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The map label for this gene is secD [H]

Identifier: 218708623

GI number: 218708623

Start: 625017

End: 626873

Strand: Direct

Name: secD [H]

Synonym: VS_0601

Alternate gene names: 218708623

Gene position: 625017-626873 (Clockwise)

Preceding gene: 218708622

Following gene: 218708624

Centisome position: 18.94

GC content: 46.31

Gene sequence:

>1857_bases
GTGCTAAACCGTTATCCGTTATGGAAGTATTTGATGGTGATGTTTGCCATCGCTATCGCTGCGTTGTACGCACTTCCAAA
TATATACGGTGAAGATCCGGCAGTTCAAGTTACAGGGGCGCGTGGCGCCTCTGTAGATCTGTCTACGCTGGATGCTGTCA
CCAATGCTCTTGAAGCAGAAAACCTTTCTACTAAATCCGTTGCTCTCGAAAACGGTTCCATTCTTGTTCGATTTAACGAT
ACAGATACGCAAATCAGTGCCCGTGATATCATCACAGAAGCACTCGGTGATGACGTTATCGTAGCTTTAAACCTAGCGGC
TTCAACTCCTGATTGGCTTGAATCTATTGGTGCTGCACCAATGAAACTGGGTCTTGATCTACGTGGTGGTGTTCACTTCT
TAATGGAAGTGGATATGGACGCTGCGATGCAAAAACTGGTTGGCCAACAAGAAGAAGCGTTCCGCAGTGAACTTCGTGAA
GAGAAAATCCGCTACCGTGCTATTCGCCCATCGGGTAAAGATGCGGTTGAAGTGATTCTGCGTAACGAAGAGCAGCTTGC
TGAAGCGAAATCGCTACTGCAATCTAAGCACCAAGATATGACGTTCGTAGATTCAGAATCTAACGGTCGTTTCTCTTTGA
TTGCTAACTTCACTGAAACTCGTCTTCAAGAAATCCGCAATTATGCGGTAGAGCAAAACATTACTATTCTACGTAACCGT
GTTAACGAACTCGGTGTTGCTGAGCCTTTGGTTCAACGTCAAGGTGCTAGCCGTATCGTAGTGGAATTGCCAGGTGTTCA
AGACACGGCTCGTGCTAAAGAAATTTTAGGCGCAACCGCGACTCTTGAATTCCGTGAAGTGGACAGCAGTGCCGATTTGG
CTGCTGCAGCTTCTGGCCGTGCTCCTGCTGGTAGTGAAATTAAGCAAGACCGTGATGGTCGTCCTGTAGTACTTAAGAAA
CGCGTTATCTTAGGCGGTTCTAGCATTACAGATGCAAGCTCAAGTGTTGATGAATATGGTCGCCCACAAGTTAACATCTC
GCTAGACAGCGAAGGTGGTAGCAAGATGTCTACATTCTCTCGTCAAAATATCGGTAAGCTAATGGCAACCGTATTTGCAG
AGTATAAAGACAGCGGTCGTAAAACACCTGAAGGCCGAGTGATCCTAAGTAAGCACGAAGAAGTGATTAACCAAGCGACG
ATTCAATCTGCGCTTGGCCGTAACTTCCGTATTACAGGTATCGACTCAACGGCTGAAGCTCATAACTTGGCACTTCTACT
ACGTGCAGGTGCATTGATTGCGCCTATCTCGATTGTAGAAGAGCGTACGATTGGTCCATCTATGGGTCAACAAAACATCG
ATATGGGTATCATGGCGATGGTTTGGGGTATGGCTGCAGTAATGCTGTTTACACTGCTTTACTACCGTACTTTCGGTTTG
ATTGCGAACGTCGCTCTGATGGCTAACTTAGTGTTGATTATTGGTGTGATGTCGATGATTCCTGGCGCGACAATGACGCT
ACCAGGCATTGCCGGTATCGTATTGACGGTCGGTATGGCAGTCGATGCCAACGTTCTTATCTTTGAGCGTATACGTGAAG
AACTTCGAGATGGACGCAGTCCACAACAAGCGATTCACCAAGGTTATGCAAACGCATTTAGTACAATCGCCGATGCCAAC
ATCACCACACTACTAACAGCAATCATTCTATTTGCTGTCGGTACAGGTGCGATTAAAGGCTTCGCGGTAACGTTATCAAT
CGGTATCTTGACTTCAATGTTTACAGCTATTATCGGAACACGTTGTATCGTGAACCTGATGTATGGCGGCAAACGCGTTA
AGAAACTGTCGATCTAA

Upstream 100 bases:

>100_bases
TGAACGCAAACAACGAAGTCGTTATCAAGAAAGACTTCGTTACAGCAGTGCTACCAAAAGGTACTCTGAAATCACTATAA
ACAGCTAGAGGATCCTCGCT

Downstream 100 bases:

>100_bases
GGCTAGGAATTAATATGTTTCAGATTCTAAAAGCAGACAAAATGATCGACTTCATGCGTTGGTCAAAGGTTGCCTTTTTA
TTCTCAATCTTGATGATTGG

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MLNRYPLWKYLMVMFAIAIAALYALPNIYGEDPAVQVTGARGASVDLSTLDAVTNALEAENLSTKSVALENGSILVRFND
TDTQISARDIITEALGDDVIVALNLAASTPDWLESIGAAPMKLGLDLRGGVHFLMEVDMDAAMQKLVGQQEEAFRSELRE
EKIRYRAIRPSGKDAVEVILRNEEQLAEAKSLLQSKHQDMTFVDSESNGRFSLIANFTETRLQEIRNYAVEQNITILRNR
VNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDSSADLAAAASGRAPAGSEIKQDRDGRPVVLKK
RVILGGSSITDASSSVDEYGRPQVNISLDSEGGSKMSTFSRQNIGKLMATVFAEYKDSGRKTPEGRVILSKHEEVINQAT
IQSALGRNFRITGIDSTAEAHNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIMAMVWGMAAVMLFTLLYYRTFGL
IANVALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRSPQQAIHQGYANAFSTIADAN
ITTLLTAIILFAVGTGAIKGFAVTLSIGILTSMFTAIIGTRCIVNLMYGGKRVKKLSI

Sequences:

>Translated_618_residues
MLNRYPLWKYLMVMFAIAIAALYALPNIYGEDPAVQVTGARGASVDLSTLDAVTNALEAENLSTKSVALENGSILVRFND
TDTQISARDIITEALGDDVIVALNLAASTPDWLESIGAAPMKLGLDLRGGVHFLMEVDMDAAMQKLVGQQEEAFRSELRE
EKIRYRAIRPSGKDAVEVILRNEEQLAEAKSLLQSKHQDMTFVDSESNGRFSLIANFTETRLQEIRNYAVEQNITILRNR
VNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDSSADLAAAASGRAPAGSEIKQDRDGRPVVLKK
RVILGGSSITDASSSVDEYGRPQVNISLDSEGGSKMSTFSRQNIGKLMATVFAEYKDSGRKTPEGRVILSKHEEVINQAT
IQSALGRNFRITGIDSTAEAHNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIMAMVWGMAAVMLFTLLYYRTFGL
IANVALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRSPQQAIHQGYANAFSTIADAN
ITTLLTAIILFAVGTGAIKGFAVTLSIGILTSMFTAIIGTRCIVNLMYGGKRVKKLSI
>Mature_618_residues
MLNRYPLWKYLMVMFAIAIAALYALPNIYGEDPAVQVTGARGASVDLSTLDAVTNALEAENLSTKSVALENGSILVRFND
TDTQISARDIITEALGDDVIVALNLAASTPDWLESIGAAPMKLGLDLRGGVHFLMEVDMDAAMQKLVGQQEEAFRSELRE
EKIRYRAIRPSGKDAVEVILRNEEQLAEAKSLLQSKHQDMTFVDSESNGRFSLIANFTETRLQEIRNYAVEQNITILRNR
VNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDSSADLAAAASGRAPAGSEIKQDRDGRPVVLKK
RVILGGSSITDASSSVDEYGRPQVNISLDSEGGSKMSTFSRQNIGKLMATVFAEYKDSGRKTPEGRVILSKHEEVINQAT
IQSALGRNFRITGIDSTAEAHNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIMAMVWGMAAVMLFTLLYYRTFGL
IANVALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRSPQQAIHQGYANAFSTIADAN
ITTLLTAIILFAVGTGAIKGFAVTLSIGILTSMFTAIIGTRCIVNLMYGGKRVKKLSI

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=618, Percent_Identity=62.621359223301, Blast_Score=781, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 66724; Mature: 66724

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRYPLWKYLMVMFAIAIAALYALPNIYGEDPAVQVTGARGASVDLSTLDAVTNALEAE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHC
NLSTKSVALENGSILVRFNDTDTQISARDIITEALGDDVIVALNLAASTPDWLESIGAAP
CCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCC
MKLGLDLRGGVHFLMEVDMDAAMQKLVGQQEEAFRSELREEKIRYRAIRPSGKDAVEVIL
HHCCCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHH
RNEEQLAEAKSLLQSKHQDMTFVDSESNGRFSLIANFTETRLQEIRNYAVEQNITILRNR
CCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECHHHHHHHHHHHHHHHCCHHHHHHH
VNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDSSADLAAAASGR
HHHCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHEEEEEECCCCCCHHHHCCCC
APAGSEIKQDRDGRPVVLKKRVILGGSSITDASSSVDEYGRPQVNISLDSEGGSKMSTFS
CCCCCHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHH
RQNIGKLMATVFAEYKDSGRKTPEGRVILSKHEEVINQATIQSALGRNFRITGIDSTAEA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCHH
HNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIMAMVWGMAAVMLFTLLYYRTFGL
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IANVALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRS
HHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
PQQAIHQGYANAFSTIADANITTLLTAIILFAVGTGAIKGFAVTLSIGILTSMFTAIIGT
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
RCIVNLMYGGKRVKKLSI
HHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MLNRYPLWKYLMVMFAIAIAALYALPNIYGEDPAVQVTGARGASVDLSTLDAVTNALEAE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHC
NLSTKSVALENGSILVRFNDTDTQISARDIITEALGDDVIVALNLAASTPDWLESIGAAP
CCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCC
MKLGLDLRGGVHFLMEVDMDAAMQKLVGQQEEAFRSELREEKIRYRAIRPSGKDAVEVIL
HHCCCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHH
RNEEQLAEAKSLLQSKHQDMTFVDSESNGRFSLIANFTETRLQEIRNYAVEQNITILRNR
CCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECHHHHHHHHHHHHHHHCCHHHHHHH
VNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDSSADLAAAASGR
HHHCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHEEEEEECCCCCCHHHHCCCC
APAGSEIKQDRDGRPVVLKKRVILGGSSITDASSSVDEYGRPQVNISLDSEGGSKMSTFS
CCCCCHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHH
RQNIGKLMATVFAEYKDSGRKTPEGRVILSKHEEVINQATIQSALGRNFRITGIDSTAEA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCHH
HNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIMAMVWGMAAVMLFTLLYYRTFGL
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IANVALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRS
HHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
PQQAIHQGYANAFSTIADANITTLLTAIILFAVGTGAIKGFAVTLSIGILTSMFTAIIGT
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
RCIVNLMYGGKRVKKLSI
HHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]