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The map label for this gene is dsdA

Identifier: 218702466

GI number: 218702466

Start: 4392540

End: 4393871

Strand: Direct

Name: dsdA

Synonym: ECIAI39_4221

Alternate gene names: 218702466

Gene position: 4392540-4393871 (Clockwise)

Preceding gene: 218702465

Following gene: 218702471

Centisome position: 85.59

GC content: 51.28

Gene sequence:

>1332_bases
ATGGAAAACGCTAAAATGAATTCGCTCATCGCCCAGTATCCGTTGGTAGAGGATCTGGTTGCTCTTAAAGAAGCCACCTG
GTTTAATCCTGGCACTACCTCATTGGCAGAAGGTTTACCTTATGTTGGCCTGACCGAACAGGATGTTCAGGACGCCCATG
CGCGCTTATCCCGTTTTGCACCCTATCTGGCAAAAGCATTTCCTGAAACTGCTGCCACTGGGGGGATTATTGAATCAGAA
CTGGTTGCCATTCCGGCTATGCAAAAACGGCTGGAAAAGGAATATCAACAACCGATCTGTGGGCAACTGTTACTGAAAAA
AGATAGCCATTTGCCTATTTCCGGCTCCATAAAAGCACGCGGCGGGATTTATGAAGTCCTGGCACATGCAGAAAGACTGG
CTCTGGAAGCGGGGTTGCTGACGCTTGAAGATGACTACAGCAAACTGCTTTCCCCGGAGTTTAAACAGTTCTTTAGTCAA
TACAGCATTGCTGTGGGCTCAACCGGAAATCTGGGGTTATCAATCGGCATAATGAGCGCCCGCATTGGCTTTAAGGTGAC
AGTGCATATGTCTGCTGATGCCCGGGCGTGGAAAAAAGCGAAACTGCGCAGCCATGGCGTTACGGTCGTGGAATATGAGC
AAGATTATGGTGTTGCTGTCGAGGAAGGACGTAAAGCAGCGCAGTCTGACCCGAACTGTTTCTTTATTGATGATGAGAAT
TCCCGCACGTTGTTCCTTGGGTATTCCGTCGCTGGCCAGCGTCTTAAAGCGCAATTTGCCCAGCAAGGCCGTATCGTCGA
TGCTGATAACCCTCTGTTTGTCTATATGCCGTGTGGTGTTGGCGGTGGTCCTGGTGGCGTCGCATTCGGACTTAAACTGG
CGTTTGGCGATCATGTTCACTGCTTTTTTGCCGAACCAACACACTCCCCGTGTATGTTATTAGGCGTCCATACCGGATTA
CACGATCAGATTTCTGTTCAGGATATTGGCATCGACAACCTTACCGCTGCCGATGGCCTTGCGGTTGGTCGCGCATCGGG
CTTTGTCGGGCGGGCGATGGAGCGTCTGCTGGATGGCTTCTATACCCTTAGCGATCAAACCATGTATGACATGCTTGGCT
GGCTGGCGCAGGAAGAAGGTATTCGTCTTGAACCTTCGGCACTGGCGGGTATGGCCGGGCCTCAGCGCGTGTGCGCATCA
GTAAGTTACCAACAGATGCACGGTTTCAGCGCAGAACAACTGCGTAATGCCACTCATCTGGTGTGGGCGACGGGAGGTGG
AATGGTGCCGGAAGAAGAAATGGAACAATATCTGGCTAAGGGCACTGACTAA

Upstream 100 bases:

>100_bases
CATTTAAATACTATACGACAGCGACATTTATCGCTTCGGTCGTCGCTCTGGCGGGCACATTCCTGCTGTCATTTATCATC
TAAGCGCAAAGAGACGTACT

Downstream 100 bases:

>100_bases
GGGCCACTAATGATTTTTTATGCCACATCGACTCTCTTTTTGTGGGAAAATGATGTGGCTCAAAGATACTTCATATCTTT
TGTCTGATGTAGCCCCCTGA

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MENAKMNSLIAQYPLVEDLVALKEATWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESE
LVAIPAMQKRLEKEYQQPICGQLLLKKDSHLPISGSIKARGGIYEVLAHAERLALEAGLLTLEDDYSKLLSPEFKQFFSQ
YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYMPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGL
HDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCAS
VSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMEQYLAKGTD

Sequences:

>Translated_443_residues
MENAKMNSLIAQYPLVEDLVALKEATWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESE
LVAIPAMQKRLEKEYQQPICGQLLLKKDSHLPISGSIKARGGIYEVLAHAERLALEAGLLTLEDDYSKLLSPEFKQFFSQ
YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYMPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGL
HDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCAS
VSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMEQYLAKGTD
>Mature_443_residues
MENAKMNSLIAQYPLVEDLVALKEATWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESE
LVAIPAMQKRLEKEYQQPICGQLLLKKDSHLPISGSIKARGGIYEVLAHAERLALEAGLLTLEDDYSKLLSPEFKQFFSQ
YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYMPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGL
HDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCAS
VSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMEQYLAKGTD

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788708, Length=441, Percent_Identity=98.1859410430839, Blast_Score=896, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.18 [H]

Molecular weight: Translated: 47993; Mature: 47993

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENAKMNSLIAQYPLVEDLVALKEATWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFA
CCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHH
PYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPICGQLLLKKDSHLPISGSIKAR
HHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCC
GGIYEVLAHAERLALEAGLLTLEDDYSKLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSA
CCHHHHHHHHHHHHHHHCCEEECCHHHHHCCHHHHHHHHHHEEEECCCCCCEEEEEEEEE
RIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
CCCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCHHHCCCCCEEEEECCC
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYMPCGVGGGPGGVAFGLKLAFGDHVH
CCEEEEEEHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCEEEEEEEECCEEE
CFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGF
EEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCASVSYQQMHGFSAEQLRNATHL
HCCCCCHHHHHHHHHHHCCCCEECHHHHHCCCCHHHHHHHCCHHHHCCCCHHHHCCCEEE
VWATGGGMVPEEEMEQYLAKGTD
EEECCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MENAKMNSLIAQYPLVEDLVALKEATWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFA
CCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHH
PYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPICGQLLLKKDSHLPISGSIKAR
HHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCC
GGIYEVLAHAERLALEAGLLTLEDDYSKLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSA
CCHHHHHHHHHHHHHHHCCEEECCHHHHHCCHHHHHHHHHHEEEECCCCCCEEEEEEEEE
RIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
CCCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCHHHCCCCCEEEEECCC
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYMPCGVGGGPGGVAFGLKLAFGDHVH
CCEEEEEEHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCEEEEEEEECCEEE
CFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGF
EEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCASVSYQQMHGFSAEQLRNATHL
HCCCCCHHHHHHHHHHHCCCCEECHHHHHCCCCHHHHHHHCCHHHHCCCCHHHHCCCEEE
VWATGGGMVPEEEMEQYLAKGTD
EEECCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA