Click here to switch to the map view.

The map label for this gene is yedV

Identifier: 218699472

GI number: 218699472

Start: 1168716

End: 1170074

Strand: Direct

Name: yedV

Synonym: ECIAI39_1089

Alternate gene names: 218699472

Gene position: 1168716-1170074 (Clockwise)

Preceding gene: 218699471

Following gene: 218699476

Centisome position: 22.77

GC content: 39.74

Gene sequence:

>1359_bases
ATGAAAAGATTATCTATAACCGTCCGTTTAACCTTGCTTTTTATATTGCTGCTGTCTGTTGCTGGCGCTGGAATTGTATG
GACTCTCTATAATGGCCTGGCAAGTGAGTTGAAATGGCGCGATGATACAACACTCATTAACCGGACAGCGCAGATCAAGC
AGTTGTTAATTGATGGGGTAAATCCAGATACGTTACCTGTGTACTTTAACCGGATGATGGATGTTAGTCAGGATATTTTG
ATCATTCATGGTGATGGCATCAATAAAATTGTTAACCGGACAAATGTCAGTGATGACATGTTAAATAACATACCTGCTAG
TGAGACAATCAGCGCAGCAGGCATTTACAGAAGCATTATTAATGATACAGAGATAGATGCTTTCCGAATTAATATTGATG
AAGTTTCGCCATCATTAACGGTTACTGTGGCTAAATTGGCTTCAGCCAGACATAACATGCTTGAACAGTATAAAATTAAT
AGCATTATAATTTGCATTGTCGCCATTATATTGTGCTCAGTATTAAGTCCGTTGTTAATCAGAACGGGGTTGCGAGAGAT
CAAAAAGTTGAGTGGCGTAACGGAAGCGCTGAATTATAACGATAGCCGAGTGCCGGTTGAGGTTAGCGCATTACCGAGAG
AACTAAAACCTCTTGGGCAGGCGTTGAATAAAATGCATCATGCTTTAGTCAAAGATTTTGAGCGCCTTAGTCAATTTGCT
GACGATCTCGCTCATGAACTTAGAACGCCAATTAATGCATTACTGGGTCAGAATCAGGTTACGCTCAGTCAAACCAGAAG
TATCGCTGAATATCAAAAAACAATTGCCGGAAACATTGAAGAGCTGGAAAATATTTCGCGGTTAACAGAGAATATACTGT
TTCTTGCCAGGGCAGACAAAAACAATGTTTTGGTGAAACTGGATGCGCTTTCTCTCAATAAGGAAGTTGAAAATCTTTTG
GACTATCTTGAATATCTTTCAGACGAGAAAGAGATTCGTTTTAAGGTCGAGTGCAATCAACAAATCTTTGCGGATAAAAT
TTTACTGCAACGAATGTTATCGAATCTTATTGTTAACGCCATTCGATATTCACCAGAAAAATCGCGTATTCATATAACCA
GTTTTCTTGATGCCAACGGCTCTCTTAATATTGATATCGCCAGTCCTGGAACGAAAATTAATGAGCCTGAAAAACTCTTC
CGTAGATTTTGGCGGGGAGATAATTCGCGTCATTCCGTAGGTCAGGGACTTGGCCTTTCTTTAGTCAAAGCGATTGCCGA
ATTACATGGAGGAAGTGCTACGTATCACTATCTCAGTAAGCATAACGTGTTCCGAATTACGTTACCGCAAAGAAATTAA

Upstream 100 bases:

>100_bases
CCATTCGCAGGCTCCGCGCAAAAGTTGATGATCCTTTTCCTGAAAAGCTAATCGCCACAATCCGGGGGATGGGCTATTCA
TTCGTAGCGGTAAAAAAATA

Downstream 100 bases:

>100_bases
CATCGGGCTTCAGTACGCCATAAGTTAACCGTGAAAAAACGCAGCCACGTCGTGAGTATTAACGTGGCTGCGATTGATTA
TGCGCTTACATTACAATATA

Product: sensory kinase in two-component regulatory system with YedW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDIL
IIHGDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSIINDTEIDAFRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
SIIICIVAIILCSVLSPLLIRTGLREIKKLSGVTEALNYNDSRVPVEVSALPRELKPLGQALNKMHHALVKDFERLSQFA
DDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIAGNIEELENISRLTENILFLARADKNNVLVKLDALSLNKEVENLL
DYLEYLSDEKEIRFKVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLF
RRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLSKHNVFRITLPQRN

Sequences:

>Translated_452_residues
MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDIL
IIHGDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSIINDTEIDAFRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
SIIICIVAIILCSVLSPLLIRTGLREIKKLSGVTEALNYNDSRVPVEVSALPRELKPLGQALNKMHHALVKDFERLSQFA
DDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIAGNIEELENISRLTENILFLARADKNNVLVKLDALSLNKEVENLL
DYLEYLSDEKEIRFKVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLF
RRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLSKHNVFRITLPQRN
>Mature_452_residues
MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDIL
IIHGDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSIINDTEIDAFRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
SIIICIVAIILCSVLSPLLIRTGLREIKKLSGVTEALNYNDSRVPVEVSALPRELKPLGQALNKMHHALVKDFERLSQFA
DDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIAGNIEELENISRLTENILFLARADKNNVLVKLDALSLNKEVENLL
DYLEYLSDEKEIRFKVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLF
RRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLSKHNVFRITLPQRN

Specific function: Probable member of a two-component regulatory system yedW/yedV. May activate yedW by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788279, Length=452, Percent_Identity=97.5663716814159, Blast_Score=875, Evalue=0.0,
Organism=Escherichia coli, GI1786783, Length=295, Percent_Identity=34.5762711864407, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1786912, Length=215, Percent_Identity=30.2325581395349, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789403, Length=448, Percent_Identity=26.3392857142857, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788393, Length=315, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=24.6323529411765, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787894, Length=278, Percent_Identity=29.4964028776978, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=292, Percent_Identity=28.0821917808219, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=25.3333333333333, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789149, Length=213, Percent_Identity=25.3521126760563, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082128, Length=246, Percent_Identity=26.4227642276423, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR006290
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50770; Mature: 50770

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGV
CCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
NPDTLPVYFNRMMDVSQDILIIHGDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSII
CCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHH
NDTEIDAFRINIDEVSPSLTVTVAKLASARHNMLEQYKINSIIICIVAIILCSVLSPLLI
CCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTGLREIKKLSGVTEALNYNDSRVPVEVSALPRELKPLGQALNKMHHALVKDFERLSQFA
HHHHHHHHHHHHHHHHHCCCCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIAGNIEELENISRLTENILFLARADK
HHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECC
NNVLVKLDALSLNKEVENLLDYLEYLSDEKEIRFKVECNQQIFADKILLQRMLSNLIVNA
CCEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
IRYSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLFRRFWRGDNSRHSVGQGLGLS
HHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCHHH
LVKAIAELHGGSATYHYLSKHNVFRITLPQRN
HHHHHHHHCCCCCEEEEECCCCEEEEECCCCC
>Mature Secondary Structure
MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGV
CCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
NPDTLPVYFNRMMDVSQDILIIHGDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSII
CCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHH
NDTEIDAFRINIDEVSPSLTVTVAKLASARHNMLEQYKINSIIICIVAIILCSVLSPLLI
CCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTGLREIKKLSGVTEALNYNDSRVPVEVSALPRELKPLGQALNKMHHALVKDFERLSQFA
HHHHHHHHHHHHHHHHHCCCCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIAGNIEELENISRLTENILFLARADK
HHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECC
NNVLVKLDALSLNKEVENLLDYLEYLSDEKEIRFKVECNQQIFADKILLQRMLSNLIVNA
CCEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
IRYSPEKSRIHITSFLDANGSLNIDIASPGTKINEPEKLFRRFWRGDNSRHSVGQGLGLS
HHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCHHH
LVKAIAELHGGSATYHYLSKHNVFRITLPQRN
HHHHHHHHCCCCCEEEEECCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]