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The map label for this gene is tdk [H]

Identifier: 218709994

GI number: 218709994

Start: 2159817

End: 2160395

Strand: Reverse

Name: tdk [H]

Synonym: VS_2013

Alternate gene names: 218709994

Gene position: 2160395-2159817 (Counterclockwise)

Preceding gene: 218709995

Following gene: 218709990

Centisome position: 65.48

GC content: 41.62

Gene sequence:

>579_bases
GTGGCTCAGATGTATTTTTATTACTCGGCAATGAACGCGGGTAAATCAACAACGCTTCTTCAATCTTCATTCAACTACCA
AGAACGTGGTATGACACCAGTGATCTTTACGGCTGCATTAGATGATCGCTATGGTATCGGTAAAGTGAGTTCACGAATTG
GTCTTCAATCTGAAGCTCAATTGTTTAAAAACGACACCAATATGTTTGAGGCAATTCAAAAACTCAACGAAGAAGAAAAG
CGTCATTGTGTATTGATCGATGAGTGTCAGTTTTTGTCGAAAGAGCAGGTTTACCAACTAACAGAAGTGGTTGATAAGCT
GCACATCCCTGTACTTTGCTACGGTTTGCGCACTGACTTCTTGGGTGAACTGTTTGAAGGTAGCCGCTACTTGTTGTCTT
GGGCTGACAAATTAGTAGAACTTAAAACAATTTGCCACTGTGGCCGTAAGGCCAATATGGTAATTCGTACAGATGAGCAC
GGTGTGGCAATTGCTGAAGGTGACCAAGTCGCTATTGGTGGCAATGACCAATATGTTTCGGCTTGCCGTTTACATTATAA
AGAAGCGTTAGGTAAATAA

Upstream 100 bases:

>100_bases
TAAATCTTATAAAAAGGGCTGATTTTCAGCCCTTTTTTCTAGCAAAAATTCTCTAATTTCACCTTTTTATCTTCAACTTT
TAATTAACAGGAATATTTCT

Downstream 100 bases:

>100_bases
GCAGCCTACAAGTCGGCATTGCTAAAACCAATAGCGTTCAAATTAGAAAACGGTGACCTAGTGTCACCGTTTTTGTTTAT
TGAGCCGAGCTTTTGTTTTA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MAQMYFYYSAMNAGKSTTLLQSSFNYQERGMTPVIFTAALDDRYGIGKVSSRIGLQSEAQLFKNDTNMFEAIQKLNEEEK
RHCVLIDECQFLSKEQVYQLTEVVDKLHIPVLCYGLRTDFLGELFEGSRYLLSWADKLVELKTICHCGRKANMVIRTDEH
GVAIAEGDQVAIGGNDQYVSACRLHYKEALGK

Sequences:

>Translated_192_residues
MAQMYFYYSAMNAGKSTTLLQSSFNYQERGMTPVIFTAALDDRYGIGKVSSRIGLQSEAQLFKNDTNMFEAIQKLNEEEK
RHCVLIDECQFLSKEQVYQLTEVVDKLHIPVLCYGLRTDFLGELFEGSRYLLSWADKLVELKTICHCGRKANMVIRTDEH
GVAIAEGDQVAIGGNDQYVSACRLHYKEALGK
>Mature_191_residues
AQMYFYYSAMNAGKSTTLLQSSFNYQERGMTPVIFTAALDDRYGIGKVSSRIGLQSEAQLFKNDTNMFEAIQKLNEEEKR
HCVLIDECQFLSKEQVYQLTEVVDKLHIPVLCYGLRTDFLGELFEGSRYLLSWADKLVELKTICHCGRKANMVIRTDEHG
VAIAEGDQVAIGGNDQYVSACRLHYKEALGK

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=190, Percent_Identity=68.9473684210526, Blast_Score=286, Evalue=5e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21785; Mature: 21654

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQMYFYYSAMNAGKSTTLLQSSFNYQERGMTPVIFTAALDDRYGIGKVSSRIGLQSEAQ
CCEEEEEEEECCCCCCHHHHHHCCCHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCHHHH
LFKNDTNMFEAIQKLNEEEKRHCVLIDECQFLSKEQVYQLTEVVDKLHIPVLCYGLRTDF
HHHCCCHHHHHHHHHCHHHHHCEEEEHHHHHCCHHHHHHHHHHHHHHCCCCEEEHHHHHH
LGELFEGSRYLLSWADKLVELKTICHCGRKANMVIRTDEHGVAIAEGDQVAIGGNDQYVS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCEEEECCCCHHHH
ACRLHYKEALGK
HHHHHHHHHHCC
>Mature Secondary Structure 
AQMYFYYSAMNAGKSTTLLQSSFNYQERGMTPVIFTAALDDRYGIGKVSSRIGLQSEAQ
CEEEEEEEECCCCCCHHHHHHCCCHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCHHHH
LFKNDTNMFEAIQKLNEEEKRHCVLIDECQFLSKEQVYQLTEVVDKLHIPVLCYGLRTDF
HHHCCCHHHHHHHHHCHHHHHCEEEEHHHHHCCHHHHHHHHHHHHHHCCCCEEEHHHHHH
LGELFEGSRYLLSWADKLVELKTICHCGRKANMVIRTDEHGVAIAEGDQVAIGGNDQYVS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCEEEECCCCHHHH
ACRLHYKEALGK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]