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The map label for this gene is yeiJ [C]

Identifier: 218710427

GI number: 218710427

Start: 2635276

End: 2636538

Strand: Reverse

Name: yeiJ [C]

Synonym: VS_2464

Alternate gene names: 218710427

Gene position: 2636538-2635276 (Counterclockwise)

Preceding gene: 218710428

Following gene: 218710426

Centisome position: 79.91

GC content: 45.92

Gene sequence:

>1263_bases
ATGAGCCTGTTTATGAGCCTCGTCGGAATGGTTGCACTGATTGCAATCGCAGTACTACTATCCGACAACCGCAAAGCAAT
TAATCTAAGAACAGTGGGTGGCGCTTTCGCTATTCAATTCGCACTTGGTGCATTCGTACTTTACATCCCTTGGGGTCGTG
ATCTACTTGCAGGTTTCTCTGCTGGTGTAGCAAACGTGATCGACTACGGTAAAGATGGTACTGGCTTCCTATTTGGTAGC
CTTGTTAACTTCTCAGTTGACGGTATCGGATTCATCTTTGCATTCCAAGTTCTACCAACACTAATCTTCTTCTCTGCTCT
TATCTCTGTACTTTACTACATTGGTGCGATGCAAGTTGTAATCAAGGTTCTTGGTGGTGGTCTTCAGAAAGCTCTAGGTA
CTTCTCGCGCCGAGTCTATGTCTGCAGCTGCAAACATCTTCGTTGGTCAAACGGAAGCGCCTCTAGTTGTTCGTCCTTTT
GTTCCTAAAATGACTAACTCTGAACTATTCGCAGTAATGTGTGGTGGTTTAGCGTCTGTTGCTGGTGGTGTACTAGCGGG
TTACGCATCTATGGGTGTACCTCTAGAGTACCTAGTAGCAGCGTCATTCATGGCAGCACCTGGTGGTCTACTATTCGCTA
AAATCATCAAGCCTGAAACTGATGAAGTTGACGAGAACCTAGGTTCAGACATCGACGGTGGCGACGACAAGCCTGCTAAC
GTTATCGATGCAGCTGCTGGCGGTGCGTCAGTTGGTCTACAACTAGCACTTAACGTTGGTGCAATGCTACTAGCATTCAT
CGGTCTAATCGCTCTTATCAACGGTATCCTAGGTGGCATCGGTGGTTGGTTCGGTATGGAAAACCTAACTCTAGAACTTC
TTCTAGGTTGGATCTTCGCACCGTTAGCATTCATCATTGGTGTTCCATGGGAAGAAGCAACTATTGCTGGTTCTTTCATT
GGTCAGAAGACAGTTGTTAACGAGTTCGTTGCATACCTAAACTTCGTACCATACATCGGTGAAAACGCTCAAATCGTTGA
AGCGACTGGTCAAGTAATGTCTGTTAAGACTCAAGCAATTATCTCGTTCGCTCTATGTGGTTTCGCAAACCTTTCTTCAA
TTGCGATTCTTCTAGGTGGTCTAGGTGGTATTGCTCCAAACCGTCGTCACGACATCGCACGTATGGGTGTTAAAGCGGTT
GTAGCTGGTACTCTATCTAACCTGATGGCAGCAACAATTGCTGGCTTCTTCCTGTCTTTCTAA

Upstream 100 bases:

>100_bases
CGGCATTACTTTATTAGTGGTCGCATGAGTATAATTGCCTCCGCTTTATAGCCCCATTTTGTAACACGCCAATAAATAAC
TAATAAGGAAGTCATAAACT

Downstream 100 bases:

>100_bases
TCAGTTAGAAATCGATATATAGACGCCATAATAATATCGCCCCGTAGCAAGAAATTGCTGCGGGGCTTTTTTGTTTTTGG
GCCTAGTGATTTTGAGCATT

Product: NupC family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSLFMSLVGMVALIAIAVLLSDNRKAINLRTVGGAFAIQFALGAFVLYIPWGRDLLAGFSAGVANVIDYGKDGTGFLFGS
LVNFSVDGIGFIFAFQVLPTLIFFSALISVLYYIGAMQVVIKVLGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPF
VPKMTNSELFAVMCGGLASVAGGVLAGYASMGVPLEYLVAASFMAAPGGLLFAKIIKPETDEVDENLGSDIDGGDDKPAN
VIDAAAGGASVGLQLALNVGAMLLAFIGLIALINGILGGIGGWFGMENLTLELLLGWIFAPLAFIIGVPWEEATIAGSFI
GQKTVVNEFVAYLNFVPYIGENAQIVEATGQVMSVKTQAIISFALCGFANLSSIAILLGGLGGIAPNRRHDIARMGVKAV
VAGTLSNLMAATIAGFFLSF

Sequences:

>Translated_420_residues
MSLFMSLVGMVALIAIAVLLSDNRKAINLRTVGGAFAIQFALGAFVLYIPWGRDLLAGFSAGVANVIDYGKDGTGFLFGS
LVNFSVDGIGFIFAFQVLPTLIFFSALISVLYYIGAMQVVIKVLGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPF
VPKMTNSELFAVMCGGLASVAGGVLAGYASMGVPLEYLVAASFMAAPGGLLFAKIIKPETDEVDENLGSDIDGGDDKPAN
VIDAAAGGASVGLQLALNVGAMLLAFIGLIALINGILGGIGGWFGMENLTLELLLGWIFAPLAFIIGVPWEEATIAGSFI
GQKTVVNEFVAYLNFVPYIGENAQIVEATGQVMSVKTQAIISFALCGFANLSSIAILLGGLGGIAPNRRHDIARMGVKAV
VAGTLSNLMAATIAGFFLSF
>Mature_419_residues
SLFMSLVGMVALIAIAVLLSDNRKAINLRTVGGAFAIQFALGAFVLYIPWGRDLLAGFSAGVANVIDYGKDGTGFLFGSL
VNFSVDGIGFIFAFQVLPTLIFFSALISVLYYIGAMQVVIKVLGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFV
PKMTNSELFAVMCGGLASVAGGVLAGYASMGVPLEYLVAASFMAAPGGLLFAKIIKPETDEVDENLGSDIDGGDDKPANV
IDAAAGGASVGLQLALNVGAMLLAFIGLIALINGILGGIGGWFGMENLTLELLLGWIFAPLAFIIGVPWEEATIAGSFIG
QKTVVNEFVAYLNFVPYIGENAQIVEATGQVMSVKTQAIISFALCGFANLSSIAILLGGLGGIAPNRRHDIARMGVKAVV
AGTLSNLMAATIAGFFLSF

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI42542381, Length=417, Percent_Identity=36.21103117506, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI11545853, Length=357, Percent_Identity=39.4957983193277, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI227116277, Length=411, Percent_Identity=36.0097323600973, Blast_Score=268, Evalue=8e-72,
Organism=Escherichia coli, GI1788485, Length=422, Percent_Identity=49.0521327014218, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788488, Length=422, Percent_Identity=50.9478672985782, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1788737, Length=421, Percent_Identity=30.166270783848, Blast_Score=179, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17560276, Length=405, Percent_Identity=32.3456790123457, Blast_Score=207, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI71991794, Length=404, Percent_Identity=31.9306930693069, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI25146537, Length=228, Percent_Identity=31.140350877193, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45552519, Length=412, Percent_Identity=38.5922330097087, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI45552517, Length=412, Percent_Identity=38.5922330097087, Blast_Score=268, Evalue=3e-72,
Organism=Drosophila melanogaster, GI19921868, Length=412, Percent_Identity=38.5922330097087, Blast_Score=268, Evalue=3e-72,
Organism=Drosophila melanogaster, GI281360430, Length=409, Percent_Identity=35.2078239608802, Blast_Score=239, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43418; Mature: 43286

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFMSLVGMVALIAIAVLLSDNRKAINLRTVGGAFAIQFALGAFVLYIPWGRDLLAGFS
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHEEEECCCHHHHHHHH
AGVANVIDYGKDGTGFLFGSLVNFSVDGIGFIFAFQVLPTLIFFSALISVLYYIGAMQVV
HHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVLGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTNSELFAVMCGGLASV
HHHHCCHHHHHHCCHHHHHHHHHHHEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
AGGVLAGYASMGVPLEYLVAASFMAAPGGLLFAKIIKPETDEVDENLGSDIDGGDDKPAN
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCH
VIDAAAGGASVGLQLALNVGAMLLAFIGLIALINGILGGIGGWFGMENLTLELLLGWIFA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
PLAFIIGVPWEEATIAGSFIGQKTVVNEFVAYLNFVPYIGENAQIVEATGQVMSVKTQAI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHH
ISFALCGFANLSSIAILLGGLGGIAPNRRHDIARMGVKAVVAGTLSNLMAATIAGFFLSF
HHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLFMSLVGMVALIAIAVLLSDNRKAINLRTVGGAFAIQFALGAFVLYIPWGRDLLAGFS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHEEEECCCHHHHHHHH
AGVANVIDYGKDGTGFLFGSLVNFSVDGIGFIFAFQVLPTLIFFSALISVLYYIGAMQVV
HHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVLGGGLQKALGTSRAESMSAAANIFVGQTEAPLVVRPFVPKMTNSELFAVMCGGLASV
HHHHCCHHHHHHCCHHHHHHHHHHHEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
AGGVLAGYASMGVPLEYLVAASFMAAPGGLLFAKIIKPETDEVDENLGSDIDGGDDKPAN
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCH
VIDAAAGGASVGLQLALNVGAMLLAFIGLIALINGILGGIGGWFGMENLTLELLLGWIFA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
PLAFIIGVPWEEATIAGSFIGQKTVVNEFVAYLNFVPYIGENAQIVEATGQVMSVKTQAI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHH
ISFALCGFANLSSIAILLGGLGGIAPNRRHDIARMGVKAVVAGTLSNLMAATIAGFFLSF
HHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]