Click here to switch to the map view.

The map label for this gene is grdA1 [H]

Identifier: 218550326

GI number: 218550326

Start: 3088985

End: 3089314

Strand: Reverse

Name: grdA1 [H]

Synonym: EFER_3018

Alternate gene names: 218550326

Gene position: 3089314-3088985 (Counterclockwise)

Preceding gene: 218550327

Following gene: 218550325

Centisome position: 67.32

GC content: 51.21

Gene sequence:

>330_bases
ATGGACCTGGAAAATCAGCGCCGTGTTCTCGCACTGTCAGAAAAATATCCACCGCAAGATCTGATTGTGATCCTCGGTGG
TTCAGAAGCAGAAGCTTCTGGTCTGGCATGTGAAACCGTAACAAACGGCGATCCGACTTTTGCAGGCCCTCTGGCGGGAG
TCCAGTTGGGACTCCAGTGTTACCACATAGTGGAAGATGAAGTGAAGCAGGCCGTTGATACCGACGTGTATCAGGAGCAG
GTGGGGATGATGGAGATGGTGCTTGATGTCGACGCTATTTCCCGTGAAGTCCGTCAGTACAGGGAAGAATACTGTCACTA
CCTGAGTTAA

Upstream 100 bases:

>100_bases
TGGTGTCCCCGGCCCGGCAATTGAAACTTGCGTGCGTTCTGCCGGTGCTGAGGTGGTGTTTAGTACGACCGAGTGCTTTG
TCTGAACAAGCGCCGGAGCG

Downstream 100 bases:

>100_bases
CAGGAGGCTCTCCGGCTTCAGTGCCGGAGACCACTTCGGGAGGAATTATGGGAAATGCAGTGATACGACAGGCAGGCTAT
ATCCTGGCGCATACGCCGGA

Product: glycine/sarcosine/betaine reductase complex protein A

Products: NA

Alternate protein names: Selenoprotein PA 1; Thioredoxin reductase complex selenoprotein A 1 [H]

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MDLENQRRVLALSEKYPPQDLIVILGGSEAEASGLACETVTNGDPTFAGPLAGVQLGLQCYHIVEDEVKQAVDTDVYQEQ
VGMMEMVLDVDAISREVRQYREEYCHYLS

Sequences:

>Translated_109_residues
MDLENQRRVLALSEKYPPQDLIVILGGSEAEASGLACETVTNGDPTFAGPLAGVQLGLQCYHIVEDEVKQAVDTDVYQEQ
VGMMEMVLDVDAISREVRQYREEYCHYLS
>Mature_109_residues
MDLENQRRVLALSEKYPPQDLIVILGGSEAEASGLACETVTNGDPTFAGPLAGVQLGLQCYHIVEDEVKQAVDTDVYQEQ
VGMMEMVLDVDAISREVRQYREEYCHYLS

Specific function: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a c

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grdA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006812 [H]

Pfam domain/function: PF04723 GRDA [H]

EC number: =1.21.4.2; =1.21.4.3; =1.21.4.4 [H]

Molecular weight: Translated: 12154; Mature: 12154

Theoretical pI: Translated: 3.96; Mature: 3.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLENQRRVLALSEKYPPQDLIVILGGSEAEASGLACETVTNGDPTFAGPLAGVQLGLQC
CCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
YHIVEDEVKQAVDTDVYQEQVGMMEMVLDVDAISREVRQYREEYCHYLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLENQRRVLALSEKYPPQDLIVILGGSEAEASGLACETVTNGDPTFAGPLAGVQLGLQC
CCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
YHIVEDEVKQAVDTDVYQEQVGMMEMVLDVDAISREVRQYREEYCHYLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA