Click here to switch to the map view.

The map label for this gene is sufB [H]

Identifier: 218709889

GI number: 218709889

Start: 2042201

End: 2043793

Strand: Direct

Name: sufB [H]

Synonym: VS_1902

Alternate gene names: 218709889

Gene position: 2042201-2043793 (Clockwise)

Preceding gene: 218709888

Following gene: 218709890

Centisome position: 61.9

GC content: 45.32

Gene sequence:

>1593_bases
ATGTGGCGAGAGTTTTGGAGTTTAACCATGTGCGCATTAGAAACGCAGTCTGAAGCTAAAACGCTACTTGACGTTGAAAC
GCAAACAAAAATTGAAATGCGACCAGACGCTGAAACGCGACCTGAAATTGACACGCAGCCTGAAGTTACAGAGCTGCTGC
AGAGCGGCCACTATCGTGAAGGTTTCTACACTGAGTTATCTTCAGATACTTTGTCGAAGGGAATCAACGAACAAGTCGTT
CGAGCAATCTCCGCAAAACGTAACGAACCCGAATGGATGTTGGAGTTTCGTCTCAAAGCATTCCGTAAATGGCGAACAAT
GGAGGAACCGCATTGGTTAAAAGCCGATTATCCAGACCTAAATTACCAAGATTACAGTTACTACTCCGCGCCAAGTTGTT
CTAGCTGCGACAAAGATAGTTGTGACAAAGATAGTGATGATGGCTCGAATGAATTTTTAACCGAAGAAGTCGAGACAGCC
TTTGAAACACTGGGGATTCCAGTTAGGGAAGGTTCAGAAATTGCTGTTGATGCAATCTTCGATTCAGTTTCCGTCACCAC
TACCTATCAAAACGAACTGAAAGAACTCGGGATCATCTTCTGTTCATTCAGCGAAGCAATCCAAGAATACCCTGAACTTG
TGCAGCAATACTTAGGCACCGTTGTTCCACCTGAAGATAACTTCTTTGCAGCTTTGAATGCCTCTGTTGCCTCTGACGGC
ACTTTTGTTTACATCCCTAAAGGTGTGAGATGCCCAAGAGAACTCTCTACCTACTTTCGAATAAACCAAGCAAAAACAGG
CCAGTTTGAAAGAACAATTTTAGTGGCTGATGAGGACTCATACGTCAGCTACATTGAAGGTTGCTCTGCCCCGATGAGAG
ATACCTATCAGCTTCACGCCGCCGTCGTAGAAGTCATCATTCACAAGCGTGCTGAAGTTAAATATTCCACAGTCCAAAAC
TGGTTCTCGGGAGCAGAGGATTCACAAGGCGGCATACTCAATTTCGTAACCAAACGTGCGGTTTGCGAAGGCGAGTACAG
CAAAATGTCTTGGACTCAATCAGAAACAGGTTCTGCGATAACGTGGAAGTATCCAAGCGTGATTCTCAAAGGAGACTACT
CTGTTGGTGAGTTTTTCTCCGTCGCTCTAACAAATGGCGTTCAACAGGCCGATACCGGCACCAAGATGGTTCATATAGGA
AAACACTCTCGCTCTACCATCATTTCAAAAGGGATTTCAGCAGGCAAAAGCCAGAACAGTTACCGAGGGCTGGTTAAAGT
CACCCCTAACGCAGAAGGTGCGAGAAACTTCACTCAGTGCGATTCAATGTTAATCGGCGCTGAATGTGGGGCTCACACTT
TTCCTTATATCGAAGTCAAAAACCCGTCGGCTCACGTTGAACACGAAGCGACGACCTCTCGAATTGGCCAAGATCAACTG
TTTTACTGCACCCAAAGAGGGATCAGTGAAGACAACGCCATATCCATGATCGTCAATGGTTTTTGTAAAGACGTATTTTC
AGAATTACCACTCGAATTCGCTGTTGAAGCGCAGAAACTTCTATCAATCAGCCTCGAGCATAGTGTGGGATAA

Upstream 100 bases:

>100_bases
AAGCCCTACCTATGATCGATGGCACAGAGATCGACTTTGTGCGTCAGGGTTTAAACAGTAATTTTGTATACAATAATCCC
AAAGTGAAGAACCTTTGTGG

Downstream 100 bases:

>100_bases
AATGTTAGAAATTAAAAATTTACATGTCAGCGTTGAAGAAAATACTATCCTAAAAGGTATTAACCTAACCGTTAAACCTG
GTGAAGTTCACGCAATTATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MWREFWSLTMCALETQSEAKTLLDVETQTKIEMRPDAETRPEIDTQPEVTELLQSGHYREGFYTELSSDTLSKGINEQVV
RAISAKRNEPEWMLEFRLKAFRKWRTMEEPHWLKADYPDLNYQDYSYYSAPSCSSCDKDSCDKDSDDGSNEFLTEEVETA
FETLGIPVREGSEIAVDAIFDSVSVTTTYQNELKELGIIFCSFSEAIQEYPELVQQYLGTVVPPEDNFFAALNASVASDG
TFVYIPKGVRCPRELSTYFRINQAKTGQFERTILVADEDSYVSYIEGCSAPMRDTYQLHAAVVEVIIHKRAEVKYSTVQN
WFSGAEDSQGGILNFVTKRAVCEGEYSKMSWTQSETGSAITWKYPSVILKGDYSVGEFFSVALTNGVQQADTGTKMVHIG
KHSRSTIISKGISAGKSQNSYRGLVKVTPNAEGARNFTQCDSMLIGAECGAHTFPYIEVKNPSAHVEHEATTSRIGQDQL
FYCTQRGISEDNAISMIVNGFCKDVFSELPLEFAVEAQKLLSISLEHSVG

Sequences:

>Translated_530_residues
MWREFWSLTMCALETQSEAKTLLDVETQTKIEMRPDAETRPEIDTQPEVTELLQSGHYREGFYTELSSDTLSKGINEQVV
RAISAKRNEPEWMLEFRLKAFRKWRTMEEPHWLKADYPDLNYQDYSYYSAPSCSSCDKDSCDKDSDDGSNEFLTEEVETA
FETLGIPVREGSEIAVDAIFDSVSVTTTYQNELKELGIIFCSFSEAIQEYPELVQQYLGTVVPPEDNFFAALNASVASDG
TFVYIPKGVRCPRELSTYFRINQAKTGQFERTILVADEDSYVSYIEGCSAPMRDTYQLHAAVVEVIIHKRAEVKYSTVQN
WFSGAEDSQGGILNFVTKRAVCEGEYSKMSWTQSETGSAITWKYPSVILKGDYSVGEFFSVALTNGVQQADTGTKMVHIG
KHSRSTIISKGISAGKSQNSYRGLVKVTPNAEGARNFTQCDSMLIGAECGAHTFPYIEVKNPSAHVEHEATTSRIGQDQL
FYCTQRGISEDNAISMIVNGFCKDVFSELPLEFAVEAQKLLSISLEHSVG
>Mature_530_residues
MWREFWSLTMCALETQSEAKTLLDVETQTKIEMRPDAETRPEIDTQPEVTELLQSGHYREGFYTELSSDTLSKGINEQVV
RAISAKRNEPEWMLEFRLKAFRKWRTMEEPHWLKADYPDLNYQDYSYYSAPSCSSCDKDSCDKDSDDGSNEFLTEEVETA
FETLGIPVREGSEIAVDAIFDSVSVTTTYQNELKELGIIFCSFSEAIQEYPELVQQYLGTVVPPEDNFFAALNASVASDG
TFVYIPKGVRCPRELSTYFRINQAKTGQFERTILVADEDSYVSYIEGCSAPMRDTYQLHAAVVEVIIHKRAEVKYSTVQN
WFSGAEDSQGGILNFVTKRAVCEGEYSKMSWTQSETGSAITWKYPSVILKGDYSVGEFFSVALTNGVQQADTGTKMVHIG
KHSRSTIISKGISAGKSQNSYRGLVKVTPNAEGARNFTQCDSMLIGAECGAHTFPYIEVKNPSAHVEHEATTSRIGQDQL
FYCTQRGISEDNAISMIVNGFCKDVFSELPLEFAVEAQKLLSISLEHSVG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=478, Percent_Identity=79.0794979079498, Blast_Score=799, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010231
- InterPro:   IPR000825 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 59408; Mature: 59408

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWREFWSLTMCALETQSEAKTLLDVETQTKIEMRPDAETRPEIDTQPEVTELLQSGHYRE
CCHHHHHHHHHHHCCHHHHHHHEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCC
GFYTELSSDTLSKGINEQVVRAISAKRNEPEWMLEFRLKAFRKWRTMEEPHWLKADYPDL
CCHHHCCHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCC
NYQDYSYYSAPSCSSCDKDSCDKDSDDGSNEFLTEEVETAFETLGIPVREGSEIAVDAIF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEHH
DSVSVTTTYQNELKELGIIFCSFSEAIQEYPELVQQYLGTVVPPEDNFFAALNASVASDG
CCEEEEEHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
TFVYIPKGVRCPRELSTYFRINQAKTGQFERTILVADEDSYVSYIEGCSAPMRDTYQLHA
CEEEECCCCCCHHHHHHHEEECCCCCCCCEEEEEEECCCCHHHHHHCCCCCCHHHHHHHH
AVVEVIIHKRAEVKYSTVQNWFSGAEDSQGGILNFVTKRAVCEGEYSKMSWTQSETGSAI
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCEE
TWKYPSVILKGDYSVGEFFSVALTNGVQQADTGTKMVHIGKHSRSTIISKGISAGKSQNS
EEECCEEEEECCCCHHHHHHHHHHCCCHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCC
YRGLVKVTPNAEGARNFTQCDSMLIGAECGAHTFPYIEVKNPSAHVEHEATTSRIGQDQL
CCCEEEECCCCCCCCCHHHHHHEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCE
FYCTQRGISEDNAISMIVNGFCKDVFSELPLEFAVEAQKLLSISLEHSVG
EHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MWREFWSLTMCALETQSEAKTLLDVETQTKIEMRPDAETRPEIDTQPEVTELLQSGHYRE
CCHHHHHHHHHHHCCHHHHHHHEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCC
GFYTELSSDTLSKGINEQVVRAISAKRNEPEWMLEFRLKAFRKWRTMEEPHWLKADYPDL
CCHHHCCHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCC
NYQDYSYYSAPSCSSCDKDSCDKDSDDGSNEFLTEEVETAFETLGIPVREGSEIAVDAIF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEHH
DSVSVTTTYQNELKELGIIFCSFSEAIQEYPELVQQYLGTVVPPEDNFFAALNASVASDG
CCEEEEEHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
TFVYIPKGVRCPRELSTYFRINQAKTGQFERTILVADEDSYVSYIEGCSAPMRDTYQLHA
CEEEECCCCCCHHHHHHHEEECCCCCCCCEEEEEEECCCCHHHHHHCCCCCCHHHHHHHH
AVVEVIIHKRAEVKYSTVQNWFSGAEDSQGGILNFVTKRAVCEGEYSKMSWTQSETGSAI
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCEE
TWKYPSVILKGDYSVGEFFSVALTNGVQQADTGTKMVHIGKHSRSTIISKGISAGKSQNS
EEECCEEEEECCCCHHHHHHHHHHCCCHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCC
YRGLVKVTPNAEGARNFTQCDSMLIGAECGAHTFPYIEVKNPSAHVEHEATTSRIGQDQL
CCCEEEECCCCCCCCCHHHHHHEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCE
FYCTQRGISEDNAISMIVNGFCKDVFSELPLEFAVEAQKLLSISLEHSVG
EHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]