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The map label for this gene is hflX [H]

Identifier: 218708880

GI number: 218708880

Start: 904978

End: 906345

Strand: Direct

Name: hflX [H]

Synonym: VS_0880

Alternate gene names: 218708880

Gene position: 904978-906345 (Clockwise)

Preceding gene: 218708879

Following gene: 218708884

Centisome position: 27.43

GC content: 45.91

Gene sequence:

>1368_bases
ATGAAACTAACAGCAAAACCAGCGGCGAATAACGCTTTACTTATTTCTATTACGACACCGGATTTTAAAGGTGACGAAGC
AAAAGAGTCTCTTGCCGAACTTGCTCGCTTAGTGACAACCCTAGGGTTTAAAGTAGTCGGTACGCAATCGCAACACCACA
GTTCATCTCAAAGACAGAACGTGTTGGGTGCCGGTAAGCTTGCTGAAATTGCACACCTAACTGGTTATCAAGGCTCTATT
GAAGAAGCTGAAGATGAAGACTTTCTTGATGAGTCGGGTTTGTTTGATTCTGAAATCGATGAGCTAGATTTTGATGATCT
TCCAACGGGCAACTTCCAATACGGTGCCGCTGATGTTGTGGTATTTGACTGTGATTTAAGTCCATCTCAAATGCGTACTG
TTGAGGCGAGTTTGGGTGTGGAAGTATTTGACCGTACTGGCATCATCATCGAAATCTTCAGCCGTCACGCTCGTACTCGT
ACTGCTCGTCTGCAAGTTGATATCGCTCGTCTAAACTACTTAGTGCCACGACTTCGTGAAACTGCTGAGGGTGATAAAGA
GCGTCAAATGGGTCAGGGCGCCGGTGAAACTTCACTAGAGCTAGACCGTCGTAACGTACGTGACCAAATTGCTGCGCTTA
AGCGTGAGCTAGTAAGCGTACAAGATGAAATGAAGACCCGACGCACAAGGCGCGCGGAGCTTTTCACTGTTGCTTTAGTT
GGCTACACCAATGCCGGTAAGTCTTCGATGATGCGTGCAATGACCGCAACCGAAGTGGTGGGTGAAGATAAACTGTTCGC
AACGCTAGATACGACGGTTCGTGCACTTCAGCCGATTACTCAGCCACGTATCTTGGTTTCAGACACCGTTGGTTTCATCA
AGAAACTGCCACACGATCTGGTTGCTTCATTCCACTCAACGCTAGCAGAAGCGCATGATGCTTCACTGCTTTTGTATGTG
GTTGATGCTTCTGACGTTTCGTTCCGCGCACAACTTGATGTGGTACACGACGTATTAGCACAAGTGGGTGTTGAAGGCAG
CGAAAAACTATTAGTGCTGAATAAGTGCGATAGATTGACTGAAGAACAGCAATTAGAGCTGATCGAAGAATTCCCAGATG
CGATGCTAACGTCGACTCGTGATCCGCTAGATATTACGAAACTGCACAAGTACATCGTTGGTGTTGCTGAAGAAGGCATG
ATCGAAGAAGAGATCACTATCCCTTATTCTGGACAAGGCATCATCGGCGAGATTCGCTCAAACATGAGTGTGGTTAAAGA
AGAGTACGATTACGAGTGTATTAAGTTGACTGTTCGCTCTAGTGAAATTGATTTAGCTCGACTGAAAAAGCGTATGCAGA
ATTCTTAA

Upstream 100 bases:

>100_bases
AGTGTGATGTGGCTATATAAAGCTGACGTAGAAACGCGTAGGATCACACTACTTTAGACCAAAAACTAGGCTGCACCTTG
GTGCATAAACAGAAGAATAC

Downstream 100 bases:

>100_bases
TCTTTTATAGCGTTTATACACAAGTTAAAATACCAAAAAAGAGAGCCTAGGCTCTCTTTTTTATTGAATCGTGATAAGCA
CCGCTCGAGCTTTGCTTATC

Product: putative GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKLTAKPAANNALLISITTPDFKGDEAKESLAELARLVTTLGFKVVGTQSQHHSSSQRQNVLGAGKLAEIAHLTGYQGSI
EEAEDEDFLDESGLFDSEIDELDFDDLPTGNFQYGAADVVVFDCDLSPSQMRTVEASLGVEVFDRTGIIIEIFSRHARTR
TARLQVDIARLNYLVPRLRETAEGDKERQMGQGAGETSLELDRRNVRDQIAALKRELVSVQDEMKTRRTRRAELFTVALV
GYTNAGKSSMMRAMTATEVVGEDKLFATLDTTVRALQPITQPRILVSDTVGFIKKLPHDLVASFHSTLAEAHDASLLLYV
VDASDVSFRAQLDVVHDVLAQVGVEGSEKLLVLNKCDRLTEEQQLELIEEFPDAMLTSTRDPLDITKLHKYIVGVAEEGM
IEEEITIPYSGQGIIGEIRSNMSVVKEEYDYECIKLTVRSSEIDLARLKKRMQNS

Sequences:

>Translated_455_residues
MKLTAKPAANNALLISITTPDFKGDEAKESLAELARLVTTLGFKVVGTQSQHHSSSQRQNVLGAGKLAEIAHLTGYQGSI
EEAEDEDFLDESGLFDSEIDELDFDDLPTGNFQYGAADVVVFDCDLSPSQMRTVEASLGVEVFDRTGIIIEIFSRHARTR
TARLQVDIARLNYLVPRLRETAEGDKERQMGQGAGETSLELDRRNVRDQIAALKRELVSVQDEMKTRRTRRAELFTVALV
GYTNAGKSSMMRAMTATEVVGEDKLFATLDTTVRALQPITQPRILVSDTVGFIKKLPHDLVASFHSTLAEAHDASLLLYV
VDASDVSFRAQLDVVHDVLAQVGVEGSEKLLVLNKCDRLTEEQQLELIEEFPDAMLTSTRDPLDITKLHKYIVGVAEEGM
IEEEITIPYSGQGIIGEIRSNMSVVKEEYDYECIKLTVRSSEIDLARLKKRMQNS
>Mature_455_residues
MKLTAKPAANNALLISITTPDFKGDEAKESLAELARLVTTLGFKVVGTQSQHHSSSQRQNVLGAGKLAEIAHLTGYQGSI
EEAEDEDFLDESGLFDSEIDELDFDDLPTGNFQYGAADVVVFDCDLSPSQMRTVEASLGVEVFDRTGIIIEIFSRHARTR
TARLQVDIARLNYLVPRLRETAEGDKERQMGQGAGETSLELDRRNVRDQIAALKRELVSVQDEMKTRRTRRAELFTVALV
GYTNAGKSSMMRAMTATEVVGEDKLFATLDTTVRALQPITQPRILVSDTVGFIKKLPHDLVASFHSTLAEAHDASLLLYV
VDASDVSFRAQLDVVHDVLAQVGVEGSEKLLVLNKCDRLTEEQQLELIEEFPDAMLTSTRDPLDITKLHKYIVGVAEEGM
IEEEITIPYSGQGIIGEIRSNMSVVKEEYDYECIKLTVRSSEIDLARLKKRMQNS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=136, Percent_Identity=36.0294117647059, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI310124267, Length=136, Percent_Identity=36.0294117647059, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI310124171, Length=136, Percent_Identity=36.0294117647059, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI310124169, Length=136, Percent_Identity=36.0294117647059, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI310133116, Length=136, Percent_Identity=36.0294117647059, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310133118, Length=136, Percent_Identity=36.0294117647059, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1790615, Length=457, Percent_Identity=32.3851203501094, Blast_Score=192, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17561038, Length=244, Percent_Identity=31.9672131147541, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24650079, Length=250, Percent_Identity=32.4, Blast_Score=99, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50498; Mature: 50498

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTAKPAANNALLISITTPDFKGDEAKESLAELARLVTTLGFKVVGTQSQHHSSSQRQN
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCHHCCCHHHHH
VLGAGKLAEIAHLTGYQGSIEEAEDEDFLDESGLFDSEIDELDFDDLPTGNFQYGAADVV
HHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
VFDCDLSPSQMRTVEASLGVEVFDRTGIIIEIFSRHARTRTARLQVDIARLNYLVPRLRE
EEECCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHH
TAEGDKERQMGQGAGETSLELDRRNVRDQIAALKRELVSVQDEMKTRRTRRAELFTVALV
HHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
GYTNAGKSSMMRAMTATEVVGEDKLFATLDTTVRALQPITQPRILVSDTVGFIKKLPHDL
EECCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCHHH
VASFHSTLAEAHDASLLLYVVDASDVSFRAQLDVVHDVLAQVGVEGSEKLLVLNKCDRLT
HHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCC
EEQQLELIEEFPDAMLTSTRDPLDITKLHKYIVGVAEEGMIEEEITIPYSGQGIIGEIRS
HHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHH
NMSVVKEEYDYECIKLTVRSSEIDLARLKKRMQNS
HHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKLTAKPAANNALLISITTPDFKGDEAKESLAELARLVTTLGFKVVGTQSQHHSSSQRQN
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCHHCCCHHHHH
VLGAGKLAEIAHLTGYQGSIEEAEDEDFLDESGLFDSEIDELDFDDLPTGNFQYGAADVV
HHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
VFDCDLSPSQMRTVEASLGVEVFDRTGIIIEIFSRHARTRTARLQVDIARLNYLVPRLRE
EEECCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHH
TAEGDKERQMGQGAGETSLELDRRNVRDQIAALKRELVSVQDEMKTRRTRRAELFTVALV
HHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
GYTNAGKSSMMRAMTATEVVGEDKLFATLDTTVRALQPITQPRILVSDTVGFIKKLPHDL
EECCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCHHH
VASFHSTLAEAHDASLLLYVVDASDVSFRAQLDVVHDVLAQVGVEGSEKLLVLNKCDRLT
HHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCC
EEQQLELIEEFPDAMLTSTRDPLDITKLHKYIVGVAEEGMIEEEITIPYSGQGIIGEIRS
HHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHH
NMSVVKEEYDYECIKLTVRSSEIDLARLKKRMQNS
HHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]