=412, Percent_Identity=32.0388349514563, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI226510982, Length=444, Percent_Identity=27.9279279279279, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI87081845, Length=234, Percent_Identity=36.3247863247863, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1788502, Length=241, Percent_Identity=36.9294605809129, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1790496, Length=239, Percent_Identity=35.5648535564854, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=34.5833333333333, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1787055, Length=362, Percent_Identity=25.6906077348066, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081980, Length=252, Percent_Identity=34.9206349206349, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1786507, Length=237, Percent_Identity=32.0675105485232, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI87082096, Length=456, Percent_Identity=23.6842105263158, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788849, Length=262, Percent_Identity=30.9160305343511, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788381, Length=274, Percent_Identity=28.1021897810219, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=31.055900621118, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787802, Length=157, Percent_Identity=33.1210191082803, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788956, Length=159, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082007, Length=162, Percent_Identity=34.5679012345679, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=33.75, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787410, Length=152, Percent_Identity=30.2631578947368, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787056, Length=238, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788085, Length=167, Percent_Identity=29.3413173652695, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786584, Length=161, Percent_Identity=32.9192546583851, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789650, Length=437, Percent_Identity=19.2219679633867, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=31.0975609756098, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87081977, Length=166, Percent_Identity=31.3253012048193, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081881, Length=205, Percent_Identity=29.7560975609756, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081974, Length=149, Percent_Identity=32.2147651006711, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 76867; Mature: 76735

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50883 EAL ; PS50887 GGDEF ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPQQLQHWFTQLTANSPFFFAVLDAQHNYFMVNERYCDIAGLSKTELVGMNDRQTLGEQ
CCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCEECCCCCCCCEEECCCCHHHHHHH
FYQHLKPYYERAFNGETIEAEITLNETALDTSLHFSLSPLTNGKKTEYIIFHAFDTSENQ
HHHHHHHHHHHCCCCCEEEEEEEECCCEECCEEEEEECCCCCCCCEEEEEEEEECCCCCH
VLVRSLEESEAKFHKLSHLLPDGLLLVENDYILSSNPAAARLLGFNSTTELIGEELGRLF
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECCCCCCEEEECCCCHHHHHHHHHHHHE
IDEQTKTVFNNDLSSIISESGLVCLTGARCGFERKVQLNIDSTVILGSSTQLVLIQDAQE
ECCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCEEEECCCCEEEEEECCHH
TTKQYTPANSEDAYIDTLTKLYNRLGFTKSLEQFIHNKTPVVMLYLDIDNFKNINDSLGH
HHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHH
HIGDKVIKEVASRLKRQLPRQAIIGHLGGDEFGIILPEPEHPRTPEILSEKIISLINQPF
HHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
DLHHFSKRLACSIGSVSFPHDGSDARILLQNADTAMYEAKDRGRNRLIKFNEQMNKEARM
CHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCEEEEHHHCCCHHHE
RLWLEIELQKALQQNGLEVWYQPKVNARDFTINGAEALVRWKHPVEGYISPAAFIPVAER
EEEEEEHHHHHHHHCCCEEEEECCCCCCEEEECCHHHHEEECCCCCCCCCCHHHCCHHHH
AGLIEQLGRVVMREVFATVKRWKMQGILPGRVAINLSPEQFGNPKLIDFMEKLLRSTELD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCCCHHHHHHHHHHHHCCCC
PSAITFELTESAVMSDSEHTLQMLNAIKRLGFALSIDDFGTGYSSLSYLARFPIDELKID
CCEEEEEECHHHHHCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCHHHHHHH
RAFISDIDTLPKQITVIENIINLGKSLDLTVVAEGVETSEQATLLSNLNCGSIQGFHFYR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCEECCC
PQPKQEVEELFAQNRRHKN
CCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PPQQLQHWFTQLTANSPFFFAVLDAQHNYFMVNERYCDIAGLSKTELVGMNDRQTLGEQ
CHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCEECCCCCCCCEEECCCCHHHHHHH
FYQHLKPYYERAFNGETIEAEITLNETALDTSLHFSLSPLTNGKKTEYIIFHAFDTSENQ
HHHHHHHHHHHCCCCCEEEEEEEECCCEECCEEEEEECCCCCCCCEEEEEEEEECCCCCH
VLVRSLEESEAKFHKLSHLLPDGLLLVENDYILSSNPAAARLLGFNSTTELIGEELGRLF
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECCCCCCEEEECCCCHHHHHHHHHHHHE
IDEQTKTVFNNDLSSIISESGLVCLTGARCGFERKVQLNIDSTVILGSSTQLVLIQDAQE
ECCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCEEEECCCCEEEEEECCHH
TTKQYTPANSEDAYIDTLTKLYNRLGFTKSLEQFIHNKTPVVMLYLDIDNFKNINDSLGH
HHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHH
HIGDKVIKEVASRLKRQLPRQAIIGHLGGDEFGIILPEPEHPRTPEILSEKIISLINQPF
HHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
DLHHFSKRLACSIGSVSFPHDGSDARILLQNADTAMYEAKDRGRNRLIKFNEQMNKEARM
CHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCEEEEHHHCCCHHHE
RLWLEIELQKALQQNGLEVWYQPKVNARDFTINGAEALVRWKHPVEGYISPAAFIPVAER
EEEEEEHHHHHHHHCCCEEEEECCCCCCEEEECCHHHHEEECCCCCCCCCCHHHCCHHHH
AGLIEQLGRVVMREVFATVKRWKMQGILPGRVAINLSPEQFGNPKLIDFMEKLLRSTELD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCCCHHHHHHHHHHHHCCCC
PSAITFELTESAVMSDSEHTLQMLNAIKRLGFALSIDDFGTGYSSLSYLARFPIDELKID
CCEEEEEECHHHHHCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCHHHHHHH
RAFISDIDTLPKQITVIENIINLGKSLDLTVVAEGVETSEQATLLSNLNCGSIQGFHFYR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCEECCC
PQPKQEVEELFAQNRRHKN
CCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]