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The map label for this gene is kefA [C]

Identifier: 218709487

GI number: 218709487

Start: 1629508

End: 1630395

Strand: Direct

Name: kefA [C]

Synonym: VS_1496

Alternate gene names: 218709487

Gene position: 1629508-1630395 (Clockwise)

Preceding gene: 218709486

Following gene: 218709490

Centisome position: 49.39

GC content: 45.95

Gene sequence:

>888_bases
ATGAAGAAGTTATTTATCCTACTATTTGTTGGCTTGGCAAGTGCTGTCAGTTTCCCGACCTTTGCGACGGAAGAGTTAGC
CAACGTAGAAAGCATCTCTAAGATAGCGAGCTTGGTGCGATGGAGCGGCGTGTTCTTCTCCATGATCGTTATTGCCGCAA
TGTGGTTGTTGCTTAAGTTCATCAATTCGTTAGTGACCAGTTTTGGTAGTCAGTTCGTGCAATATCGAATGCTGCTACAA
AAACTGCAATCGTTTACTCAGTTCTTTATCTACGTGAGCACAGGTCTTATCGTGTTCATGATGAGCTTTAGAATCAACGA
CCAAATCTTAGCTTTGATTGGTGGTACCCTCGCCGTGTCGGTCGGCTTTGCGCTTAAAGACTTGGCAGCATCGTTTATCG
CCGGCATCACTGTGATGATTGACAGACCCTTTCAGGTTGGTGACCGCGTCACGTTCGAAGGCAACTACGGCGACATCATC
ACCATTGGTTTACGTTCGGTACGAATGAGAACCCTGAACGATGACATCATTACTATTCCGAACAACAAGTTCTTAAATGA
AGTGACCACCAGTGGTAACTATGGCGCATTGGACATGCAAGTGGTGATTCCGTTTTACGTCGGTATGAATGAAGACATCA
CCCTAGCCCGCGACTTGATTCAAGAAGCCGCGTCTTCAAGTCGTTACATACACTTGCCAAAGCCTGTAACGGTTCTGGTT
AAACAGACGATTACCGACAACTACCTAGCGATACAGTTGACGTGTAAGGCTTATGTGGTGGACACCGCGTATGAGAAATT
GTTTGAAACCGACATTACCCTGCGTGTGATGAAAGAGTTTAAGAAGCACAACATCAACCCACCGAAGATTTCAGTGGCAG
CGCATTAG

Upstream 100 bases:

>100_bases
GGTTATATTGGTTGGCATGAAGAAAAGGCTCGAATTTCCGAGCACTGGTTCCGCCACATTACTAACGTTCTTGATCGTCA
ACATCTACTGGTGAAGTAAA

Downstream 100 bases:

>100_bases
GCTTAACGGTTTTCATGTTTTGGACGCTCGTAATCGTTTGAAATAACGGCCATAAATAAAAACACCTCCGAACTTATCTT
AAGTACGGAGGTGTTTTCTA

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKKLFILLFVGLASAVSFPTFATEELANVESISKIASLVRWSGVFFSMIVIAAMWLLLKFINSLVTSFGSQFVQYRMLLQ
KLQSFTQFFIYVSTGLIVFMMSFRINDQILALIGGTLAVSVGFALKDLAASFIAGITVMIDRPFQVGDRVTFEGNYGDII
TIGLRSVRMRTLNDDIITIPNNKFLNEVTTSGNYGALDMQVVIPFYVGMNEDITLARDLIQEAASSSRYIHLPKPVTVLV
KQTITDNYLAIQLTCKAYVVDTAYEKLFETDITLRVMKEFKKHNINPPKISVAAH

Sequences:

>Translated_295_residues
MKKLFILLFVGLASAVSFPTFATEELANVESISKIASLVRWSGVFFSMIVIAAMWLLLKFINSLVTSFGSQFVQYRMLLQ
KLQSFTQFFIYVSTGLIVFMMSFRINDQILALIGGTLAVSVGFALKDLAASFIAGITVMIDRPFQVGDRVTFEGNYGDII
TIGLRSVRMRTLNDDIITIPNNKFLNEVTTSGNYGALDMQVVIPFYVGMNEDITLARDLIQEAASSSRYIHLPKPVTVLV
KQTITDNYLAIQLTCKAYVVDTAYEKLFETDITLRVMKEFKKHNINPPKISVAAH
>Mature_295_residues
MKKLFILLFVGLASAVSFPTFATEELANVESISKIASLVRWSGVFFSMIVIAAMWLLLKFINSLVTSFGSQFVQYRMLLQ
KLQSFTQFFIYVSTGLIVFMMSFRINDQILALIGGTLAVSVGFALKDLAASFIAGITVMIDRPFQVGDRVTFEGNYGDII
TIGLRSVRMRTLNDDIITIPNNKFLNEVTTSGNYGALDMQVVIPFYVGMNEDITLARDLIQEAASSSRYIHLPKPVTVLV
KQTITDNYLAIQLTCKAYVVDTAYEKLFETDITLRVMKEFKKHNINPPKISVAAH

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1786670, Length=148, Percent_Identity=24.3243243243243, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 32990; Mature: 32990

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFILLFVGLASAVSFPTFATEELANVESISKIASLVRWSGVFFSMIVIAAMWLLLKF
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INSLVTSFGSQFVQYRMLLQKLQSFTQFFIYVSTGLIVFMMSFRINDQILALIGGTLAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VGFALKDLAASFIAGITVMIDRPFQVGDRVTFEGNYGDIITIGLRSVRMRTLNDDIITIP
HHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCEEEEEHHHHHHEECCCCEEECC
NNKFLNEVTTSGNYGALDMQVVIPFYVGMNEDITLARDLIQEAASSSRYIHLPKPVTVLV
CCHHHHHHCCCCCCCEEEHEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEECCCCHHHHH
KQTITDNYLAIQLTCKAYVVDTAYEKLFETDITLRVMKEFKKHNINPPKISVAAH
HHHHCCCEEEEEEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECC
>Mature Secondary Structure
MKKLFILLFVGLASAVSFPTFATEELANVESISKIASLVRWSGVFFSMIVIAAMWLLLKF
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INSLVTSFGSQFVQYRMLLQKLQSFTQFFIYVSTGLIVFMMSFRINDQILALIGGTLAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VGFALKDLAASFIAGITVMIDRPFQVGDRVTFEGNYGDIITIGLRSVRMRTLNDDIITIP
HHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCEEEEEHHHHHHEECCCCEEECC
NNKFLNEVTTSGNYGALDMQVVIPFYVGMNEDITLARDLIQEAASSSRYIHLPKPVTVLV
CCHHHHHHCCCCCCCEEEHEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEECCCCHHHHH
KQTITDNYLAIQLTCKAYVVDTAYEKLFETDITLRVMKEFKKHNINPPKISVAAH
HHHHCCCEEEEEEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]