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The map label for this gene is dsdX

Identifier: 218702465

GI number: 218702465

Start: 4391185

End: 4392522

Strand: Direct

Name: dsdX

Synonym: ECIAI39_4220

Alternate gene names: 218702465

Gene position: 4391185-4392522 (Clockwise)

Preceding gene: 218702462

Following gene: 218702466

Centisome position: 85.56

GC content: 49.63

Gene sequence:

>1338_bases
ATGCACTCTCAAATCTGGGTTGTGAGCACGCTGCTTATCAGCATCGTGTTAATTGTACTGGCCATCGTGAAGTTCAAATT
CCACCCGTTTCTGGCGCTGTTGCTGGCCAGCTTCTTCGTGGGAACGATGATGGGTATGGGGCCACTGGATATGGTAAATG
CTATTGAAAGTGGAATTGGCGGAACGCTGGGGTTCCTCGCTGCGGTTATCGGCCTTGGCACGATACTGGGAAAAATGATG
GAAGTATCCGGGGCCGCAGAAAGAATTGGTCTGACACTTCAACGCTGCCGGTGGCTTTCGGCTGATGTCATTATGGTGCT
GGTTGGCCTGATTTGCGGCATCACGCTGTTTGTTGAAGTGGGCGTCGTGCTATTGATTCCTCTGGCTTTTTCAATTGCCA
AAAAAACCAATACCTCATTGTTAAAGCTGGCCATTCCGCTGTGTACCGCATTGATGGCAGTGCACTGCGTGGTTCCCCCA
CATCCGGCTGCTTTATATGTTGCCAATAAGCTGGGCGCAGATATCGGTTCGGTGATCGTCTACGGTTTGCTGGTTGGGCT
GATGGCATCACTGATCGGTGGCCCACTTTTCCTTAAATTTCTGGGGCAACGACTGCCCTTTAAACCTGTACCCACAGAGT
TTGCCGATCTCAAAGTTCGCGATGAAAAAATACTACCGTCATTAGGCGCAACGTTATTCACCATACTGCTACCCATTGCG
CTGATGTTGGTTAAAACGATTGCCGAATTGAATATGGCGCGTGAGAGTGGTTTGTATACCTTGCTTGAGTTTATTGGCAA
CCCTATCACTGCCATGTTTATCGCCGTGTTTGTCGCCTATTATGTGTTGGGTATACGTCAGCATATGAGCATGGGGACGA
TGCTCACACATACGGAAAATGGTTTCGGTTCTATTGCTAATATTTTGCTGATTATCGGGGCCGGAGGCGCATTCAACGCC
ATTTTAAAAAGCAGCAGTCTCGCTGATACGCTGGCAGTTATTCTCTCTAATATGCATATGCACCCGATTCTTCTGGCCTG
GTTGGTGGCACTTATTCTGCATGCTGCTGTGGGCTCCGCTACGGTGGCAATGATGGGGGCAACGGCAATTGTTGCCCCCA
TGCTGCCGCTGTATCCCGACATCAGCCCGGAAATTATTGCGATTGCTATCGGTTCCGGTGCGATTGGCTGCACGATCGTT
ACGGACTCGCTTTTCTGGCTGGTGAAGCAATATTGCGGCGCTACGCTCAATGAAACATTTAAATACTATACGACAGCGAC
ATTTATCGCTTCGGTCGTCGCTCTGGCGGGCACATTCCTGCTGTCATTTATCATCTAA

Upstream 100 bases:

>100_bases
GATGCAATTTAGCTCATGTGAAAGGCAAATTTTATCGTTTGTCAGCCTGCGTTGTTTTTTTGTCCAATATCATCAGGTTA
ATCACAGGGGAAGGTGAGAT

Downstream 100 bases:

>100_bases
GCGCAAAGAGACGTACTATGGAAAACGCTAAAATGAATTCGCTCATCGCCCAGTATCCGTTGGTAGAGGATCTGGTTGCT
CTTAAAGAAGCCACCTGGTT

Product: permease DsdX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MHSQIWVVSTLLISIVLIVLAIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
HPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKILPSLGATLFTILLPIA
LMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNA
ILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII

Sequences:

>Translated_445_residues
MHSQIWVVSTLLISIVLIVLAIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
HPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKILPSLGATLFTILLPIA
LMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNA
ILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII
>Mature_445_residues
MHSQIWVVSTLLISIVLIVLAIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
HPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKILPSLGATLFTILLPIA
LMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNA
ILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII

Specific function: Probable permease for an unknown substrate [H]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI1788707, Length=445, Percent_Identity=98.876404494382, Blast_Score=865, Evalue=0.0,
Organism=Escherichia coli, GI48994935, Length=440, Percent_Identity=36.8181818181818, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1790716, Length=430, Percent_Identity=32.5581395348837, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI1790776, Length=427, Percent_Identity=31.615925058548, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI2367370, Length=427, Percent_Identity=33.7236533957845, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI48994939, Length=429, Percent_Identity=35.6643356643357, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789097, Length=437, Percent_Identity=29.7482837528604, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47120; Mature: 47120

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSQIWVVSTLLISIVLIVLAIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
GTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPPHPAALYVANKLGADIGSVIV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHH
YGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKILPSLGATLFTILLPIA
HHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHHCCEECHHHHHHHHHHHHHHHHHHHH
LMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTEN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHEECCC
GFGSIANILLIIGAGGAFNAILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSA
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETF
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
KYYTTATFIASVVALAGTFLLSFII
HHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MHSQIWVVSTLLISIVLIVLAIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
GTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPPHPAALYVANKLGADIGSVIV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHH
YGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKILPSLGATLFTILLPIA
HHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHHCCEECHHHHHHHHHHHHHHHHHHHH
LMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAVFVAYYVLGIRQHMSMGTMLTHTEN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHEECCC
GFGSIANILLIIGAGGAFNAILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSA
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETF
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
KYYTTATFIASVVALAGTFLLSFII
HHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592420; 3275618; 9205837; 9278503; 3029015; 1659648; 12218016 [H]