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The map label for this gene is trxA [H]

Identifier: 218550328

GI number: 218550328

Start: 3089485

End: 3089808

Strand: Reverse

Name: trxA [H]

Synonym: EFER_3020

Alternate gene names: 218550328

Gene position: 3089808-3089485 (Counterclockwise)

Preceding gene: 218550329

Following gene: 218550327

Centisome position: 67.33

GC content: 52.16

Gene sequence:

>324_bases
ATGAAGGAACTGAATAAAGATAATTTTGACGATGCAATCGCCAGTGGTGTGGTGTTGGTTGATTTCTGGAGCGAAAGCTG
TGAACGCTGCAAAGAGTTAATGCCGGATGTCCATCAGCTTTCGGAGGACTACAGCGGCAAAGTGGATTTTTGTAGCCTCA
ATATTCAGGGCAACCGCCGTCTGGCGATGGCGCAAAAGGTGATGGGCCTGCCTTCGATTGTTATCTGGCGTAATGGCGAG
CGGATGACCCATCTTAGCGGCGAGTCGCTCGCTGCCGATGATATTCGTCAGGCGCTTGATGCCGTTCTTGCAGGCGCGGC
GTAA

Upstream 100 bases:

>100_bases
AATTGCCTACGTTGCTGTGCCTTGAGCATGGTGGCGAAATGTGCCGAATGACTAAACCTGCATTTAACTCAATTGATCTC
GTCCTGGAGGAACTCACCGT

Downstream 100 bases:

>100_bases
CCCTTTTTTCAACAAAGGAGAGAGCTATGGATCTCAGAAGTAAAAAAATCATCATCCTTGGTGACAGGGATGGTGTCCCC
GGCCCGGCAATTGAAACTTG

Product: thioredoxin (TRX)

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MKELNKDNFDDAIASGVVLVDFWSESCERCKELMPDVHQLSEDYSGKVDFCSLNIQGNRRLAMAQKVMGLPSIVIWRNGE
RMTHLSGESLAADDIRQALDAVLAGAA

Sequences:

>Translated_107_residues
MKELNKDNFDDAIASGVVLVDFWSESCERCKELMPDVHQLSEDYSGKVDFCSLNIQGNRRLAMAQKVMGLPSIVIWRNGE
RMTHLSGESLAADDIRQALDAVLAGAA
>Mature_107_residues
MKELNKDNFDDAIASGVVLVDFWSESCERCKELMPDVHQLSEDYSGKVDFCSLNIQGNRRLAMAQKVMGLPSIVIWRNGE
RMTHLSGESLAADDIRQALDAVLAGAA

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=104, Percent_Identity=34.6153846153846, Blast_Score=70, Evalue=3e-14,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11815; Mature: 11815

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELNKDNFDDAIASGVVLVDFWSESCERCKELMPDVHQLSEDYSGKVDFCSLNIQGNRR
CCCCCCCCCHHHHHCCEEEEHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEEEECCCCH
LAMAQKVMGLPSIVIWRNGERMTHLSGESLAADDIRQALDAVLAGAA
HHHHHHHHCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKELNKDNFDDAIASGVVLVDFWSESCERCKELMPDVHQLSEDYSGKVDFCSLNIQGNRR
CCCCCCCCCHHHHHCCEEEEHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEEEECCCCH
LAMAQKVMGLPSIVIWRNGERMTHLSGESLAADDIRQALDAVLAGAA
HHHHHHHHCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11271425; 9534247 [H]