Click here to switch to the map view.

The map label for this gene is yedW

Identifier: 218699471

GI number: 218699471

Start: 1168045

End: 1168716

Strand: Direct

Name: yedW

Synonym: ECIAI39_1088

Alternate gene names: 218699471

Gene position: 1168045-1168716 (Clockwise)

Preceding gene: 218699464

Following gene: 218699472

Centisome position: 22.76

GC content: 44.79

Gene sequence:

>672_bases
ATGAAGATTCTACTTATTGAAGATAATCAAAGGACCCAGGAATGGGTAACGCAGGGGCTTTCCGAAGCGGGTTATGTCAT
TGATGCCGTTTCTGATGGCAGAGATGGGCTTTATCTTGCGCTGAAGGATGATTATGCATTGATCATTCTGGATATTATGC
TTCCGGGTATGGATGGCTGGCAGATCTTACAAACGTTGAGAACGGCAAAGCAAACCCCTGTTATTTGCCTTACTGCAAGG
GATTCTGTCGATGACAGAGTCAGAGGGCTGGACAGTGGGGCAAATGATTATCTGGTAAAACCTTTTTCATTTTCTGAGTT
GCTGGCAAGGGTTCGGGCACAATTAAGGCAACATTACACTCTGAATTCAACATTAGAAATCAGTGGCTTAAAAATGGACT
CTGTCAGTCAAAGTGTGAGCAGGGACAATATCAGTATTACACTGACGCGCAAGGAGTTTCAGTTACTTTGGCTACTGGCC
TCCAGAGCTGGCGAGATTATACCCAGAACGGTTATTGCGAGTGAAATTTGGGGAATCAACTTTGATAGTGATACCAATAC
GGTGGATGTCGCCATTCGCAGGCTCCGCGCAAAAGTTGATGATCCTTTTCCTGAAAAGCTAATCGCCACAATCCGGGGGA
TGGGCTATTCATTCGTAGCGGTAAAAAAATAA

Upstream 100 bases:

>100_bases
GGATAGCGAAAAAACGTCCAGGGTAACCTTACAGCAGCATTACAATTTTGTAATGAACCAGGTTGTTTCTATAACATATG
ATTTATGGCATATTATTTTC

Downstream 100 bases:

>100_bases
TGAAAAGATTATCTATAACCGTCCGTTTAACCTTGCTTTTTATATTGCTGCTGTCTGTTGCTGGCGCTGGAATTGTATGG
ACTCTCTATAATGGCCTGGC

Product: transcriptional regulatory protein YedW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQILQTLRTAKQTPVICLTAR
DSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQHYTLNSTLEISGLKMDSVSQSVSRDNISITLTRKEFQLLWLLA
SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSFVAVKK

Sequences:

>Translated_223_residues
MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQILQTLRTAKQTPVICLTAR
DSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQHYTLNSTLEISGLKMDSVSQSVSRDNISITLTRKEFQLLWLLA
SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSFVAVKK
>Mature_223_residues
MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQILQTLRTAKQTPVICLTAR
DSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQHYTLNSTLEISGLKMDSVSQSVSRDNISITLTRKEFQLLWLLA
SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSFVAVKK

Specific function: Probable member of a two-component regulatory system yedW/yedV [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=98.2062780269058, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1786784, Length=219, Percent_Identity=51.1415525114155, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=37.8378378378378, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=34.9775784753363, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=36.3636363636364, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=32.3144104803493, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=35.042735042735, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=31.5315315315315, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=28.6363636363636, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.9366515837104, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=30.8695652173913, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=30.4347826086957, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=29.8245614035088, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=30.0448430493274, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=31.7757009345794, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=118, Percent_Identity=30.5084745762712, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25037; Mature: 25037

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGW
CEEEEEECCCHHHHHHHHCHHHCCEEEEEECCCCCCEEEEEECCCEEEEEEECCCCCCHH
QILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQHYT
HHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCC
LNSTLEISGLKMDSVSQSVSRDNISITLTRKEFQLLWLLASRAGEIIPRTVIASEIWGIN
CCCEEEEECCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCE
FDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSFVAVKK
ECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEC
>Mature Secondary Structure
MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGW
CEEEEEECCCHHHHHHHHCHHHCCEEEEEECCCCCCEEEEEECCCEEEEEEECCCCCCHH
QILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQHYT
HHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCC
LNSTLEISGLKMDSVSQSVSRDNISITLTRKEFQLLWLLASRAGEIIPRTVIASEIWGIN
CCCEEEEECCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCE
FDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSFVAVKK
ECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]