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The map label for this gene is dctR [H]

Identifier: 218550340

GI number: 218550340

Start: 3104745

End: 3105308

Strand: Direct

Name: dctR [H]

Synonym: EFER_3032

Alternate gene names: 218550340

Gene position: 3104745-3105308 (Clockwise)

Preceding gene: 218550339

Following gene: 218550344

Centisome position: 67.66

GC content: 39.72

Gene sequence:

>564_bases
ATGAGAAAGAATGAACTGCAACAGGAGTCGGTCATGTTTTTGGTTATCACAAAGGACACTGTTTTATTTAATGCTATTAC
ATTTTTGCTCAATAAGAGCCAGGTTGTTCACGTTCAGGATGAAGATGACATTGACTTAGTGTTGCATCAACATTGCCATA
TAATCATTGATACTTTAATGAACAACGTATTTCACTCGGCCATGGCGGAAAAAATCAAACAGCTAAGACCGGAACAGGTC
ATTGTTTTTTCCCCTTTTATTATCAAAAGATGCCTGGGCGATATTCCCGTGACGTTCGTTTTACGCAACATTTCGCTGAT
AGATTTTATGGTACTGGTCAATCGCGGTCTGTGCCCTGCCCCGGAAGCTGACATCATGCTTTCCCGTAAGCAACATCAGG
TGTTGAGTTATATTGCACAGCAGATGCAAACAGAAGATATTCTGCAGAAAATGCAGATTTCACTCAAAACATTCTACTGT
CATAAACATAGCGTGATGATGATCCTGAATTTAAGAAGAATTACGGAGCTGATAAAGTACCCGCACGTGAGCTATCTTAT
TTAA

Upstream 100 bases:

>100_bases
ACATGTTTGTCATTAGACTCAACGGATACCTCATCAGGTATCCGTTTTTAGATAAAAATGCCAAAGAGGATCTAAGCACA
ATTTAAAAAATTAACCGCAA

Downstream 100 bases:

>100_bases
AAAAAAGGGAGTGGCCTATGCCACGCCCAAATCATTAACTTCAACTGTCGTAATAAGCTGCAAGGGAACACTATCAACTG
ATCGAAACACTTTGCACGCC

Product: HTH-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MRKNELQQESVMFLVITKDTVLFNAITFLLNKSQVVHVQDEDDIDLVLHQHCHIIIDTLMNNVFHSAMAEKIKQLRPEQV
IVFSPFIIKRCLGDIPVTFVLRNISLIDFMVLVNRGLCPAPEADIMLSRKQHQVLSYIAQQMQTEDILQKMQISLKTFYC
HKHSVMMILNLRRITELIKYPHVSYLI

Sequences:

>Translated_187_residues
MRKNELQQESVMFLVITKDTVLFNAITFLLNKSQVVHVQDEDDIDLVLHQHCHIIIDTLMNNVFHSAMAEKIKQLRPEQV
IVFSPFIIKRCLGDIPVTFVLRNISLIDFMVLVNRGLCPAPEADIMLSRKQHQVLSYIAQQMQTEDILQKMQISLKTFYC
HKHSVMMILNLRRITELIKYPHVSYLI
>Mature_187_residues
MRKNELQQESVMFLVITKDTVLFNAITFLLNKSQVVHVQDEDDIDLVLHQHCHIIIDTLMNNVFHSAMAEKIKQLRPEQV
IVFSPFIIKRCLGDIPVTFVLRNISLIDFMVLVNRGLCPAPEADIMLSRKQHQVLSYIAQQMQTEDILQKMQISLKTFYC
HKHSVMMILNLRRITELIKYPHVSYLI

Specific function: May act as a transcriptional regulator of dctA. Could be involved in the regulation of the genes coding for the type III secretion system in enterohaemorragic strains [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789923, Length=176, Percent_Identity=61.3636363636364, Blast_Score=235, Evalue=1e-63,
Organism=Escherichia coli, GI1789928, Length=175, Percent_Identity=22.8571428571429, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 21858; Mature: 21858

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNELQQESVMFLVITKDTVLFNAITFLLNKSQVVHVQDEDDIDLVLHQHCHIIIDTLM
CCCCHHCCCCEEEEEEECHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
NNVFHSAMAEKIKQLRPEQVIVFSPFIIKRCLGDIPVTFVLRNISLIDFMVLVNRGLCPA
HHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PEADIMLSRKQHQVLSYIAQQMQTEDILQKMQISLKTFYCHKHSVMMILNLRRITELIKY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
PHVSYLI
CCCHHCC
>Mature Secondary Structure
MRKNELQQESVMFLVITKDTVLFNAITFLLNKSQVVHVQDEDDIDLVLHQHCHIIIDTLM
CCCCHHCCCCEEEEEEECHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
NNVFHSAMAEKIKQLRPEQVIVFSPFIIKRCLGDIPVTFVLRNISLIDFMVLVNRGLCPA
HHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PEADIMLSRKQHQVLSYIAQQMQTEDILQKMQISLKTFYCHKHSVMMILNLRRITELIKY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
PHVSYLI
CCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]