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The map label for this gene is cysQ [H]

Identifier: 218708210

GI number: 218708210

Start: 140080

End: 140907

Strand: Reverse

Name: cysQ [H]

Synonym: VS_0146

Alternate gene names: 218708210

Gene position: 140907-140080 (Counterclockwise)

Preceding gene: 218708211

Following gene: 218708197

Centisome position: 4.27

GC content: 47.95

Gene sequence:

>828_bases
ATGCCAATAACAAAAGATTTGTCTCACCTGCTGCCCTCTGTCATTGAGATTGCTCGCTCTGCTGGGCAACTGATCTTAGA
GATCTACGAGAAAAAAGATTACGAAGAGTTTACCAAGAGTGATGATACGCCCGTCACTAGTGCTGATCTCGCCGCTCATA
AACTGATCTCGAAAAAACTTAGCGAACTGACACCTGATATTCCGGTGTTATCGGAAGAAGCCGCTGATATCAGCCTAGAG
CAACGTTCTCAATGGGATCGCTACTGGTTGGTTGACCCGCTGGACGGTACACAGGAGTTCATCGCACGAAGTGGCGATTT
CGCGACAATCATAGCCCTAATCGAACACAACAAGCCGGTAATGGGCGTCGTGTACGCACCGGTTTCAGGTGTGAGTTATT
ACGCTTACAGTGGTAAAGGTGCATGGAAAATTCCAGACCTTAATGACAGCGTTAAAATCAAAACGCACCGTCACGAGCTA
CCAAACCAATCGATCACGATGGCAATCAGCCGTCGCCAAGACATCAATCGAATCACTAACCGTATGAGCTCTGCTTGGAA
CTACGACTTAGTTCCTCTTGGCTCTGCTGCGCTTAAGGCATGTTTAGTCGCAGAAGGTACTGTGGACTGTTATCTACGTA
TTGGACCAACCGGAGAGTGGGATACCGCAGCAACCCAGTGCATTGTTGAAGAAGCTGGCGGACGAATCTTAAGTACCCAG
TTAGAGCCGCTTTCGTACAATGAAAGAGAGACGCTTGAGAACCCGAACTTCATTGTGCTTGGTGATGCTGACTTACCGTG
GGCAGAAATCTTACAAGGTAAAGACTAG

Upstream 100 bases:

>100_bases
CTTCTGTGAGGCTCGCAGTATTACCGCCCTACTATTAGCCCTTCGCGTATTAAACAATAATTAAAACAGTCAGAATCACT
CGAAGAGTAAGAGAATATTT

Downstream 100 bases:

>100_bases
GCTTACTTGCTCTCTTTAACCGTCAGATATCCTCTAGATTCTCAGAAAAAATAAAACGGGCACCTCACTGAGGTGCCCGT
TTTATTTATATTTCGTCGTT

Product: hypothetical protein

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MPITKDLSHLLPSVIEIARSAGQLILEIYEKKDYEEFTKSDDTPVTSADLAAHKLISKKLSELTPDIPVLSEEAADISLE
QRSQWDRYWLVDPLDGTQEFIARSGDFATIIALIEHNKPVMGVVYAPVSGVSYYAYSGKGAWKIPDLNDSVKIKTHRHEL
PNQSITMAISRRQDINRITNRMSSAWNYDLVPLGSAALKACLVAEGTVDCYLRIGPTGEWDTAATQCIVEEAGGRILSTQ
LEPLSYNERETLENPNFIVLGDADLPWAEILQGKD

Sequences:

>Translated_275_residues
MPITKDLSHLLPSVIEIARSAGQLILEIYEKKDYEEFTKSDDTPVTSADLAAHKLISKKLSELTPDIPVLSEEAADISLE
QRSQWDRYWLVDPLDGTQEFIARSGDFATIIALIEHNKPVMGVVYAPVSGVSYYAYSGKGAWKIPDLNDSVKIKTHRHEL
PNQSITMAISRRQDINRITNRMSSAWNYDLVPLGSAALKACLVAEGTVDCYLRIGPTGEWDTAATQCIVEEAGGRILSTQ
LEPLSYNERETLENPNFIVLGDADLPWAEILQGKD
>Mature_274_residues
PITKDLSHLLPSVIEIARSAGQLILEIYEKKDYEEFTKSDDTPVTSADLAAHKLISKKLSELTPDIPVLSEEAADISLEQ
RSQWDRYWLVDPLDGTQEFIARSGDFATIIALIEHNKPVMGVVYAPVSGVSYYAYSGKGAWKIPDLNDSVKIKTHRHELP
NQSITMAISRRQDINRITNRMSSAWNYDLVPLGSAALKACLVAEGTVDCYLRIGPTGEWDTAATQCIVEEAGGRILSTQL
EPLSYNERETLENPNFIVLGDADLPWAEILQGKD

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=254, Percent_Identity=27.1653543307087, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI221625487, Length=254, Percent_Identity=27.1653543307087, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI7657236, Length=241, Percent_Identity=26.9709543568465, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790659, Length=252, Percent_Identity=43.6507936507937, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1788882, Length=230, Percent_Identity=31.304347826087, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193202572, Length=262, Percent_Identity=26.3358778625954, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193202570, Length=267, Percent_Identity=27.3408239700375, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71995905, Length=288, Percent_Identity=22.5694444444444, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=288, Percent_Identity=22.5694444444444, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320493, Length=254, Percent_Identity=29.9212598425197, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6321836, Length=223, Percent_Identity=27.8026905829596, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24664922, Length=230, Percent_Identity=28.695652173913, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24664926, Length=231, Percent_Identity=27.7056277056277, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641722, Length=277, Percent_Identity=21.2996389891697, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 30548; Mature: 30417

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITKDLSHLLPSVIEIARSAGQLILEIYEKKDYEEFTKSDDTPVTSADLAAHKLISKKL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHH
SELTPDIPVLSEEAADISLEQRSQWDRYWLVDPLDGTQEFIARSGDFATIIALIEHNKPV
HHHCCCCCCCCCHHHCCCHHHHCCCCCEEEECCCCCHHHHHHCCCCCEEEEEEECCCCCE
MGVVYAPVSGVSYYAYSGKGAWKIPDLNDSVKIKTHRHELPNQSITMAISRRQDINRITN
EEEEECCCCCCEEEEECCCCCEECCCCCCCEEEEEHHHHCCCCCEEEEEHHHHHHHHHHH
RMSSAWNYDLVPLGSAALKACLVAEGTVDCYLRIGPTGEWDTAATQCIVEEAGGRILSTQ
HHHHCCCCCEEECCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEE
LEPLSYNERETLENPNFIVLGDADLPWAEILQGKD
CCCCCCCCHHHCCCCCEEEEECCCCCHHHHHCCCC
>Mature Secondary Structure 
PITKDLSHLLPSVIEIARSAGQLILEIYEKKDYEEFTKSDDTPVTSADLAAHKLISKKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHH
SELTPDIPVLSEEAADISLEQRSQWDRYWLVDPLDGTQEFIARSGDFATIIALIEHNKPV
HHHCCCCCCCCCHHHCCCHHHHCCCCCEEEECCCCCHHHHHHCCCCCEEEEEEECCCCCE
MGVVYAPVSGVSYYAYSGKGAWKIPDLNDSVKIKTHRHELPNQSITMAISRRQDINRITN
EEEEECCCCCCEEEEECCCCCEECCCCCCCEEEEEHHHHCCCCCEEEEEHHHHHHHHHHH
RMSSAWNYDLVPLGSAALKACLVAEGTVDCYLRIGPTGEWDTAATQCIVEEAGGRILSTQ
HHHHCCCCCEEECCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEE
LEPLSYNERETLENPNFIVLGDADLPWAEILQGKD
CCCCCCCCHHHCCCCCEEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]