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The map label for this gene is grdC [H]

Identifier: 218550325

GI number: 218550325

Start: 3087405

End: 3088964

Strand: Reverse

Name: grdC [H]

Synonym: EFER_3017

Alternate gene names: 218550325

Gene position: 3088964-3087405 (Counterclockwise)

Preceding gene: 218550326

Following gene: 218550324

Centisome position: 67.32

GC content: 53.59

Gene sequence:

>1560_bases
GTGCCGGAGACCACTTCGGGAGGAATTATGGGAAATGCAGTGATACGACAGGCAGGCTATATCCTGGCGCATACGCCGGA
TTTGCTGAAATGGCATGGCTCCGCCATTTTGCAAGCCCGACATAAAAACCCGGATGAACCCTGGCTTTCGGAGATACCCC
GCCATCTACGATCTTTTGACCAGGCGGTAAATTATCCCCCGCATCAGTGCTTTATCGGCAATATCAGCCCTGCAGAACTG
GAGACGCTCCCCAGACCCTGGCTCAACGTCATCCAGGAGGGAGGAACAGTCGGCACATTTGGTGAGATATACAGTGAGTC
AGTGCTGTACGGCATGCTCTGTTTTGTAGACGCCTTTGATCTTACTGTCTGGCAGGAGTCGTTTGTCCAGGATATCCGGG
GAAAACTGGCAGATCATCCTACACTGGCCTCTCGTGGCCTGATGGATAAAGCTGTTACAGCCAGTGAAGATGAACTGGCA
CTGCTGGTGGCTCAGCATGCCGCTCCACTGTGGTATGGCGAGCGCCTGGTCGGGTGTGTTAAAGCGGCACATGACCTCGA
TATCAACCTTAGCGCTCACGTTATGCTGGAGAATTTGGTCACTAAAGCCAGTGCAGTACTGGCTGGTTGGCATATCTCCA
GCGATATGCTGGAGAAGGTGGAATACGTTATCGAGTGCTCGGAAGAGGCAATAGGTGATGTTAACCAGCGTGGCGGCGGT
AACCTTGCGAAAGCTGTCGCAGAAAGCCTGAATTGCCTGCAGGCCACTGGGATCGATATGCGTGGTTTCTGTGCCGGGCC
AGTTCATGCGTTGGTCAATGCGGCGGCACTGGTCAAAAGCGGTGTTTATAAACATGTGCTGGTGCTGGCGGGCGGTTCGG
TTGCCAAGCTGGGGATGAACGGACGGGATCACATTCGCCAGGGCTTACCACTGATGGAAGATGTCCTCGGCGGTTTTGCT
CTGCTAATAAGTGAAGATGATGGCGTTAGCCCGGTGATTAATACTCGCGTGGTGGGACGGCACACTGTGGGAACGGGGGC
GTCACCACAGGCAGTAATGGGAGCGTTAATCTCACAACCATTAAAAGCGGTAGGAATGACCACGGCCGATGTCGATAAAT
ATAGCGCCGAACTGCAAAACCCGGAAATCACTCAACCTGCAGGCGCAGGTAACGTACCGGAATCTAACTACAAAATGATT
GCGGCACTCAGTGTAATGGAAGGGTGGCTTGAGCGTAGCCAAATCAACGAGTTTGTGGCACGTCACGGGATGCCTGGCTT
TGCGCCAACACAAGGGCATATTCCTTCTGGCGTTCCGTTTATTGGTCATGGCCTTTGCGAAATTGCGGATAACACCATCG
ACAACTTTATGGTGGTTGGTAAGGGAAGCCTGTTCCTTGGGCGGATGACCAGCCAGTTTGATGGCATTAGCGTACTGGTT
GAACGTAATCAGGGCATTGTGGAAGACGTGGTTCTCGACAACCGTGCCGCCGCAGAGTTGCTGGCGGAAGCGATGCGTAA
AGTTGCCGACGAGCTGGAAGCAGGAGGATGGCATGGCTGA

Upstream 100 bases:

>100_bases
TGGAGATGGTGCTTGATGTCGACGCTATTTCCCGTGAAGTCCGTCAGTACAGGGAAGAATACTGTCACTACCTGAGTTAA
CAGGAGGCTCTCCGGCTTCA

Downstream 100 bases:

>100_bases
GCATCCTGTTGCTAAAACACTTCGCGGGCTGGCAGATGCGCTAAGTGGCGCGCCACCACGGCTGAAAATTGCCTTTACTG
CTCTGGGAAGTGAGTTTTCC

Product: glycine/sarcosine/betaine reductase complex component C subunit beta

Products: NA

Alternate protein names: Protein PC beta [H]

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MPETTSGGIMGNAVIRQAGYILAHTPDLLKWHGSAILQARHKNPDEPWLSEIPRHLRSFDQAVNYPPHQCFIGNISPAEL
ETLPRPWLNVIQEGGTVGTFGEIYSESVLYGMLCFVDAFDLTVWQESFVQDIRGKLADHPTLASRGLMDKAVTASEDELA
LLVAQHAAPLWYGERLVGCVKAAHDLDINLSAHVMLENLVTKASAVLAGWHISSDMLEKVEYVIECSEEAIGDVNQRGGG
NLAKAVAESLNCLQATGIDMRGFCAGPVHALVNAAALVKSGVYKHVLVLAGGSVAKLGMNGRDHIRQGLPLMEDVLGGFA
LLISEDDGVSPVINTRVVGRHTVGTGASPQAVMGALISQPLKAVGMTTADVDKYSAELQNPEITQPAGAGNVPESNYKMI
AALSVMEGWLERSQINEFVARHGMPGFAPTQGHIPSGVPFIGHGLCEIADNTIDNFMVVGKGSLFLGRMTSQFDGISVLV
ERNQGIVEDVVLDNRAAAELLAEAMRKVADELEAGGWHG

Sequences:

>Translated_519_residues
MPETTSGGIMGNAVIRQAGYILAHTPDLLKWHGSAILQARHKNPDEPWLSEIPRHLRSFDQAVNYPPHQCFIGNISPAEL
ETLPRPWLNVIQEGGTVGTFGEIYSESVLYGMLCFVDAFDLTVWQESFVQDIRGKLADHPTLASRGLMDKAVTASEDELA
LLVAQHAAPLWYGERLVGCVKAAHDLDINLSAHVMLENLVTKASAVLAGWHISSDMLEKVEYVIECSEEAIGDVNQRGGG
NLAKAVAESLNCLQATGIDMRGFCAGPVHALVNAAALVKSGVYKHVLVLAGGSVAKLGMNGRDHIRQGLPLMEDVLGGFA
LLISEDDGVSPVINTRVVGRHTVGTGASPQAVMGALISQPLKAVGMTTADVDKYSAELQNPEITQPAGAGNVPESNYKMI
AALSVMEGWLERSQINEFVARHGMPGFAPTQGHIPSGVPFIGHGLCEIADNTIDNFMVVGKGSLFLGRMTSQFDGISVLV
ERNQGIVEDVVLDNRAAAELLAEAMRKVADELEAGGWHG
>Mature_518_residues
PETTSGGIMGNAVIRQAGYILAHTPDLLKWHGSAILQARHKNPDEPWLSEIPRHLRSFDQAVNYPPHQCFIGNISPAELE
TLPRPWLNVIQEGGTVGTFGEIYSESVLYGMLCFVDAFDLTVWQESFVQDIRGKLADHPTLASRGLMDKAVTASEDELAL
LVAQHAAPLWYGERLVGCVKAAHDLDINLSAHVMLENLVTKASAVLAGWHISSDMLEKVEYVIECSEEAIGDVNQRGGGN
LAKAVAESLNCLQATGIDMRGFCAGPVHALVNAAALVKSGVYKHVLVLAGGSVAKLGMNGRDHIRQGLPLMEDVLGGFAL
LISEDDGVSPVINTRVVGRHTVGTGASPQAVMGALISQPLKAVGMTTADVDKYSAELQNPEITQPAGAGNVPESNYKMIA
ALSVMEGWLERSQINEFVARHGMPGFAPTQGHIPSGVPFIGHGLCEIADNTIDNFMVVGKGSLFLGRMTSQFDGISVLVE
RNQGIVEDVVLDNRAAAELLAEAMRKVADELEAGGWHG

Specific function: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a c

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR017236
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III [H]

EC number: =1.21.4.2; =1.21.4.3; =1.21.4.4 [H]

Molecular weight: Translated: 55513; Mature: 55382

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETTSGGIMGNAVIRQAGYILAHTPDLLKWHGSAILQARHKNPDEPWLSEIPRHLRSFD
CCCCCCCCCHHHHHHHHCCEEEECCCHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
QAVNYPPHQCFIGNISPAELETLPRPWLNVIQEGGTVGTFGEIYSESVLYGMLCFVDAFD
HHHCCCCCEEEECCCCHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTVWQESFVQDIRGKLADHPTLASRGLMDKAVTASEDELALLVAQHAAPLWYGERLVGCV
HHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
KAAHDLDINLSAHVMLENLVTKASAVLAGWHISSDMLEKVEYVIECSEEAIGDVNQRGGG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHCCCCCCCCC
NLAKAVAESLNCLQATGIDMRGFCAGPVHALVNAAALVKSGVYKHVLVLAGGSVAKLGMN
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCC
GRDHIRQGLPLMEDVLGGFALLISEDDGVSPVINTRVVGRHTVGTGASPQAVMGALISQP
CHHHHHHCCCHHHHHHCCEEEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHH
LKAVGMTTADVDKYSAELQNPEITQPAGAGNVPESNYKMIAALSVMEGWLERSQINEFVA
HHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RHGMPGFAPTQGHIPSGVPFIGHGLCEIADNTIDNFMVVGKGSLFLGRMTSQFDGISVLV
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCEEECHHHCCCCCEEEEE
ERNQGIVEDVVLDNRAAAELLAEAMRKVADELEAGGWHG
ECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PETTSGGIMGNAVIRQAGYILAHTPDLLKWHGSAILQARHKNPDEPWLSEIPRHLRSFD
CCCCCCCCHHHHHHHHCCEEEECCCHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
QAVNYPPHQCFIGNISPAELETLPRPWLNVIQEGGTVGTFGEIYSESVLYGMLCFVDAFD
HHHCCCCCEEEECCCCHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTVWQESFVQDIRGKLADHPTLASRGLMDKAVTASEDELALLVAQHAAPLWYGERLVGCV
HHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
KAAHDLDINLSAHVMLENLVTKASAVLAGWHISSDMLEKVEYVIECSEEAIGDVNQRGGG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHCCCCCCCCC
NLAKAVAESLNCLQATGIDMRGFCAGPVHALVNAAALVKSGVYKHVLVLAGGSVAKLGMN
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCC
GRDHIRQGLPLMEDVLGGFALLISEDDGVSPVINTRVVGRHTVGTGASPQAVMGALISQP
CHHHHHHCCCHHHHHHCCEEEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHH
LKAVGMTTADVDKYSAELQNPEITQPAGAGNVPESNYKMIAALSVMEGWLERSQINEFVA
HHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RHGMPGFAPTQGHIPSGVPFIGHGLCEIADNTIDNFMVVGKGSLFLGRMTSQFDGISVLV
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCEEECHHHCCCCCEEEEE
ERNQGIVEDVVLDNRAAAELLAEAMRKVADELEAGGWHG
ECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8223622; 1587286 [H]