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The map label for this gene is ybhA [H]

Identifier: 218708236

GI number: 218708236

Start: 170505

End: 171377

Strand: Reverse

Name: ybhA [H]

Synonym: VS_0173

Alternate gene names: 218708236

Gene position: 171377-170505 (Counterclockwise)

Preceding gene: 218708239

Following gene: 218708235

Centisome position: 5.19

GC content: 42.61

Gene sequence:

>873_bases
TTGCGTCATGAGAAGTCACTGGAGAGTAAAATGAAATACCAAGCAGTAATGATTGATTTAGATGGAACACTGTTAAGTGA
TGCTGAGCAGATCTGCGTGACTAACAAACAAGCGATTTGTCTTGCCGTTAATAATGGATATCAGGTGAGCTTGGCGAGTG
GTAGACCGCACCAGCTGATGATGCCATATGTTGACCAGCTTCAATTATCGCTACCAATCATCTGCTGCAATGGTGCCTAT
ATTTATGACCCTAAAACACAACGTGTTCAACATCAGCACACAATTAGTCATGAATCACTAACGGGTCTGTTGAGCTTACT
GAATGATGGACATTTCACCTTCACCATCTATTCAAGTAAAGGCATCTTTGCTCAAAAAGAATCAACTCATACAAAGGGTT
TAGAAAAAAAGGCTGAGGTTATTAATGCCGCAATGGAGCTGCAGATTATCCCAACGCTGACCGAACTCATCGCTCGCAGT
GGCGATGTATACAAAGTATTAGTGTCTAGCCAAGACAAAGAATCTCTAAACCAGTTACGAGATTCCTTAAAAATGCACTT
CCAAGCTGACTTATCAACACCGAATAAATTGGACATTACGTCTAAAGCAGCCACCAAAGGCCACGCTCTTCAGCAGTGGC
TAAATGACCAAAGAATTTCATCTCATAACACCATTGCTTTTGGGGATGGGGACAACGATGCCTCTATGTTCCGACTTGTC
GGAGAACCTGTCGCAATGGCTAATGCCAGCCCTGCTTTAAAAGGCATGGCTAATCTAATTGTTACCAATAACAACGGCTG
TGGAATTGGCCAGTACCTTCGCTTGATAGTGCAAGAAGGCCAACACACATGCCAAAACACTTTTAGTTACTAA

Upstream 100 bases:

>100_bases
TGAATTAATTTGACTCAAAATGTGTGATCGAAACCATTATTTCGTTCATAATAAATCAAAAATGACTTTACGTGACCGTA
CTTGACCACTTATAGTCACT

Downstream 100 bases:

>100_bases
GGATAAATCATGAAAAAAGTAAAAATTGCCGCAGGATTAGCACACGTAGATTACGGCCACATTGCAGACGTAGTGAAAGA
AGTATCTGATGCTGGTGCCG

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MRHEKSLESKMKYQAVMIDLDGTLLSDAEQICVTNKQAICLAVNNGYQVSLASGRPHQLMMPYVDQLQLSLPIICCNGAY
IYDPKTQRVQHQHTISHESLTGLLSLLNDGHFTFTIYSSKGIFAQKESTHTKGLEKKAEVINAAMELQIIPTLTELIARS
GDVYKVLVSSQDKESLNQLRDSLKMHFQADLSTPNKLDITSKAATKGHALQQWLNDQRISSHNTIAFGDGDNDASMFRLV
GEPVAMANASPALKGMANLIVTNNNGCGIGQYLRLIVQEGQHTCQNTFSY

Sequences:

>Translated_290_residues
MRHEKSLESKMKYQAVMIDLDGTLLSDAEQICVTNKQAICLAVNNGYQVSLASGRPHQLMMPYVDQLQLSLPIICCNGAY
IYDPKTQRVQHQHTISHESLTGLLSLLNDGHFTFTIYSSKGIFAQKESTHTKGLEKKAEVINAAMELQIIPTLTELIARS
GDVYKVLVSSQDKESLNQLRDSLKMHFQADLSTPNKLDITSKAATKGHALQQWLNDQRISSHNTIAFGDGDNDASMFRLV
GEPVAMANASPALKGMANLIVTNNNGCGIGQYLRLIVQEGQHTCQNTFSY
>Mature_290_residues
MRHEKSLESKMKYQAVMIDLDGTLLSDAEQICVTNKQAICLAVNNGYQVSLASGRPHQLMMPYVDQLQLSLPIICCNGAY
IYDPKTQRVQHQHTISHESLTGLLSLLNDGHFTFTIYSSKGIFAQKESTHTKGLEKKAEVINAAMELQIIPTLTELIARS
GDVYKVLVSSQDKESLNQLRDSLKMHFQADLSTPNKLDITSKAATKGHALQQWLNDQRISSHNTIAFGDGDNDASMFRLV
GEPVAMANASPALKGMANLIVTNNNGCGIGQYLRLIVQEGQHTCQNTFSY

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates pyridoxalphosphate and erythrose 4-phosphate [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI1786982, Length=267, Percent_Identity=27.3408239700375, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI48994981, Length=269, Percent_Identity=27.1375464684015, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006380 [H]

Pfam domain/function: PF00702 Hydrolase; PF05116 S6PP [H]

EC number: NA

Molecular weight: Translated: 32042; Mature: 32042

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHEKSLESKMKYQAVMIDLDGTLLSDAEQICVTNKQAICLAVNNGYQVSLASGRPHQLM
CCCHHHHHHHHEEEEEEEEECCCHHHCCHHHHCCCCCEEEEEECCCEEEEECCCCCCEEE
MPYVDQLQLSLPIICCNGAYIYDPKTQRVQHQHTISHESLTGLLSLLNDGHFTFTIYSSK
CCHHHHHHEECCEEEECCEEEECCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECC
GIFAQKESTHTKGLEKKAEVINAAMELQIIPTLTELIARSGDVYKVLVSSQDKESLNQLR
CCEECCCCCHHHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
DSLKMHFQADLSTPNKLDITSKAATKGHALQQWLNDQRISSHNTIAFGDGDNDASMFRLV
HHHHEEEEECCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHH
GEPVAMANASPALKGMANLIVTNNNGCGIGQYLRLIVQEGQHTCQNTFSY
CCCHHHCCCCHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure
MRHEKSLESKMKYQAVMIDLDGTLLSDAEQICVTNKQAICLAVNNGYQVSLASGRPHQLM
CCCHHHHHHHHEEEEEEEEECCCHHHCCHHHHCCCCCEEEEEECCCEEEEECCCCCCEEE
MPYVDQLQLSLPIICCNGAYIYDPKTQRVQHQHTISHESLTGLLSLLNDGHFTFTIYSSK
CCHHHHHHEECCEEEECCEEEECCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECC
GIFAQKESTHTKGLEKKAEVINAAMELQIIPTLTELIARSGDVYKVLVSSQDKESLNQLR
CCEECCCCCHHHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
DSLKMHFQADLSTPNKLDITSKAATKGHALQQWLNDQRISSHNTIAFGDGDNDASMFRLV
HHHHEEEEECCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHH
GEPVAMANASPALKGMANLIVTNNNGCGIGQYLRLIVQEGQHTCQNTFSY
CCCHHHCCCCHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665460; 8564363; 8905232; 9278503 [H]