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The map label for this gene is grdA [H]

Identifier: 218550327

GI number: 218550327

Start: 3089330

End: 3089458

Strand: Reverse

Name: grdA [H]

Synonym: EFER_3019

Alternate gene names: 218550327

Gene position: 3089458-3089330 (Counterclockwise)

Preceding gene: 218550328

Following gene: 218550326

Centisome position: 67.33

GC content: 51.16

Gene sequence:

>129_bases
ATGGATCTCAGAAGTAAAAAAATCATCATCCTTGGTGACAGGGATGGTGTCCCCGGCCCGGCAATTGAAACTTGCGTGCG
TTCTGCCGGTGCTGAGGTGGTGTTTAGTACGACCGAGTGCTTTGTCTGA

Upstream 100 bases:

>100_bases
ATCTTAGCGGCGAGTCGCTCGCTGCCGATGATATTCGTCAGGCGCTTGATGCCGTTCTTGCAGGCGCGGCGTAACCCTTT
TTTCAACAAAGGAGAGAGCT

Downstream 100 bases:

>100_bases
ACAAGCGCCGGAGCGATGGACCTGGAAAATCAGCGCCGTGTTCTCGCACTGTCAGAAAAATATCCACCGCAAGATCTGAT
TGTGATCCTCGGTGGTTCAG

Product: glycine/sarcosine/betaine reductase complex component A

Products: NA

Alternate protein names: Selenoprotein PA; Thioredoxin reductase complex selenoprotein A [H]

Number of amino acids: Translated: 42; Mature: 42

Protein sequence:

>42_residues
MDLRSKKIIILGDRDGVPGPAIETCVRSAGAEVVFSTTECFV

Sequences:

>Translated_42_residues
MDLRSKKIIILGDRDGVPGPAIETCVRSAGAEVVFSTTECFV
>Mature_42_residues
MDLRSKKIIILGDRDGVPGPAIETCVRSAGAEVVFSTTECFV

Specific function: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a c

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grdA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006812 [H]

Pfam domain/function: PF04723 GRDA [H]

EC number: =1.21.4.2; =1.21.4.3; =1.21.4.4 [H]

Molecular weight: Translated: 4482; Mature: 4482

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRSKKIIILGDRDGVPGPAIETCVRSAGAEVVFSTTECFV
CCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEECCEECC
>Mature Secondary Structure
MDLRSKKIIILGDRDGVPGPAIETCVRSAGAEVVFSTTECFV
CCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEECCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA