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The map label for this gene is yjjV [H]

Identifier: 218710428

GI number: 218710428

Start: 2636743

End: 2637591

Strand: Reverse

Name: yjjV [H]

Synonym: VS_2465

Alternate gene names: 218710428

Gene position: 2637591-2636743 (Counterclockwise)

Preceding gene: 218710429

Following gene: 218710427

Centisome position: 79.94

GC content: 41.81

Gene sequence:

>849_bases
GTGATCCTCAAGGACAACAAACAGAGAGTAGGGAAGATGACACCAGAATTAAGTGAATTTCCGCTGTTTGACACTCATTG
CCATGCGGACTTTGACATCTTTGAGCAAGGTTTTTCACTTGATAAAGGTATTGAAGGTTACGTTAAAGAAGCGAAACAGG
CGCAAGTCGAGAAGTTAATCATCCCTTCTATTGGCCAAAGTAACTGGAGGAAGCTTGGTGAGATCGCTCAATCTTACCCT
AATGTTTACTACGCTTTAGGTTTCCATCCTTATTTTTTAGAGCAAGCCAATGACGAGCAATTCTCAGAGCTTCGCCGATT
ACTCTCATCAAAAACCAGTCAATGTGTTGCGATAGGAGAGTGTGGTCTCGACTTTTTTGTCGATGTTGCACGGGAGAAAC
AAGAGCGTTTTTTCATTCAACAAATAGAGCTAGCTAAGGCGTTTAAGCTGCCTTTAATCATCCATGAAAGGAAGTCTTTT
AACCGACTTATTGAGCTAATAAAGCAGTATAAATTTACTTTGGGTGGCGTGATTCATGGATTTTCAGGGAGCGAACAGCA
GGCTTTGGCGTGGATTCAGCTTGGTTTCTATATTGGTGTCGGTGGAACGATTACTTACCCAAGAGCACAAAAAACACGCA
CCACTATCTCAAAACTGCCTCTTGAGTGCCTGGTATTAGAAACGGATGCCCCGGATATGCCCATGCATGGAAAACAAGGA
AATGTTAATCATTCCAAGTATTTAGTTACGCTCTTGAATGAACTATTTTTGCTTAGAAAAGAACCGAAGCAATCGGTTGC
AGCGCAAATTTGGCAAAATAGCCATCGCGCATTCGGTATATGTGAATAA

Upstream 100 bases:

>100_bases
ATGTTCAGTTGGATAAAAGCTTGGATTAATAAATACGATAAGTGGTGCGAAGAGCTTGGCTTAACGCCTGAAAATAAGCG
CAGCTGCGTGGCTTATCGCC

Downstream 100 bases:

>100_bases
AATCGAAGGTTTTTGTTTATCGTTTGCGTAAATTGCACTTGGCTTGTGATTCGGCTCACATTTACGTGTGAATGGTACAT
GAATCTTCTACGAAAGTGTG

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MILKDNKQRVGKMTPELSEFPLFDTHCHADFDIFEQGFSLDKGIEGYVKEAKQAQVEKLIIPSIGQSNWRKLGEIAQSYP
NVYYALGFHPYFLEQANDEQFSELRRLLSSKTSQCVAIGECGLDFFVDVAREKQERFFIQQIELAKAFKLPLIIHERKSF
NRLIELIKQYKFTLGGVIHGFSGSEQQALAWIQLGFYIGVGGTITYPRAQKTRTTISKLPLECLVLETDAPDMPMHGKQG
NVNHSKYLVTLLNELFLLRKEPKQSVAAQIWQNSHRAFGICE

Sequences:

>Translated_282_residues
MILKDNKQRVGKMTPELSEFPLFDTHCHADFDIFEQGFSLDKGIEGYVKEAKQAQVEKLIIPSIGQSNWRKLGEIAQSYP
NVYYALGFHPYFLEQANDEQFSELRRLLSSKTSQCVAIGECGLDFFVDVAREKQERFFIQQIELAKAFKLPLIIHERKSF
NRLIELIKQYKFTLGGVIHGFSGSEQQALAWIQLGFYIGVGGTITYPRAQKTRTTISKLPLECLVLETDAPDMPMHGKQG
NVNHSKYLVTLLNELFLLRKEPKQSVAAQIWQNSHRAFGICE
>Mature_282_residues
MILKDNKQRVGKMTPELSEFPLFDTHCHADFDIFEQGFSLDKGIEGYVKEAKQAQVEKLIIPSIGQSNWRKLGEIAQSYP
NVYYALGFHPYFLEQANDEQFSELRRLLSSKTSQCVAIGECGLDFFVDVAREKQERFFIQQIELAKAFKLPLIIHERKSF
NRLIELIKQYKFTLGGVIHGFSGSEQQALAWIQLGFYIGVGGTITYPRAQKTRTTISKLPLECLVLETDAPDMPMHGKQG
NVNHSKYLVTLLNELFLLRKEPKQSVAAQIWQNSHRAFGICE

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=195, Percent_Identity=29.7435897435897, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI225903439, Length=164, Percent_Identity=32.9268292682927, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI110349730, Length=245, Percent_Identity=26.1224489795918, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI110349734, Length=245, Percent_Identity=26.530612244898, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226061853, Length=250, Percent_Identity=25.6, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=26.6375545851528, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI225903424, Length=207, Percent_Identity=26.5700483091787, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI226061614, Length=239, Percent_Identity=24.6861924686192, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=42.4710424710425, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1787342, Length=261, Percent_Identity=26.8199233716475, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI48994985, Length=264, Percent_Identity=28.7878787878788, Blast_Score=94, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17559024, Length=201, Percent_Identity=30.8457711442786, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71980746, Length=222, Percent_Identity=26.1261261261261, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=253, Percent_Identity=26.8774703557312, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648690, Length=242, Percent_Identity=28.099173553719, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI221330018, Length=263, Percent_Identity=25.0950570342205, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24586117, Length=263, Percent_Identity=25.0950570342205, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 32238; Mature: 32238

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKDNKQRVGKMTPELSEFPLFDTHCHADFDIFEQGFSLDKGIEGYVKEAKQAQVEKLI
CCCCCCHHHHHCCCCCHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IPSIGQSNWRKLGEIAQSYPNVYYALGFHPYFLEQANDEQFSELRRLLSSKTSQCVAIGE
CCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEC
CGLDFFVDVAREKQERFFIQQIELAKAFKLPLIIHERKSFNRLIELIKQYKFTLGGVIHG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHEEEC
FSGSEQQALAWIQLGFYIGVGGTITYPRAQKTRTTISKLPLECLVLETDAPDMPMHGKQG
CCCCHHHHHHHHEEHEEEECCCEEECCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCC
NVNHSKYLVTLLNELFLLRKEPKQSVAAQIWQNSHRAFGICE
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MILKDNKQRVGKMTPELSEFPLFDTHCHADFDIFEQGFSLDKGIEGYVKEAKQAQVEKLI
CCCCCCHHHHHCCCCCHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IPSIGQSNWRKLGEIAQSYPNVYYALGFHPYFLEQANDEQFSELRRLLSSKTSQCVAIGE
CCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEC
CGLDFFVDVAREKQERFFIQQIELAKAFKLPLIIHERKSFNRLIELIKQYKFTLGGVIHG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHEEEC
FSGSEQQALAWIQLGFYIGVGGTITYPRAQKTRTTISKLPLECLVLETDAPDMPMHGKQG
CCCCHHHHHHHHEEHEEEECCCEEECCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCC
NVNHSKYLVTLLNELFLLRKEPKQSVAAQIWQNSHRAFGICE
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]