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The map label for this gene is sgbU

Identifier: 218702348

GI number: 218702348

Start: 4264144

End: 4265004

Strand: Direct

Name: sgbU

Synonym: ECIAI39_4094

Alternate gene names: 218702348

Gene position: 4264144-4265004 (Clockwise)

Preceding gene: 218702347

Following gene: 218702349

Centisome position: 83.09

GC content: 55.87

Gene sequence:

>861_bases
GTGCGTAATCATCCGTTAGGGATTTATGAAAAAGCGCTGGCGAAAGATCTCTCCTGGCCGGAGCGGCTGGTGCTGGCAAA
AAGCTGTGGCTTTGATTTTGTCGAAATGTCGGTGGATGAAACCGACGAACGGCTCTCACGCCTTGACTGGAGCGCCGCAC
AACGTGCTTCGCTGGTCACTGCGATGATCGAAACGGGTGTTGCCATTCCGTCAATGTGCCTGTCTGCCCATCGTCGTTTT
CCCTTTGGCAGCCGGGACGAGGCAGTGCGCGAACGGGCGCGGGAAATCATGAGTAAAGCGATTCGCCTGGCGCGCGATCT
CGGCATTCGCACCATCCAGCTGGCAGGTTATGACGTCTATTACGAAGACCACGACGAAGGCACCCAACAACGTTTTGCTG
AAGGGCTGGCGTGGGCAGTCGAACAGGCGGCGGCATCACAAGTTATGCTGGCGGTGGAGATTATGGATACCGCGTTTATG
AACTCCATCAGCAAATGGAAAAAATGGGACGAGATGCTCGCCTCGCCGTGGTTCACCGTCTACCCGGACGTCGGCAACCT
CAGCGCCTGGGGCAATGATGTTCCCGCCGAACTGAAACTGGGCATTGACCGTATCGCCGCGATCCACCTGAAAGACACCC
AGCCAGTGACCGAGCAAAGCCCCGGACAGTTCCGTGATGTGCCGTTTGGCGAAGGCTGCGTCGATTTCGTTGGCATCTTC
AAAACGCTGCATGAACTGAACTATCGCGGATCATTTCTGATTGAGATGTGGACCGAAAAAGCCAAAGAGCCGGTGCTGGA
GATTATTCAGGCGCGGCGCTGGATTGAAGCGCGTATGCAGGAGGCCGGATTTATATGTTAG

Upstream 100 bases:

>100_bases
AAAGCGTTTATTGCCGGGCGAGCACTGGCAGGCGCAGCAAATCCGGTGCAGGTGGCTGGCGATTTCCATGCACAAATTGA
TGCCATCTGGGGAGGTGCGC

Downstream 100 bases:

>100_bases
AGCAACTAAAAGCCGACGTGCTGGCGGCGAATCTGGCGCTTCCCGTTCATCATCTGGTGACGTTCACCTGGGGCAATGTC
AGCGCGGTAGACGAAACGCG

Product: putative L-xylulose 5-phosphate 3-epimerase

Products: NA

Alternate protein names: L-xylulose-5-phosphate 3-epimerase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDERLSRLDWSAAQRASLVTAMIETGVAIPSMCLSAHRRF
PFGSRDEAVRERAREIMSKAIRLARDLGIRTIQLAGYDVYYEDHDEGTQQRFAEGLAWAVEQAAASQVMLAVEIMDTAFM
NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTEQSPGQFRDVPFGEGCVDFVGIF
KTLHELNYRGSFLIEMWTEKAKEPVLEIIQARRWIEARMQEAGFIC

Sequences:

>Translated_286_residues
MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDERLSRLDWSAAQRASLVTAMIETGVAIPSMCLSAHRRF
PFGSRDEAVRERAREIMSKAIRLARDLGIRTIQLAGYDVYYEDHDEGTQQRFAEGLAWAVEQAAASQVMLAVEIMDTAFM
NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTEQSPGQFRDVPFGEGCVDFVGIF
KTLHELNYRGSFLIEMWTEKAKEPVLEIIQARRWIEARMQEAGFIC
>Mature_286_residues
MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDERLSRLDWSAAQRASLVTAMIETGVAIPSMCLSAHRRF
PFGSRDEAVRERAREIMSKAIRLARDLGIRTIQLAGYDVYYEDHDEGTQQRFAEGLAWAVEQAAASQVMLAVEIMDTAFM
NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTEQSPGQFRDVPFGEGCVDFVGIF
KTLHELNYRGSFLIEMWTEKAKEPVLEIIQARRWIEARMQEAGFIC

Specific function: Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate (Potential). May be involved in the utilization of 2,3-diketo-L-gulonate [H]

COG id: COG3623

COG function: function code G; Putative L-xylulose-5-phosphate 3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HUMPI family [H]

Homologues:

Organism=Escherichia coli, GI87082294, Length=286, Percent_Identity=97.5524475524475, Blast_Score=577, Evalue=1e-166,
Organism=Escherichia coli, GI1790641, Length=281, Percent_Identity=58.7188612099644, Blast_Score=340, Evalue=6e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004560
- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =5.1.3.22 [H]

Molecular weight: Translated: 32483; Mature: 32483

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDERLSRLDWSAAQRASLVT
CCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHCHHHHHHHHHHH
AMIETGVAIPSMCLSAHRRFPFGSRDEAVRERAREIMSKAIRLARDLGIRTIQLAGYDVY
HHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEEEE
YEDHDEGTQQRFAEGLAWAVEQAAASQVMLAVEIMDTAFMNSISKWKKWDEMLASPWFTV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
YPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTEQSPGQFRDVPFGEGCVDFVGIF
CCCCCCCCCCCCCCCHHHHHCHHHHEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
KTLHELNYRGSFLIEMWTEKAKEPVLEIIQARRWIEARMQEAGFIC
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDERLSRLDWSAAQRASLVT
CCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHCHHHHHHHHHHH
AMIETGVAIPSMCLSAHRRFPFGSRDEAVRERAREIMSKAIRLARDLGIRTIQLAGYDVY
HHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEEEE
YEDHDEGTQQRFAEGLAWAVEQAAASQVMLAVEIMDTAFMNSISKWKKWDEMLASPWFTV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
YPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTEQSPGQFRDVPFGEGCVDFVGIF
CCCCCCCCCCCCCCCHHHHHCHHHHEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
KTLHELNYRGSFLIEMWTEKAKEPVLEIIQARRWIEARMQEAGFIC
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]