BacMap

Definition	Escherichia coli ED1a chromosome, complete genome.
Accession	NC_011745
Length	5,209,548

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The map label for this gene is yeaE [H]

Identifier: 218689722

GI number: 218689722

Start: 1939543

End: 1940397

Strand: Reverse

Name: yeaE [H]

Synonym: ECED1_1986

Alternate gene names: 218689722

Gene position: 1940397-1939543 (Counterclockwise)

Preceding gene: 218689723

Following gene: 218689719

Centisome position: 37.25

GC content: 49.82

Gene sequence:

>855_bases
ATGCAACAAAAAATGATTCAATTTAGTGGCGATGTCTCATTGCCAGCCATAGGGCAGGGAACATGGTATATGGGCGAAGA
TGCCAGTCAGCGTAAAACAGAAGTTGCTGCACTACGCGCGGGCATTGAACTCGGTTTAACCCTCATTGATACCGCCGAAA
TGTATGCCGATGGCGGTGCCGAAAAAGTGGTTGGGGAAGCATTAATCGGTCTGCGTGAGAACGTCTTTCTCGTCTCTAAA
GTCTATCCGTGGAATGCTGGCGGGCAAAAAGCGATAAATGCATGCGAAGCCAGTTTACGCCGTCTCAATACTGATTATCT
CGATCTCTACTTATTACACTGGTCTGGCAGTTTCGCTCTCGAAGAGACTGTCGCAGCGATGGAAAAATTGATCGCCCAGG
GAAAAATCCGCCGCTGGGGCGTTTCTAACCTTGATTATGCCGATATGCAGGAACTCTGGCAGCTGCCGGGGGGAAATCAG
TGTGCCACTAATCAGGTGCTTTACCATCTCGGTTCACGAGGGATTGAGTACGATCTACTTCCCTGGTGCCAGAAACAGCA
GATGCCGGTGATGGCTTACAGTCCATTAGCCCAGGCCGGGCGGTTGCGCAATGGACTGTTAAAAAACGCGGTAGTCAACG
AAATTGCACATGCTCACAATATCAGTGCGGCACAAGTATTGTTGGCGTGGGTAATCAGCCATCAGGGTGTGATGGCGATT
CCAAAAGCGGCAACTGTCGCACATGTCCAACAAAATGCGGCTGTGCTTGAGGTTGAACTTTCGTCAGCGGAATTAGTTAT
GCTGGATAAAGCGTATCCGGCACCAAAAGGAAAAACTGCGCTGGATATGGTGTGA

Upstream 100 bases:

>100_bases
ACAAATTCTGATAATGCATTTTTCCAGGGCATTTTGTGCATAAAAACAGGGCGTAATGCCCTGTTTTGCATTACGGTGGT
GCAATACCTGGGAGGAAGCA

Downstream 100 bases:

>100_bases
TGTTGATACGTGCCGGATGCATCGCACCCGGCACACAATATTAACGCAAATTAACGTTTCGCAACGCGAATGGATTGCGC
CAGATGTGCAGGTTTCTCTT

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALIGLRENVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFALEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQKQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
PKAATVAHVQQNAAVLEVELSSAELVMLDKAYPAPKGKTALDMV

Sequences:

>Translated_284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALIGLRENVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFALEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQKQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
PKAATVAHVQQNAAVLEVELSSAELVMLDKAYPAPKGKTALDMV
>Mature_284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALIGLRENVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFALEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQKQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
PKAATVAHVQQNAAVLEVELSSAELVMLDKAYPAPKGKTALDMV

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=297, Percent_Identity=29.2929292929293, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=29.811320754717, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI93277124, Length=303, Percent_Identity=27.7227722772277, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI24497577, Length=289, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI5174391, Length=289, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI5174695, Length=298, Percent_Identity=28.5234899328859, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4502049, Length=290, Percent_Identity=30.6896551724138, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI300116273, Length=288, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI310109922, Length=275, Percent_Identity=29.0909090909091, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI300116271, Length=276, Percent_Identity=27.1739130434783, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI24497585, Length=290, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI45446745, Length=295, Percent_Identity=27.4576271186441, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4503285, Length=295, Percent_Identity=27.4576271186441, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI310109920, Length=295, Percent_Identity=27.4576271186441, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI5453543, Length=295, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI24497583, Length=291, Percent_Identity=26.8041237113402, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI223718702, Length=182, Percent_Identity=32.4175824175824, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=97.5352112676056, Blast_Score=572, Evalue=1e-164,
Organism=Escherichia coli, GI1786400, Length=261, Percent_Identity=28.3524904214559, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87081735, Length=301, Percent_Identity=28.2392026578073, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI87082198, Length=258, Percent_Identity=29.8449612403101, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=26.984126984127, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=28.2051282051282, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789375, Length=323, Percent_Identity=23.8390092879257, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787674, Length=257, Percent_Identity=22.9571984435798, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17552492, Length=267, Percent_Identity=30.7116104868914, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17561298, Length=281, Percent_Identity=31.3167259786477, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=30.6859205776173, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17564128, Length=307, Percent_Identity=28.0130293159609, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17537077, Length=297, Percent_Identity=29.6296296296296, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17538386, Length=286, Percent_Identity=30.4195804195804, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17537075, Length=297, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17561300, Length=293, Percent_Identity=28.6689419795222, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17566692, Length=299, Percent_Identity=25.752508361204, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17550248, Length=294, Percent_Identity=25.5102040816327, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324694, Length=295, Percent_Identity=27.1186440677966, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322556, Length=283, Percent_Identity=27.5618374558304, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320079, Length=291, Percent_Identity=27.8350515463918, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=305, Percent_Identity=24.2622950819672, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24644950, Length=312, Percent_Identity=32.3717948717949, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI221378297, Length=332, Percent_Identity=30.7228915662651, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24657054, Length=289, Percent_Identity=26.643598615917, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=25.1724137931034, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24663317, Length=299, Percent_Identity=23.4113712374582, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356425, Length=298, Percent_Identity=24.1610738255034, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281366140, Length=252, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI20129731, Length=297, Percent_Identity=25.5892255892256, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24662789, Length=294, Percent_Identity=27.5510204081633, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24662781, Length=288, Percent_Identity=26.3888888888889, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24662785, Length=290, Percent_Identity=26.2068965517241, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30979; Mature: 30979

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHCCCH
EKVVGEALIGLRENVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAL
HHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHH
EETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQKQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEC
PKAATVAHVQQNAAVLEVELSSAELVMLDKAYPAPKGKTALDMV
CCHHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHCCCH
EKVVGEALIGLRENVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAL
HHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHH
EETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQKQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEC
PKAATVAHVQQNAAVLEVELSSAELVMLDKAYPAPKGKTALDMV
CCHHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]