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The map label for this gene is nreC [H]

Identifier: 218709897

GI number: 218709897

Start: 2053323

End: 2053961

Strand: Reverse

Name: nreC [H]

Synonym: VS_1910

Alternate gene names: 218709897

Gene position: 2053961-2053323 (Counterclockwise)

Preceding gene: 218709898

Following gene: 218709896

Centisome position: 62.25

GC content: 43.97

Gene sequence:

>639_bases
ATGAGTGAAGTTATTCGAGTTGTGATTGCAGATGATCACCAAGTGGTACTGGATGGCTTTATGGCGAGATTAGAACTCGA
GCCTGATATTAGCGTGATAGGTACAGCCAGCAATGGATTAGAAGCCGTTGAAGTGGTTAAAGACTTGCGCCCTGATGTAG
TGTTGATGGATATCAGCATGCCTATCATGAATGGTATTGATGCCACTCACCTGATTAAAGAGGAAGATCCTCAAGCTAAG
GTGCTGATGCTGACCATGCATAACAACCGTGAATACATCATGAAGGTGATGCAATCGGGTGCTGTCGGCTATATGTTGAA
AGAAATTTCGGCTGAAAAAATGGTGCAGGCAATCAAGACGGTCAATCAAGGCTCAACCTATTTCTGTGAAAAAGTGACTC
AGAACTTGTTTACTCAGCCTATTACTCCCACACAATCTGTGAAGAACCCATTGAGTAGGCGTGAGGAAGCTGTGTTGAAA
TTAGTGGCTAAAGGGGAGAGCAGTAAAGAGATCGCGAAGGGATTAAATATCAGTTACCGAACGGTTGAAACCCATAGACA
AAATATCAAGCATAAGCTCGACATTCACTCTACGGCAGAGCTTGCCAAGTATGCTGTTAGCTCTGGGCTTGTTGAGTGA

Upstream 100 bases:

>100_bases
AGAGAACGGGTGGAGTTCATCGGTGGTGACTTTGAATTGATGAGTGAGGTTGGCTTTGGAACGGAAATTACAGTGTTACT
GACACTAGAGGGATTAGTGA

Downstream 100 bases:

>100_bases
TGTTACGCTAAATTACAGTGAATGTGTAATTTAATTACCAAATGTGCCGTTTACACCCGTTTTTTGATGGTTTTTTTAGT
ATTTTTGCGACGAGTTGTTA

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSEVIRVVIADDHQVVLDGFMARLELEPDISVIGTASNGLEAVEVVKDLRPDVVLMDISMPIMNGIDATHLIKEEDPQAK
VLMLTMHNNREYIMKVMQSGAVGYMLKEISAEKMVQAIKTVNQGSTYFCEKVTQNLFTQPITPTQSVKNPLSRREEAVLK
LVAKGESSKEIAKGLNISYRTVETHRQNIKHKLDIHSTAELAKYAVSSGLVE

Sequences:

>Translated_212_residues
MSEVIRVVIADDHQVVLDGFMARLELEPDISVIGTASNGLEAVEVVKDLRPDVVLMDISMPIMNGIDATHLIKEEDPQAK
VLMLTMHNNREYIMKVMQSGAVGYMLKEISAEKMVQAIKTVNQGSTYFCEKVTQNLFTQPITPTQSVKNPLSRREEAVLK
LVAKGESSKEIAKGLNISYRTVETHRQNIKHKLDIHSTAELAKYAVSSGLVE
>Mature_211_residues
SEVIRVVIADDHQVVLDGFMARLELEPDISVIGTASNGLEAVEVVKDLRPDVVLMDISMPIMNGIDATHLIKEEDPQAKV
LMLTMHNNREYIMKVMQSGAVGYMLKEISAEKMVQAIKTVNQGSTYFCEKVTQNLFTQPITPTQSVKNPLSRREEAVLKL
VAKGESSKEIAKGLNISYRTVETHRQNIKHKLDIHSTAELAKYAVSSGLVE

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=210, Percent_Identity=37.1428571428571, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=33.1632653061224, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=31, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=31.6939890710383, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788712, Length=198, Percent_Identity=26.2626262626263, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786747, Length=199, Percent_Identity=27.1356783919598, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1788546, Length=206, Percent_Identity=29.126213592233, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87082052, Length=120, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23564; Mature: 23432

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVIRVVIADDHQVVLDGFMARLELEPDISVIGTASNGLEAVEVVKDLRPDVVLMDISM
CCCCEEEEEECCCHHHHHHHHHHEECCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECC
PIMNGIDATHLIKEEDPQAKVLMLTMHNNREYIMKVMQSGAVGYMLKEISAEKMVQAIKT
HHHCCCCHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VNQGSTYFCEKVTQNLFTQPITPTQSVKNPLSRREEAVLKLVAKGESSKEIAKGLNISYR
HCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEE
TVETHRQNIKHKLDIHSTAELAKYAVSSGLVE
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEVIRVVIADDHQVVLDGFMARLELEPDISVIGTASNGLEAVEVVKDLRPDVVLMDISM
CCCEEEEEECCCHHHHHHHHHHEECCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECC
PIMNGIDATHLIKEEDPQAKVLMLTMHNNREYIMKVMQSGAVGYMLKEISAEKMVQAIKT
HHHCCCCHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VNQGSTYFCEKVTQNLFTQPITPTQSVKNPLSRREEAVLKLVAKGESSKEIAKGLNISYR
HCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEE
TVETHRQNIKHKLDIHSTAELAKYAVSSGLVE
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA