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The map label for this gene is dppC [H]

Identifier: 218708143

GI number: 218708143

Start: 67238

End: 68176

Strand: Direct

Name: dppC [H]

Synonym: VS_0077

Alternate gene names: 218708143

Gene position: 67238-68176 (Clockwise)

Preceding gene: 218708142

Following gene: 218708144

Centisome position: 2.04

GC content: 46.33

Gene sequence:

>939_bases
ATGGAACAGACATCGACAGTGCCGTCTCGCTGGGAACGTTTTAAGCAATCAGACATTGTGTATTACTTCTTACGCGACAA
AGTGGCAATGGTGAGTTTCGCCATTTTCTCAATCTTTTTAGTGATGGCACTAGCTGCCCCTATTCTAGCGCCAACAGACC
CGTACGACGTGACATCGATTGATATCATGGACTCAGAGCTGCCACCATCATGGATGGAAGACGGCGAAGAACGTTTCTTG
TTAGGAACGGATGAGCAAGGCCGTGATATTTTATCGACTATGCTTTACGGTTCTCGTTTATCACTGACTATTGGTTTCTT
AGCGGTAGGTCTACAACTGACGCTTGGTATTATCATTGGCTTGTCTGCGGGTTACTTCGGTGGCCGTATTGATAGCTTCT
TGATGCGCTTCGCTGATGTTCAGCTTTCGTTCTCAACCATGATGGTTGCGATCATTGTCTCGGCCATCTTTAAGGCAAGT
TTCGGTAGTGATTTCTATGCACAATACGCTGTGGTGATGCTGGTGGTGATCATTGGTATCGCAGAATGGCCGCAGTATGC
GCGTACTATTCGTGCATCAGTATTAGCAGAGAAGAAGAAAGAGTACGTAGAAGCGGCACGTGTGATGGGCTTTAGAGCAC
CTCGTATCATGTTCCGTCATATTCTGCCTAACTGTTTATCACCGATTTTGGTTATCTCTACAGTACAGGTGGCAAATGCC
ATCATGTCAGAAGCGGCACTTTCTTTCCTAGGTTTAGGCCTTCCAGTCGACCAACCGTCACTGGGTGCTCTGATTAGTAC
TGGTTTTAACTACATCTTCTCAGGAGCATGGTGGATCACTGCATTCCCAGGTGTGCTTTTGGTGACATTGGTTCTAGTTA
TCAACCTACTAGGCGACTGGTTACGTGACGTGTTTAACCCGAAAATCTATAAAGGGTGA

Upstream 100 bases:

>100_bases
TTTTTGTTGGTCTTATTTTCGTCGTGACTAACACAATTGTTGATTTGCTTTACGGTGTTATCAACCCAACCGTTAACATC
ACAGGGAAAGGAGCATAATC

Downstream 100 bases:

>100_bases
TAGTTCAGTTTGATTTTTAGTAAAAAAAATCACTAAACTAAGAGTCGTAAGCAATTACGGCTCTTTTTTTGCTTAATGAA
TTTGGAACTTAGTACCATTG

Product: dipeptide transport system permease dppC

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MEQTSTVPSRWERFKQSDIVYYFLRDKVAMVSFAIFSIFLVMALAAPILAPTDPYDVTSIDIMDSELPPSWMEDGEERFL
LGTDEQGRDILSTMLYGSRLSLTIGFLAVGLQLTLGIIIGLSAGYFGGRIDSFLMRFADVQLSFSTMMVAIIVSAIFKAS
FGSDFYAQYAVVMLVVIIGIAEWPQYARTIRASVLAEKKKEYVEAARVMGFRAPRIMFRHILPNCLSPILVISTVQVANA
IMSEAALSFLGLGLPVDQPSLGALISTGFNYIFSGAWWITAFPGVLLVTLVLVINLLGDWLRDVFNPKIYKG

Sequences:

>Translated_312_residues
MEQTSTVPSRWERFKQSDIVYYFLRDKVAMVSFAIFSIFLVMALAAPILAPTDPYDVTSIDIMDSELPPSWMEDGEERFL
LGTDEQGRDILSTMLYGSRLSLTIGFLAVGLQLTLGIIIGLSAGYFGGRIDSFLMRFADVQLSFSTMMVAIIVSAIFKAS
FGSDFYAQYAVVMLVVIIGIAEWPQYARTIRASVLAEKKKEYVEAARVMGFRAPRIMFRHILPNCLSPILVISTVQVANA
IMSEAALSFLGLGLPVDQPSLGALISTGFNYIFSGAWWITAFPGVLLVTLVLVINLLGDWLRDVFNPKIYKG
>Mature_312_residues
MEQTSTVPSRWERFKQSDIVYYFLRDKVAMVSFAIFSIFLVMALAAPILAPTDPYDVTSIDIMDSELPPSWMEDGEERFL
LGTDEQGRDILSTMLYGSRLSLTIGFLAVGLQLTLGIIIGLSAGYFGGRIDSFLMRFADVQLSFSTMMVAIIVSAIFKAS
FGSDFYAQYAVVMLVVIIGIAEWPQYARTIRASVLAEKKKEYVEAARVMGFRAPRIMFRHILPNCLSPILVISTVQVANA
IMSEAALSFLGLGLPVDQPSLGALISTGFNYIFSGAWWITAFPGVLLVTLVLVINLLGDWLRDVFNPKIYKG

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=292, Percent_Identity=41.0958904109589, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1787760, Length=310, Percent_Identity=33.2258064516129, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1787054, Length=299, Percent_Identity=32.7759197324415, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787498, Length=291, Percent_Identity=32.9896907216495, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789889, Length=257, Percent_Identity=31.1284046692607, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788505, Length=254, Percent_Identity=29.5275590551181, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787549, Length=249, Percent_Identity=31.7269076305221, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34552; Mature: 34552

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTSTVPSRWERFKQSDIVYYFLRDKVAMVSFAIFSIFLVMALAAPILAPTDPYDVTSI
CCCCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
DIMDSELPPSWMEDGEERFLLGTDEQGRDILSTMLYGSRLSLTIGFLAVGLQLTLGIIIG
EEECCCCCCHHHCCCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LSAGYFGGRIDSFLMRFADVQLSFSTMMVAIIVSAIFKASFGSDFYAQYAVVMLVVIIGI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AEWPQYARTIRASVLAEKKKEYVEAARVMGFRAPRIMFRHILPNCLSPILVISTVQVANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMSEAALSFLGLGLPVDQPSLGALISTGFNYIFSGAWWITAFPGVLLVTLVLVINLLGDW
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LRDVFNPKIYKG
HHHHCCCCCCCC
>Mature Secondary Structure
MEQTSTVPSRWERFKQSDIVYYFLRDKVAMVSFAIFSIFLVMALAAPILAPTDPYDVTSI
CCCCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
DIMDSELPPSWMEDGEERFLLGTDEQGRDILSTMLYGSRLSLTIGFLAVGLQLTLGIIIG
EEECCCCCCHHHCCCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LSAGYFGGRIDSFLMRFADVQLSFSTMMVAIIVSAIFKASFGSDFYAQYAVVMLVVIIGI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AEWPQYARTIRASVLAEKKKEYVEAARVMGFRAPRIMFRHILPNCLSPILVISTVQVANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMSEAALSFLGLGLPVDQPSLGALISTGFNYIFSGAWWITAFPGVLLVTLVLVINLLGDW
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LRDVFNPKIYKG
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]