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The map label for this gene is lpxH

Identifier: 218709997

GI number: 218709997

Start: 2162647

End: 2163381

Strand: Direct

Name: lpxH

Synonym: VS_2016

Alternate gene names: 218709997

Gene position: 2162647-2163381 (Clockwise)

Preceding gene: 218709996

Following gene: 218709998

Centisome position: 65.55

GC content: 40.68

Gene sequence:

>735_bases
ATGAAAACATATTTTATATCAGACCTACACCTTGCTCCGTCGCGACAAGACATCACAGACTGCTTCTTAACCTTCATGAA
GAATGAGGCCTTAGAAGCGGATGCACTCTACGTGTTGGGCGATCTTTTCGAATTCTGGATTGGTGACGACGATACAAGCG
AGTTCGCGAATTCAATTCGCCAAACGTTTATAGACTTAGTTAACACTGGCGTACCTTGTTATTTCACACAAGGCAATCGT
GACTTTTTAGTTGGCAAAAAATTTGCAAAACAAACAGGCGTACAACTTCTAGATGAAGTGTCTACTATCGATATCTACGG
ACAAAAAGCAGTGGTATTGCATGGTGATACTCTGTGTACCGAAGATATAAAGTACCTCGCCTTTCGTGAAAAAGTTCATC
AGCCCTGGTTACAATGGGTCTTTAATAGAATTCCATTTTTTATCAAAAAGAAAATTGTCTCCAAGGTTCAGTCTGATATC
AAAGATGACAAGCAGACAAAGTCACTCGATATCATGGATGTAACACAGCAAGAAGTCGAAAATGTGATGAAACAACACAA
CGTCGATTTGATGATCCACGGTCATACTCACCGTCCAAACATACACTCCTTTAGTGCCAATAATTGCACTAAAACCCGTA
TCGTATTGGGTGATTGGTATACCCAAGGATCCGTTCTGGTGTTCACTCCGCAAAGTTTTGAACTACAGAATCGCGAGTTT
AGCAATCGCTTTTAG

Upstream 100 bases:

>100_bases
CTACAATCGAAGCTTAATCACTTGCTTTCGGTTAGTATTAATAATTGATGAGCCGATAAAATCAGGATATAGGGAGCGAA
TCGCTCCTTTTTTTAGATCT

Downstream 100 bases:

>100_bases
CATCACGCTTAAACTTTCACTTTTATTATTATCATCGGTCAGATTTTCTTCACTTGTATATGGTAATTTCTCCTGAATTA
GCTATTATTTGTCTATCAAA

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MKTYFISDLHLAPSRQDITDCFLTFMKNEALEADALYVLGDLFEFWIGDDDTSEFANSIRQTFIDLVNTGVPCYFTQGNR
DFLVGKKFAKQTGVQLLDEVSTIDIYGQKAVVLHGDTLCTEDIKYLAFREKVHQPWLQWVFNRIPFFIKKKIVSKVQSDI
KDDKQTKSLDIMDVTQQEVENVMKQHNVDLMIHGHTHRPNIHSFSANNCTKTRIVLGDWYTQGSVLVFTPQSFELQNREF
SNRF

Sequences:

>Translated_244_residues
MKTYFISDLHLAPSRQDITDCFLTFMKNEALEADALYVLGDLFEFWIGDDDTSEFANSIRQTFIDLVNTGVPCYFTQGNR
DFLVGKKFAKQTGVQLLDEVSTIDIYGQKAVVLHGDTLCTEDIKYLAFREKVHQPWLQWVFNRIPFFIKKKIVSKVQSDI
KDDKQTKSLDIMDVTQQEVENVMKQHNVDLMIHGHTHRPNIHSFSANNCTKTRIVLGDWYTQGSVLVFTPQSFELQNREF
SNRF
>Mature_244_residues
MKTYFISDLHLAPSRQDITDCFLTFMKNEALEADALYVLGDLFEFWIGDDDTSEFANSIRQTFIDLVNTGVPCYFTQGNR
DFLVGKKFAKQTGVQLLDEVSTIDIYGQKAVVLHGDTLCTEDIKYLAFREKVHQPWLQWVFNRIPFFIKKKIVSKVQSDI
KDDKQTKSLDIMDVTQQEVENVMKQHNVDLMIHGHTHRPNIHSFSANNCTKTRIVLGDWYTQGSVLVFTPQSFELQNREF
SNRF

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family

Homologues:

Organism=Escherichia coli, GI1786735, Length=240, Percent_Identity=47.5, Blast_Score=258, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXH_VIBSL (B7VGZ3)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002417618.1
- GeneID:   7161572
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2016
- HOGENOM:   HBG288883
- OMA:   CHGDTLC
- GO:   GO:0005737
- HAMAP:   MF_00575
- InterPro:   IPR004843
- InterPro:   IPR010138
- TIGRFAMs:   TIGR01854

Pfam domain/function: PF00149 Metallophos

EC number: 3.6.1.-

Molecular weight: Translated: 28304; Mature: 28304

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYFISDLHLAPSRQDITDCFLTFMKNEALEADALYVLGDLFEFWIGDDDTSEFANSIR
CCEEEEECEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QTFIDLVNTGVPCYFTQGNRDFLVGKKFAKQTGVQLLDEVSTIDIYGQKAVVLHGDTLCT
HHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCCHHH
EDIKYLAFREKVHQPWLQWVFNRIPFFIKKKIVSKVQSDIKDDKQTKSLDIMDVTQQEVE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHH
NVMKQHNVDLMIHGHTHRPNIHSFSANNCTKTRIVLGDWYTQGSVLVFTPQSFELQNREF
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCCCCCCC
SNRF
CCCC
>Mature Secondary Structure
MKTYFISDLHLAPSRQDITDCFLTFMKNEALEADALYVLGDLFEFWIGDDDTSEFANSIR
CCEEEEECEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QTFIDLVNTGVPCYFTQGNRDFLVGKKFAKQTGVQLLDEVSTIDIYGQKAVVLHGDTLCT
HHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCCHHH
EDIKYLAFREKVHQPWLQWVFNRIPFFIKKKIVSKVQSDIKDDKQTKSLDIMDVTQQEVE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHH
NVMKQHNVDLMIHGHTHRPNIHSFSANNCTKTRIVLGDWYTQGSVLVFTPQSFELQNREF
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCCCCCCC
SNRF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA