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The map label for this gene is mipA [H]

Identifier: 218689723

GI number: 218689723

Start: 1940487

End: 1941233

Strand: Reverse

Name: mipA [H]

Synonym: ECED1_1987

Alternate gene names: 218689723

Gene position: 1941233-1940487 (Counterclockwise)

Preceding gene: 218689728

Following gene: 218689722

Centisome position: 37.26

GC content: 51.94

Gene sequence:

>747_bases
GTGACCAAACTCAAACTTCTGGCACTTGGAGTGCTTATCGCAACGTCTGCAGGCGTAACGCACGCTGAAGGTAAATTTTC
CCTGGGCGCAGGCGTAGGTGTCGTTGAACACCCATATAAAGATTACGATACCGATGTTTACCCAGTACCGGTAATCAACT
ATGAAGGCGATAACTTCTGGTTCCGTGGCTTAGGTGGTGGTTACTACCTGTGGAATGACGCAACGGACAAACTTTCAATT
ACCGCTTACTGGTCGCCGCTTTACTTCAAAGCTAAAGACAGTGGCGATCACCAAATGCGTCACCTGGATGACCGTAAGAG
CACCATGATGGCTGGTCTGTCTTATGCTCACTTTACCCAGTACGGTTACCTGCGTACCACCCTGGCTGGCGATACCCTGG
ATAACAGCAACGGCATCGTCTGGGATATGGCCTGGTTGTATCGTTACACCAACGGTGGCCTGACCGTGACTCCGGGTATT
GGTGTGCAGTGGAACAGCGAAAACCAGAACGAATACTATTATGGCGTATCGCGCAAAGAGTCCGCTCGCAGCGGTCTGCG
TGGCTATAACCCGAACGACAGCTGGAGCCCTTACCTGGAGCTGAGCGCCAGCTACAACTTCCTCGGTGACTGGAGTGTTT
ACGGTACCGCGCGCTACACCCGTCTGTCTGATGAAGTTACTGACAGCCCAATGGTGGATAAATCCTGGACTGGCCTGATT
TCTACCGGGATCACCTACAAATTCTGA

Upstream 100 bases:

>100_bases
CAGTTACTATAAAAAATGAAAACGTAAAAAGGTTGGGTTTCGATGTATTGACGGGTAAACTTTGTCGCCCGCTAAACATT
TGTTTAAGGAATGATTAATT

Downstream 100 bases:

>100_bases
TAATGCATTTTTCCAGGGCATTTTGTGCATAAAAACAGGGCGTAATGCCCTGTTTTGCATTACGGTGGTGCAATACCTGG
GAGGAAGCAATGCAACAAAA

Product: scaffolding protein for murein synthesizing machinery

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTKLKLLALGVLIATSAGVTHAEGKFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSI
TAYWSPLYFKAKDSGDHQMRHLDDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGI
GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTARYTRLSDEVTDSPMVDKSWTGLI
STGITYKF

Sequences:

>Translated_248_residues
MTKLKLLALGVLIATSAGVTHAEGKFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSI
TAYWSPLYFKAKDSGDHQMRHLDDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGI
GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTARYTRLSDEVTDSPMVDKSWTGLI
STGITYKF
>Mature_247_residues
TKLKLLALGVLIATSAGVTHAEGKFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSIT
AYWSPLYFKAKDSGDHQMRHLDDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGIG
VQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTARYTRLSDEVTDSPMVDKSWTGLIS
TGITYKF

Specific function: May serve as a scaffold protein required for the formation of a complex with mrcB/ponB and mltA, this complex could play a role in enlargement and septation of the murein sacculus [H]

COG id: COG3713

COG function: function code M; Outer membrane protein V

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mipA/ompV family [H]

Homologues:

Organism=Escherichia coli, GI1788082, Length=248, Percent_Identity=99.5967741935484, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1790010, Length=245, Percent_Identity=37.5510204081633, Blast_Score=184, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010583 [H]

Pfam domain/function: PF06629 MipA [H]

EC number: NA

Molecular weight: Translated: 27861; Mature: 27730

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLKLLALGVLIATSAGVTHAEGKFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFW
CCCCHHHHHEEHHHCCCCCEECCCCEEECCCCCEECCCCCCCCCCEEEEEEEEECCCCEE
FRGLGGGYYLWNDATDKLSITAYWSPLYFKAKDSGDHQMRHLDDRKSTMMAGLSYAHFTQ
EEECCCCEEEECCCCCEEEEEEEECEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHH
YGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGIGVQWNSENQNEYYYGVSRKE
CCEEEEEECCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCEEECCCCCCEEEEECCCCH
SARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTARYTRLSDEVTDSPMVDKSWTGLI
HHHHCCCCCCCCCCCCCEEEEEECCCEEECEEEECCEEEEEECCCCCCCCCCCCCCCCEE
STGITYKF
ECCEEECC
>Mature Secondary Structure 
TKLKLLALGVLIATSAGVTHAEGKFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFW
CCCHHHHHEEHHHCCCCCEECCCCEEECCCCCEECCCCCCCCCCEEEEEEEEECCCCEE
FRGLGGGYYLWNDATDKLSITAYWSPLYFKAKDSGDHQMRHLDDRKSTMMAGLSYAHFTQ
EEECCCCEEEECCCCCEEEEEEEECEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHH
YGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGIGVQWNSENQNEYYYGVSRKE
CCEEEEEECCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCEEECCCCCCEEEEECCCCH
SARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTARYTRLSDEVTDSPMVDKSWTGLI
HHHHCCCCCCCCCCCCCEEEEEECCCEEECEEEECCEEEEEECCCCCCCCCCCCCCCCEE
STGITYKF
ECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 10037771; 10806384 [H]