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The map label for this gene is gpwA [H]

Identifier: 218710125

GI number: 218710125

Start: 2303166

End: 2303711

Strand: Direct

Name: gpwA [H]

Synonym: VS_2146

Alternate gene names: 218710125

Gene position: 2303166-2303711 (Clockwise)

Preceding gene: 218710124

Following gene: 218710126

Centisome position: 69.81

GC content: 45.6

Gene sequence:

>546_bases
ATGAAACATTCACTGCTGTGCTCCACCGCCCTAATCGCGAGCCTAACAAGTTCATTCGCTTTTTCAGCAAGCTGCCCTGA
GATACTCAACGGCAAACAAAGGCTGTTAAATTCAAACGAAGAAATTGAGCTGTGTGAAGAGTTTCAAGGCAAGACTTTAT
TGATCGTGAATACGGCAAGCCAATGCGGTTTCACGCCTCAATTCGAACAACTTGAGCAGCTTCACCAAACGTATAAAGAT
GAAGGCTTCACGGTCGTTGGTTTCCCAAGTAATGATTTTCGCCAAGACAGAGGAAGCGAGAAGCAATCCGCTAAAATCTG
CTACCTAGATTATGGCGTCACCTTTCCAATGATGGCGCGCGCTTCACTCTCTGGGCCAGACGCAAACCCAGTCTTTGCCG
AAATCCAACAACAAGCCGGTATCAAACCAAAATGGAATTTCTACAAGTTCTTGGTCAGCAAAGAAGGCAAAGTGATAGCA
ACCTTCCCGAGTTCTACATCGCCAACCAGTAGTACCCTCAAAAATGCTATTGAGCAACAGTTATGA

Upstream 100 bases:

>100_bases
TAAGCGATAGCTGATACTTAAGCGATTCTGGTCTTTAAAGTGATCATTTCAAGTCGCTGAACAGTAATAACAGTTACGCT
AACTAAAATGAGTCGGACTT

Downstream 100 bases:

>100_bases
GGTCGGGTTACATGGAGACAACTCAAACACGCAACACCATGGCCAAGCTCGGTTATATGGGTTTAATCCCCTTTTTATTC
GGTCTACTATTATCACTCAC

Product: putative ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKHSLLCSTALIASLTSSFAFSASCPEILNGKQRLLNSNEEIELCEEFQGKTLLIVNTASQCGFTPQFEQLEQLHQTYKD
EGFTVVGFPSNDFRQDRGSEKQSAKICYLDYGVTFPMMARASLSGPDANPVFAEIQQQAGIKPKWNFYKFLVSKEGKVIA
TFPSSTSPTSSTLKNAIEQQL

Sequences:

>Translated_181_residues
MKHSLLCSTALIASLTSSFAFSASCPEILNGKQRLLNSNEEIELCEEFQGKTLLIVNTASQCGFTPQFEQLEQLHQTYKD
EGFTVVGFPSNDFRQDRGSEKQSAKICYLDYGVTFPMMARASLSGPDANPVFAEIQQQAGIKPKWNFYKFLVSKEGKVIA
TFPSSTSPTSSTLKNAIEQQL
>Mature_181_residues
MKHSLLCSTALIASLTSSFAFSASCPEILNGKQRLLNSNEEIELCEEFQGKTLLIVNTASQCGFTPQFEQLEQLHQTYKD
EGFTVVGFPSNDFRQDRGSEKQSAKICYLDYGVTFPMMARASLSGPDANPVFAEIQQQAGIKPKWNFYKFLVSKEGKVIA
TFPSSTSPTSSTLKNAIEQQL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=136, Percent_Identity=34.5588235294118, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI192455698, Length=116, Percent_Identity=33.6206896551724, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI75709200, Length=130, Percent_Identity=30, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI90903240, Length=130, Percent_Identity=30, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1788003, Length=166, Percent_Identity=34.9397590361446, Blast_Score=109, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17535473, Length=140, Percent_Identity=34.2857142857143, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17506887, Length=153, Percent_Identity=31.3725490196078, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71993584, Length=129, Percent_Identity=28.6821705426357, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322228, Length=142, Percent_Identity=47.1830985915493, Blast_Score=134, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6319721, Length=131, Percent_Identity=46.5648854961832, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322826, Length=126, Percent_Identity=40.4761904761905, Blast_Score=101, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24656772, Length=133, Percent_Identity=33.8345864661654, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24656767, Length=133, Percent_Identity=33.8345864661654, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24656777, Length=133, Percent_Identity=33.8345864661654, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 20037; Mature: 20037

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHSLLCSTALIASLTSSFAFSASCPEILNGKQRLLNSNEEIELCEEFQGKTLLIVNTAS
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHCCCCCHHHHHHCCCCEEEEEECHH
QCGFTPQFEQLEQLHQTYKDEGFTVVGFPSNDFRQDRGSEKQSAKICYLDYGVTFPMMAR
HCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCCCCCCEEEEEECCCCCHHHHH
ASLSGPDANPVFAEIQQQAGIKPKWNFYKFLVSKEGKVIATFPSSTSPTSSTLKNAIEQQ
CCCCCCCCCHHHHHHHHHCCCCCCCHHHEEEECCCCCEEEECCCCCCCHHHHHHHHHHHC
L
C
>Mature Secondary Structure
MKHSLLCSTALIASLTSSFAFSASCPEILNGKQRLLNSNEEIELCEEFQGKTLLIVNTAS
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHCCCCCHHHHHHCCCCEEEEEECHH
QCGFTPQFEQLEQLHQTYKDEGFTVVGFPSNDFRQDRGSEKQSAKICYLDYGVTFPMMAR
HCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCCCCCCEEEEEECCCCCHHHHH
ASLSGPDANPVFAEIQQQAGIKPKWNFYKFLVSKEGKVIATFPSSTSPTSSTLKNAIEQQ
CCCCCCCCCHHHHHHHHHCCCCCCCHHHEEEECCCCCEEEECCCCCCCHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA