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The map label for this gene is trkH [H]

Identifier: 218708130

GI number: 218708130

Start: 41748

End: 43205

Strand: Direct

Name: trkH [H]

Synonym: VS_0043

Alternate gene names: 218708130

Gene position: 41748-43205 (Clockwise)

Preceding gene: 218708129

Following gene: 218708131

Centisome position: 1.27

GC content: 45.2

Gene sequence:

>1458_bases
ATGCAATTTCGCTCAATCATTCGAATCGTCGGATTATTATTAGCACTTTTTAGTGTATCAATGCTCGCACCTGCGCTCGT
CGCACTGATCTATAGAGATGGTGCGGGTGTGCCATTTGTGACGACTTTCTTCGTTCTATTATTTTGTGGAGCAACTTGCT
GGTTTCCAAACCGACGCTATAAACATGAATTGAAGGCGCGAGATGGCTTTCTCATTGTGGTGTTGTTCTGGACGGTAATC
GGCAGTGCAGGAGCATTGCCGTTTTTGATCGCGGATAATCCGAGCGTTTCCGTTACTGATGCCTTTTTTGAATCGTTTTC
TGCATTAACAACGACAGGTGCAACCGTAATTGTTGGCCTCGATGATCTCCCTAAAGCAATTCTATTTTACCGCCAATTCC
TGCAATGGTTTGGTGGTATGGGTATCATCGTATTGGCGGTAGCCATCCTTCCTGTTCTGGGCATCGGTGGTATGCAGCTA
TATCGTGCTGAAATACCGGGTCCAGTAAAAGACAGTAAGATGACCCCGCGTATTGCTGAAACGGCAAAAGCGCTCTGGTA
CATCTATTTAAGCTTAACTATTGCTTGTGCGGTGGCATTTTGGCTTGCAGGCATGAGTTTCTTTGATGCCATCAGTCATA
GTTTCTCAACTATTGCGATTGGTGGGTTCTCGACTCACGATGCAAGTATGGGTTATTTCAATAGCCCTGCTATCAACATG
ATTACGGTCGTGTTCCTTCTTATATCTGCATGTAACTATTCTCTTCACTTTGCGGCATTTGCTTCTGGTGGCGTACATCC
TAAATATTACTGGAAAGACCCTGAGTTTCGCGCTTTTATCTTTATTCAAGTCGTCCTGTTCTTAGTTTGTTTCTTATTAC
TGCTGAATCATCACTCTTATGACTCGTATTACGATGCCTTTGACCAAGCATTGTTCCAAACTGTATCTATATCTACGACA
GCAGGCTTCACTACTACTGGTTTCTCCGAGTGGCCGCTATTTTTACCTGTTCTGCTTTTGTTCTCTTCTTTTATAGGGGG
ATGTGCAGGTTCAACCGGTGGCGGTATGAAAGTCATCCGAATATTACTCCTTACGCTGCAAGGTGCTCGTGAAATGAAGC
GTCTTGTTCACCCGCGCGCTGTCTATACCATTAAGGTTGGCGGTTCTGCATTACCACAACGTGTCGTGGATGCGGTTTGG
GGATTCTTTTCTGCATACGCATTGGTGTTTGTGGTTTGTATGTTGGCGCTGATTGCAACCGGTATGGATGAGCTGAGCGC
CTTCTCTGCCGTAGCCGCAACATTGAATAACCTTGGCCCGGGCTTAGGTGAAGTGGCAATGCACTTCGGCGATGTGAATG
ACAAGGCTAAGTGGGTGTTGATCGTATCTATGCTGTTTGGTCGTTTAGAGATATTCACCTTATTAATTTTATTGACCCCT
ACGTTTTGGCGTAGCTAA

Upstream 100 bases:

>100_bases
TTTACCCAAACCATGATCAATAAAAGCGGTGCTAAGGCACTGGTAACGAAAGTCAAAGACAACTAGGAAGTGTGAAGCAT
TTCGCTTCGTTCAATAGCTC

Downstream 100 bases:

>100_bases
GGACAACATTGTGGCAAAAGCTCTATTTTTGTATTCAAGCCGTGAAGGGCAGACCAAGAAAATCTTGAACTATATAAAAG
AAGAAATGAATGAGTTCGAA

Product: Trk system potassium uptake protein trkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MQFRSIIRIVGLLLALFSVSMLAPALVALIYRDGAGVPFVTTFFVLLFCGATCWFPNRRYKHELKARDGFLIVVLFWTVI
GSAGALPFLIADNPSVSVTDAFFESFSALTTTGATVIVGLDDLPKAILFYRQFLQWFGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLSLTIACAVAFWLAGMSFFDAISHSFSTIAIGGFSTHDASMGYFNSPAINM
ITVVFLLISACNYSLHFAAFASGGVHPKYYWKDPEFRAFIFIQVVLFLVCFLLLLNHHSYDSYYDAFDQALFQTVSISTT
AGFTTTGFSEWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLTLQGAREMKRLVHPRAVYTIKVGGSALPQRVVDAVW
GFFSAYALVFVVCMLALIATGMDELSAFSAVAATLNNLGPGLGEVAMHFGDVNDKAKWVLIVSMLFGRLEIFTLLILLTP
TFWRS

Sequences:

>Translated_485_residues
MQFRSIIRIVGLLLALFSVSMLAPALVALIYRDGAGVPFVTTFFVLLFCGATCWFPNRRYKHELKARDGFLIVVLFWTVI
GSAGALPFLIADNPSVSVTDAFFESFSALTTTGATVIVGLDDLPKAILFYRQFLQWFGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLSLTIACAVAFWLAGMSFFDAISHSFSTIAIGGFSTHDASMGYFNSPAINM
ITVVFLLISACNYSLHFAAFASGGVHPKYYWKDPEFRAFIFIQVVLFLVCFLLLLNHHSYDSYYDAFDQALFQTVSISTT
AGFTTTGFSEWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLTLQGAREMKRLVHPRAVYTIKVGGSALPQRVVDAVW
GFFSAYALVFVVCMLALIATGMDELSAFSAVAATLNNLGPGLGEVAMHFGDVNDKAKWVLIVSMLFGRLEIFTLLILLTP
TFWRS
>Mature_485_residues
MQFRSIIRIVGLLLALFSVSMLAPALVALIYRDGAGVPFVTTFFVLLFCGATCWFPNRRYKHELKARDGFLIVVLFWTVI
GSAGALPFLIADNPSVSVTDAFFESFSALTTTGATVIVGLDDLPKAILFYRQFLQWFGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLSLTIACAVAFWLAGMSFFDAISHSFSTIAIGGFSTHDASMGYFNSPAINM
ITVVFLLISACNYSLHFAAFASGGVHPKYYWKDPEFRAFIFIQVVLFLVCFLLLLNHHSYDSYYDAFDQALFQTVSISTT
AGFTTTGFSEWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLTLQGAREMKRLVHPRAVYTIKVGGSALPQRVVDAVW
GFFSAYALVFVVCMLALIATGMDELSAFSAVAATLNNLGPGLGEVAMHFGDVNDKAKWVLIVSMLFGRLEIFTLLILLTP
TFWRS

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=485, Percent_Identity=68.8659793814433, Blast_Score=643, Evalue=0.0,
Organism=Escherichia coli, GI1787626, Length=482, Percent_Identity=42.1161825726141, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53066; Mature: 53066

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFRSIIRIVGLLLALFSVSMLAPALVALIYRDGAGVPFVTTFFVLLFCGATCWFPNRRY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHCCCCCHH
KHELKARDGFLIVVLFWTVIGSAGALPFLIADNPSVSVTDAFFESFSALTTTGATVIVGL
HHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEC
DDLPKAILFYRQFLQWFGGMGIIVLAVAILPVLGIGGMQLYRAEIPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCHHHH
TAKALWYIYLSLTIACAVAFWLAGMSFFDAISHSFSTIAIGGFSTHDASMGYFNSPAINM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHH
ITVVFLLISACNYSLHFAAFASGGVHPKYYWKDPEFRAFIFIQVVLFLVCFLLLLNHHSY
HHHHHHHHHHCCCCEEEEEHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DSYYDAFDQALFQTVSISTTAGFTTTGFSEWPLFLPVLLLFSSFIGGCAGSTGGGMKVIR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ILLLTLQGAREMKRLVHPRAVYTIKVGGSALPQRVVDAVWGFFSAYALVFVVCMLALIAT
HHHHHHHCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMDELSAFSAVAATLNNLGPGLGEVAMHFGDVNDKAKWVLIVSMLFGRLEIFTLLILLTP
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TFWRS
HHHCC
>Mature Secondary Structure
MQFRSIIRIVGLLLALFSVSMLAPALVALIYRDGAGVPFVTTFFVLLFCGATCWFPNRRY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHCCCCCHH
KHELKARDGFLIVVLFWTVIGSAGALPFLIADNPSVSVTDAFFESFSALTTTGATVIVGL
HHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEC
DDLPKAILFYRQFLQWFGGMGIIVLAVAILPVLGIGGMQLYRAEIPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCHHHH
TAKALWYIYLSLTIACAVAFWLAGMSFFDAISHSFSTIAIGGFSTHDASMGYFNSPAINM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHH
ITVVFLLISACNYSLHFAAFASGGVHPKYYWKDPEFRAFIFIQVVLFLVCFLLLLNHHSY
HHHHHHHHHHCCCCEEEEEHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DSYYDAFDQALFQTVSISTTAGFTTTGFSEWPLFLPVLLLFSSFIGGCAGSTGGGMKVIR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ILLLTLQGAREMKRLVHPRAVYTIKVGGSALPQRVVDAVWGFFSAYALVFVVCMLALIAT
HHHHHHHCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMDELSAFSAVAATLNNLGPGLGEVAMHFGDVNDKAKWVLIVSMLFGRLEIFTLLILLTP
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TFWRS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]