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The map label for this gene is nreB [H]

Identifier: 218709898

GI number: 218709898

Start: 2053954

End: 2055309

Strand: Reverse

Name: nreB [H]

Synonym: VS_1911

Alternate gene names: 218709898

Gene position: 2055309-2053954 (Counterclockwise)

Preceding gene: 218709899

Following gene: 218709897

Centisome position: 62.3

GC content: 44.62

Gene sequence:

>1356_bases
ATGCCTCTAAAAGTTAAGCTGATTTTGCTGACGCTACTCCCGTTGCTGATTGTAACGGCGAGCATTAGTTGGATCTCGTT
ACACCAAACTAAGACGTTGGGTGAGAAAGAGGTCGAAATCTTCCGAGACAGCTTAATTAAGTCGCGTGAAAACGCCCTCA
AAGACACTGTTGATCTTGCATTTGATGCCATCGAACATATCTACAATGATCCCGATATCCAAGAAGCACAAGCCAAAAGA
GAAGTTCGAACCATATTGTCTAAACTAAGGTATGGCTCTGACGGTTACTTCTTTGCGTATGATCGCCACGGAACCAATTT
GGTTCATCCAATCCAGCCAGAGTTGATAGGGCAAAACTTACTTCAACTGCAAGATGAAGATGGCGACTTTCTGATAGAAG
CCTTGTTAAGAGAAGCACAAACAGGCGGAGGATTTCACCAATATTTGTGGCAAAAACCTTCGACAGGTGAGGTGGTATCG
AAGCTGAGTTACGCCGCTTGGTTAGAGCGCTGGGACTGGATGATTGGCACCGGCTTGTATATTGAGGATGTGCATCAAGA
AGTGGCCTCGATGCAGGCCGCAATTAACAAGAATATTGAAACCACGTTCTTTTCGATTGTGGTGATTCTGAGTGTGACGG
TCGCGGTCATCATTGTACTGACGTTGGCCATTAACATGCATGAACATCGGATAGCGGATAACAACTTGAAGGAACTAGCT
CATAAGACGGTGATGTTTCAAGAGGACGAAAAGAAGCATCTAGCGCGTGAGTTGCATGATGGTATTAACCAGTTATTAGT
GTCGAGTCGCTGTCACTTAGAACTGCTCGGTAATAAGCTACAAAGCGAAGACCTTAAAGTGCATTTGAATAAGTCTCAGC
ATTCACTGATGCGGGCAATCGAAGAGGTGAGGCATATTTCGCATCAACTTCGACCAAGTTCATTGGATGATATCGGCTTA
GAAGCGGCGTTGTCTTCGCTGTTATTAGACTTTCAGGCGCACTCGAGCATTGAAGTGGAAACCTTGTTTAATACGCAGCC
GGGAAAGTTGAAATCAGAAGCTGCGACGACTTTATATCGAGTGGTGCAAGAGTCACTGAATAATATAGAGAAACACGCAC
AAGCGACCAAAGTAACGGTTATCGCACAGCAAATTGGAAATGTGTTGCAGTTGCTCATCCAAGACGATGGAGTCGGTTTC
AATACCTATAAAGCAATGGAAAAGCGAGGTATTGGGTTACGTAACATGAGAGAACGGGTGGAGTTCATCGGTGGTGACTT
TGAATTGATGAGTGAGGTTGGCTTTGGAACGGAAATTACAGTGTTACTGACACTAGAGGGATTAGTGAATGAGTGA

Upstream 100 bases:

>100_bases
AGCCTAGAATGTGAATGATATGTTTCAACGGCTATCCATAAATTGATAAAGTAAAACGGCTTATTGATGTTCAATAAGCC
GTTTTTTGTGAGGAAAAGGA

Downstream 100 bases:

>100_bases
AGTTATTCGAGTTGTGATTGCAGATGATCACCAAGTGGTACTGGATGGCTTTATGGCGAGATTAGAACTCGAGCCTGATA
TTAGCGTGATAGGTACAGCC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MPLKVKLILLTLLPLLIVTASISWISLHQTKTLGEKEVEIFRDSLIKSRENALKDTVDLAFDAIEHIYNDPDIQEAQAKR
EVRTILSKLRYGSDGYFFAYDRHGTNLVHPIQPELIGQNLLQLQDEDGDFLIEALLREAQTGGGFHQYLWQKPSTGEVVS
KLSYAAWLERWDWMIGTGLYIEDVHQEVASMQAAINKNIETTFFSIVVILSVTVAVIIVLTLAINMHEHRIADNNLKELA
HKTVMFQEDEKKHLARELHDGINQLLVSSRCHLELLGNKLQSEDLKVHLNKSQHSLMRAIEEVRHISHQLRPSSLDDIGL
EAALSSLLLDFQAHSSIEVETLFNTQPGKLKSEAATTLYRVVQESLNNIEKHAQATKVTVIAQQIGNVLQLLIQDDGVGF
NTYKAMEKRGIGLRNMRERVEFIGGDFELMSEVGFGTEITVLLTLEGLVNE

Sequences:

>Translated_451_residues
MPLKVKLILLTLLPLLIVTASISWISLHQTKTLGEKEVEIFRDSLIKSRENALKDTVDLAFDAIEHIYNDPDIQEAQAKR
EVRTILSKLRYGSDGYFFAYDRHGTNLVHPIQPELIGQNLLQLQDEDGDFLIEALLREAQTGGGFHQYLWQKPSTGEVVS
KLSYAAWLERWDWMIGTGLYIEDVHQEVASMQAAINKNIETTFFSIVVILSVTVAVIIVLTLAINMHEHRIADNNLKELA
HKTVMFQEDEKKHLARELHDGINQLLVSSRCHLELLGNKLQSEDLKVHLNKSQHSLMRAIEEVRHISHQLRPSSLDDIGL
EAALSSLLLDFQAHSSIEVETLFNTQPGKLKSEAATTLYRVVQESLNNIEKHAQATKVTVIAQQIGNVLQLLIQDDGVGF
NTYKAMEKRGIGLRNMRERVEFIGGDFELMSEVGFGTEITVLLTLEGLVNE
>Mature_450_residues
PLKVKLILLTLLPLLIVTASISWISLHQTKTLGEKEVEIFRDSLIKSRENALKDTVDLAFDAIEHIYNDPDIQEAQAKRE
VRTILSKLRYGSDGYFFAYDRHGTNLVHPIQPELIGQNLLQLQDEDGDFLIEALLREAQTGGGFHQYLWQKPSTGEVVSK
LSYAAWLERWDWMIGTGLYIEDVHQEVASMQAAINKNIETTFFSIVVILSVTVAVIIVLTLAINMHEHRIADNNLKELAH
KTVMFQEDEKKHLARELHDGINQLLVSSRCHLELLGNKLQSEDLKVHLNKSQHSLMRAIEEVRHISHQLRPSSLDDIGLE
AALSSLLLDFQAHSSIEVETLFNTQPGKLKSEAATTLYRVVQESLNNIEKHAQATKVTVIAQQIGNVLQLLIQDDGVGFN
TYKAMEKRGIGLRNMRERVEFIGGDFELMSEVGFGTEITVLLTLEGLVNE

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=210, Percent_Identity=32.3809523809524, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787474, Length=232, Percent_Identity=26.7241379310345, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50926; Mature: 50795

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKVKLILLTLLPLLIVTASISWISLHQTKTLGEKEVEIFRDSLIKSRENALKDTVDLA
CCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FDAIEHIYNDPDIQEAQAKREVRTILSKLRYGSDGYFFAYDRHGTNLVHPIQPELIGQNL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHCCHH
LQLQDEDGDFLIEALLREAQTGGGFHQYLWQKPSTGEVVSKLSYAAWLERWDWMIGTGLY
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
IEDVHQEVASMQAAINKNIETTFFSIVVILSVTVAVIIVLTLAINMHEHRIADNNLKELA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
HKTVMFQEDEKKHLARELHDGINQLLVSSRCHLELLGNKLQSEDLKVHLNKSQHSLMRAI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHCCCCEEEEECCHHHHHHHHH
EEVRHISHQLRPSSLDDIGLEAALSSLLLDFQAHSSIEVETLFNTQPGKLKSEAATTLYR
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHH
VVQESLNNIEKHAQATKVTVIAQQIGNVLQLLIQDDGVGFNTYKAMEKRGIGLRNMRERV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHH
EFIGGDFELMSEVGFGTEITVLLTLEGLVNE
HHHCCCHHHHHHCCCCCEEEEEEEECHHHCC
>Mature Secondary Structure 
PLKVKLILLTLLPLLIVTASISWISLHQTKTLGEKEVEIFRDSLIKSRENALKDTVDLA
CEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FDAIEHIYNDPDIQEAQAKREVRTILSKLRYGSDGYFFAYDRHGTNLVHPIQPELIGQNL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHCCHH
LQLQDEDGDFLIEALLREAQTGGGFHQYLWQKPSTGEVVSKLSYAAWLERWDWMIGTGLY
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
IEDVHQEVASMQAAINKNIETTFFSIVVILSVTVAVIIVLTLAINMHEHRIADNNLKELA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
HKTVMFQEDEKKHLARELHDGINQLLVSSRCHLELLGNKLQSEDLKVHLNKSQHSLMRAI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHCCCCEEEEECCHHHHHHHHH
EEVRHISHQLRPSSLDDIGLEAALSSLLLDFQAHSSIEVETLFNTQPGKLKSEAATTLYR
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHH
VVQESLNNIEKHAQATKVTVIAQQIGNVLQLLIQDDGVGFNTYKAMEKRGIGLRNMRERV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHH
EFIGGDFELMSEVGFGTEITVLLTLEGLVNE
HHHCCCHHHHHHCCCCCEEEEEEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]