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The map label for this gene is msrB [H]

Identifier: 218689719

GI number: 218689719

Start: 1936774

End: 1937187

Strand: Reverse

Name: msrB [H]

Synonym: ECED1_1983

Alternate gene names: 218689719

Gene position: 1937187-1936774 (Counterclockwise)

Preceding gene: 218689722

Following gene: 218689718

Centisome position: 37.19

GC content: 48.07

Gene sequence:

>414_bases
ATGGCTAATAAACCTTCGGCAGAAGAACTGAAAAAAAATTTGTCCGAGATGCAGTTCTACGTGACGCAGAATCATGGGAC
AGAACCGCCATTTACGGGTCGTTTACTGCATAACAAGCGTGACGGCGTATATCACTGTTTGATCTGCGATGCCCCGCTGT
TTCATTCCCAAACCAAGTATGATTCCGGCTGTGGCTGGCCCAGTTTCTACGAACCGGTGAGTGAAGAATCTATTCGTTAT
ATCAAAGACTTGTCACATGGAATGCAGCGCATAGAAATTCGTTGCGGTAACTGCGATGCCCATCTGGGCCATGTCTTCCC
TGACGGGCCGCATCCAACGGGCGAACGTTATTGTGTTAACTCTGCTTCTTTACGCTTCACTGATGGCGAAAACGGCGAAG
AAATCAACGGTTGA

Upstream 100 bases:

>100_bases
CGTCGAGATCAAGTTTAGGACAAAATTTTGCCAGTTGGTGTTAATGTTTTGTTAGAATCAGTCACGTAATGTGAGCACGA
TTAAAGTGAGATGTGAGCAA

Downstream 100 bases:

>100_bases
AAAAACGATTCAGCAACTTATTCCACAGGAGCGGAAAAATTATGAATCTTGAGGACATTATCAACAGCATGACGCCTGAA
GTATACCAGCGTTTGTCGAC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRY
IKDLSHGMQRIEIRCGNCDAHLGHVFPDGPHPTGERYCVNSASLRFTDGENGEEING

Sequences:

>Translated_137_residues
MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRY
IKDLSHGMQRIEIRCGNCDAHLGHVFPDGPHPTGERYCVNSASLRFTDGENGEEING
>Mature_136_residues
ANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYI
KDLSHGMQRIEIRCGNCDAHLGHVFPDGPHPTGERYCVNSASLRFTDGENGEEING

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=132, Percent_Identity=50, Blast_Score=156, Evalue=6e-39,
Organism=Homo sapiens, GI301336162, Length=132, Percent_Identity=50, Blast_Score=156, Evalue=6e-39,
Organism=Homo sapiens, GI73089054, Length=132, Percent_Identity=50, Blast_Score=156, Evalue=6e-39,
Organism=Homo sapiens, GI37620216, Length=132, Percent_Identity=50, Blast_Score=155, Evalue=7e-39,
Organism=Homo sapiens, GI117606353, Length=128, Percent_Identity=53.125, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788077, Length=137, Percent_Identity=99.2700729927007, Blast_Score=288, Evalue=7e-80,
Organism=Caenorhabditis elegans, GI17553450, Length=120, Percent_Identity=49.1666666666667, Blast_Score=115, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI115532676, Length=120, Percent_Identity=49.1666666666667, Blast_Score=115, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6319816, Length=132, Percent_Identity=43.1818181818182, Blast_Score=108, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24645799, Length=124, Percent_Identity=49.1935483870968, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI45553335, Length=124, Percent_Identity=49.1935483870968, Blast_Score=133, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21356369, Length=124, Percent_Identity=49.1935483870968, Blast_Score=133, Evalue=4e-32,
Organism=Drosophila melanogaster, GI221378664, Length=121, Percent_Identity=50.4132231404959, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24645801, Length=135, Percent_Identity=45.1851851851852, Blast_Score=129, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24645804, Length=135, Percent_Identity=45.1851851851852, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI221378662, Length=128, Percent_Identity=47.65625, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15460; Mature: 15329

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKY
CCCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCC
DSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPHPTGERYCVN
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCEEEEC
SASLRFTDGENGEEING
CCEEEECCCCCCCCCCC
>Mature Secondary Structure 
ANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKY
CCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCC
DSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPHPTGERYCVN
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCEEEEC
SASLRFTDGENGEEING
CCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA