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The map label for this gene is dmsB [H]

Identifier: 218551401

GI number: 218551401

Start: 4291978

End: 4292604

Strand: Direct

Name: dmsB [H]

Synonym: EFER_4182

Alternate gene names: 218551401

Gene position: 4291978-4292604 (Clockwise)

Preceding gene: 218551400

Following gene: 218551402

Centisome position: 93.53

GC content: 51.36

Gene sequence:

>627_bases
ATGAAACAGTATGGTTTTTACGTTGACTCCTCGCGTTGCTCTGGCTGCAAAACCTGCCAGGTAAGCTGCAAGGATAATAA
AGATTTGGATGTCGGACCGAAGCTGCGCCGCGTGTATGAATATGGTGGCGGTAGCTGGGTGAAAGAAGGTGAAAGCTGGC
ACAACAATACCTTCACTTACTATTTGTCGATTGCCTGCAATCACTGCGATGAACCGACCTGTGTGGCAGGTTGCCCAACC
GGCGCGATGCACAAACGCGAAGAAGATGGCCTGGTGCTGGTGGATGACAGTGTTTGTGTGGGCTGTCGTTACTGCGAAAT
GCGCTGCCCTTATGGTGCACCGCAGTTTGATACACAAGCTAAAGTGATGCGTAAGTGTGATGGTTGCCTTGACCGACTGG
AGAAAAATCTCCCGCCTATTTGTGTTGAGTCCTGTCCACAGCGAGCTTTGGATTTTGGTCCTATCGACGAATTGCGGGCG
AAATATGGCAGCGAAAATGAAATCGCACCGTTACCTGCCGCTTCGTTTACGCATCCTAACCTGATAATTAAACCGCATCC
GCTGGCGCGACCTACGGGCGACAAAGAAGGGGCGATCATGAACATTCGGGAGGTGCGCCATGCATGA

Upstream 100 bases:

>100_bases
ATTAACACGCTGACAACTCACCTGACCTCGCCGCTGGCGAAAGGGAACCCGCAACATACCAACCTTGTTGAAATTAAACG
CGCTTAAGGAGTGATCCACA

Downstream 100 bases:

>100_bases
GTTACCACTGGTCTTTTTCACCGTATTTACCCAGAGCGCAGTGGGGGCGTTTATTCTGCTGCTGATTGGCGGTGCCATGG
GGTTAATTGAGCCACGTCGT

Product: anaerobic reductase chain B

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKQYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWVKEGESWHNNTFTYYLSIACNHCDEPTCVAGCPT
GAMHKREEDGLVLVDDSVCVGCRYCEMRCPYGAPQFDTQAKVMRKCDGCLDRLEKNLPPICVESCPQRALDFGPIDELRA
KYGSENEIAPLPAASFTHPNLIIKPHPLARPTGDKEGAIMNIREVRHA

Sequences:

>Translated_208_residues
MKQYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWVKEGESWHNNTFTYYLSIACNHCDEPTCVAGCPT
GAMHKREEDGLVLVDDSVCVGCRYCEMRCPYGAPQFDTQAKVMRKCDGCLDRLEKNLPPICVESCPQRALDFGPIDELRA
KYGSENEIAPLPAASFTHPNLIIKPHPLARPTGDKEGAIMNIREVRHA
>Mature_208_residues
MKQYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWVKEGESWHNNTFTYYLSIACNHCDEPTCVAGCPT
GAMHKREEDGLVLVDDSVCVGCRYCEMRCPYGAPQFDTQAKVMRKCDGCLDRLEKNLPPICVESCPQRALDFGPIDELRA
KYGSENEIAPLPAASFTHPNLIIKPHPLARPTGDKEGAIMNIREVRHA

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=203, Percent_Identity=60.5911330049261, Blast_Score=271, Evalue=3e-74,
Organism=Escherichia coli, GI1787872, Length=203, Percent_Identity=59.6059113300493, Blast_Score=268, Evalue=2e-73,
Organism=Escherichia coli, GI226510944, Length=156, Percent_Identity=37.1794871794872, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789370, Length=201, Percent_Identity=30.3482587064677, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1787478, Length=162, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787740, Length=125, Percent_Identity=39.2, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787749, Length=182, Percent_Identity=29.6703296703297, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI2367345, Length=156, Percent_Identity=32.6923076923077, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1790326, Length=161, Percent_Identity=29.8136645962733, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI2367245, Length=156, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787963, Length=152, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI87082179, Length=159, Percent_Identity=28.9308176100629, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082114, Length=194, Percent_Identity=24.2268041237113, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI87082180, Length=198, Percent_Identity=26.2626262626263, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 23176; Mature: 23176

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
10.1 %Cys+Met (Translated Protein)
7.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
10.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWVKEGESWHNNTFTY
CCCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEE
YLSIACNHCDEPTCVAGCPTGAMHKREEDGLVLVDDSVCVGCRYCEMRCPYGAPQFDTQA
EEEEEECCCCCCCEEECCCCCCCCCCCCCCEEEEECCEEECEEEEEEECCCCCCCCCHHH
KVMRKCDGCLDRLEKNLPPICVESCPQRALDFGPIDELRAKYGSENEIAPLPAASFTHPN
HHHHHHHHHHHHHHHCCCCHHHHHCHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCE
LIIKPHPLARPTGDKEGAIMNIREVRHA
EEECCCCCCCCCCCCCCCEEEHHHHHCC
>Mature Secondary Structure
MKQYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWVKEGESWHNNTFTY
CCCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEE
YLSIACNHCDEPTCVAGCPTGAMHKREEDGLVLVDDSVCVGCRYCEMRCPYGAPQFDTQA
EEEEEECCCCCCCEEECCCCCCCCCCCCCCEEEEECCEEECEEEEEEECCCCCCCCCHHH
KVMRKCDGCLDRLEKNLPPICVESCPQRALDFGPIDELRAKYGSENEIAPLPAASFTHPN
HHHHHHHHHHHHHHHCCCCHHHHHCHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCE
LIIKPHPLARPTGDKEGAIMNIREVRHA
EEECCCCCCCCCCCCCCCEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]