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The map label for this gene is grdD [H]

Identifier: 218550324

GI number: 218550324

Start: 3086285

End: 3087547

Strand: Reverse

Name: grdD [H]

Synonym: EFER_3016

Alternate gene names: 218550324

Gene position: 3087547-3086285 (Counterclockwise)

Preceding gene: 218550325

Following gene: 218550323

Centisome position: 67.29

GC content: 55.27

Gene sequence:

>1263_bases
TTGATGGCATTAGCGTACTGGTTGAACGTAATCAGGGCATTGTGGAAGACGTGGTTCTCGACAACCGTGCCGCCGCAGAG
TTGCTGGCGGAAGCGATGCGTAAAGTTGCCGACGAGCTGGAAGCAGGAGGATGGCATGGCTGAGCATCCTGTTGCTAAAA
CACTTCGCGGGCTGGCAGATGCGCTAAGTGGCGCGCCACCACGGCTGAAAATTGCCTTTACTGCTCTGGGAAGTGAGTTT
TCCACCGATGTACTGCTCAGCGCAGCTGAACAGGTAGCTGACCGATTACTACCGGTCATTATTGGCCCGAAGCCCATCCC
CGGATTTCCCTGGTATCAGGCGGATGAATTGGCGTCGGCGCATCGAATCATGGAGCAACTGTTAGCAGATGGCGAAGTCG
CAGGCGCAGTGACCCTGCACTACAACTTCCCACTTGGTGTTGCCACTGTTGCACAAATCCATTCGATAGCAACCGGTCGG
TCAATGGTGCTGGCCAGTACCACAGGCACCAGCGATGTTCACCGCCCTGCGGCGATGGTGAAAAACGCCATTGCTGGCGT
GGCGATGGCAGAAGCTCTCGGCATTGAGGAACCCCGGGTAGGTATCCTCAATGTGGACGATGCTTCTACTGTTCAACGTC
TGCTGGCGCGACTTAGGGAGGCCGGATTCCCGCTACATTTTGCGCAGTCTTCACGAGCTGATGGCGGAGCGCTGATGCGC
GGTAACGATCTTATTCGTGCCACATCTGACGTGCTGGTTTGCGACACGCTCACCGGAAACTTGCTGATTAAGCTCTTCAG
TGCGGGTCTTAGCGGCGGCGAAATGGAAACAATGGGCAGCGGCTATGGCATTGGTCTTGGGCCAGATCAAAAAGCGATCA
TTGGCATTATTTCGCGTGCCAGCGGCCCGGCGACCATTTCCCAGGCACTCTGTTTTTGCGCTCAGATGGCAAGAAACGAT
CTGATGCGTCACTGGCAGAAATGTTGGCAGCTTGCCAGTAGTTGCGGGATCGAAGAGATCGTCCATCAACGTACGCCTTC
TGCCGGGCCGTCGACAACTATCGCAGTATCTGCGCCACCAAAAACCGTACTGGACGATGAGATCCACGGCATCGACATTC
TCCGCCTGGAGGAGGCCTGCCAGCATTTGTGGCGACATGGGATCTACGCTGAAACCGGCATGGGCTGTACCGGTCCGGTG
TTGATGATTAATCGTCAACAACGTGCAGATGCTGATCAGCATCTGAAATCGTTTTTGAGTTAA

Upstream 100 bases:

>100_bases
TTTATTGGTCATGGCCTTTGCGAAATTGCGGATAACACCATCGACAACTTTATGGTGGTTGGTAAGGGAAGCCTGTTCCT
TGGGCGGATGACCAGCCAGT

Downstream 100 bases:

>100_bases
GGAGCCAGCCATGAAACTGGAACTTGGCACTATTCAGATCAAGCAGTTCACTTTTGCAGAAAAAACATCACTGGCAGGCG
GACATTTGCAGCTCTGTCAG

Product: glycine/sarcosine/betaine reductase complex component C subunit alpha

Products: NA

Alternate protein names: Protein PC alpha [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MMALAYWLNVIRALWKTWFSTTVPPQSCWRKRCVKLPTSWKQEDGMAEHPVAKTLRGLADALSGAPPRLKIAFTALGSEF
STDVLLSAAEQVADRLLPVIIGPKPIPGFPWYQADELASAHRIMEQLLADGEVAGAVTLHYNFPLGVATVAQIHSIATGR
SMVLASTTGTSDVHRPAAMVKNAIAGVAMAEALGIEEPRVGILNVDDASTVQRLLARLREAGFPLHFAQSSRADGGALMR
GNDLIRATSDVLVCDTLTGNLLIKLFSAGLSGGEMETMGSGYGIGLGPDQKAIIGIISRASGPATISQALCFCAQMARND
LMRHWQKCWQLASSCGIEEIVHQRTPSAGPSTTIAVSAPPKTVLDDEIHGIDILRLEEACQHLWRHGIYAETGMGCTGPV
LMINRQQRADADQHLKSFLS

Sequences:

>Translated_420_residues
MMALAYWLNVIRALWKTWFSTTVPPQSCWRKRCVKLPTSWKQEDGMAEHPVAKTLRGLADALSGAPPRLKIAFTALGSEF
STDVLLSAAEQVADRLLPVIIGPKPIPGFPWYQADELASAHRIMEQLLADGEVAGAVTLHYNFPLGVATVAQIHSIATGR
SMVLASTTGTSDVHRPAAMVKNAIAGVAMAEALGIEEPRVGILNVDDASTVQRLLARLREAGFPLHFAQSSRADGGALMR
GNDLIRATSDVLVCDTLTGNLLIKLFSAGLSGGEMETMGSGYGIGLGPDQKAIIGIISRASGPATISQALCFCAQMARND
LMRHWQKCWQLASSCGIEEIVHQRTPSAGPSTTIAVSAPPKTVLDDEIHGIDILRLEEACQHLWRHGIYAETGMGCTGPV
LMINRQQRADADQHLKSFLS
>Mature_420_residues
MMALAYWLNVIRALWKTWFSTTVPPQSCWRKRCVKLPTSWKQEDGMAEHPVAKTLRGLADALSGAPPRLKIAFTALGSEF
STDVLLSAAEQVADRLLPVIIGPKPIPGFPWYQADELASAHRIMEQLLADGEVAGAVTLHYNFPLGVATVAQIHSIATGR
SMVLASTTGTSDVHRPAAMVKNAIAGVAMAEALGIEEPRVGILNVDDASTVQRLLARLREAGFPLHFAQSSRADGGALMR
GNDLIRATSDVLVCDTLTGNLLIKLFSAGLSGGEMETMGSGYGIGLGPDQKAIIGIISRASGPATISQALCFCAQMARND
LMRHWQKCWQLASSCGIEEIVHQRTPSAGPSTTIAVSAPPKTVLDDEIHGIDILRLEEACQHLWRHGIYAETGMGCTGPV
LMINRQQRADADQHLKSFLS

Specific function: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a c

COG id: COG0416

COG function: function code I; Fatty acid/phospholipid biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003664
- InterPro:   IPR012116 [H]

Pfam domain/function: PF02504 FA_synthesis [H]

EC number: =1.21.4.2; =1.21.4.3; =1.21.4.4 [H]

Molecular weight: Translated: 45135; Mature: 45135

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMALAYWLNVIRALWKTWFSTTVPPQSCWRKRCVKLPTSWKQEDGMAEHPVAKTLRGLAD
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ALSGAPPRLKIAFTALGSEFSTDVLLSAAEQVADRLLPVIIGPKPIPGFPWYQADELASA
HHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHH
HRIMEQLLADGEVAGAVTLHYNFPLGVATVAQIHSIATGRSMVLASTTGTSDVHRPAAMV
HHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
KNAIAGVAMAEALGIEEPRVGILNVDDASTVQRLLARLREAGFPLHFAQSSRADGGALMR
HHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEE
GNDLIRATSDVLVCDTLTGNLLIKLFSAGLSGGEMETMGSGYGIGLGPDQKAIIGIISRA
CCCHHEECCCEEEEECCHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHCC
SGPATISQALCFCAQMARNDLMRHWQKCWQLASSCGIEEIVHQRTPSAGPSTTIAVSAPP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEECCC
KTVLDDEIHGIDILRLEEACQHLWRHGIYAETGMGCTGPVLMINRQQRADADQHLKSFLS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHCCHHHHHHHHHC
>Mature Secondary Structure
MMALAYWLNVIRALWKTWFSTTVPPQSCWRKRCVKLPTSWKQEDGMAEHPVAKTLRGLAD
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ALSGAPPRLKIAFTALGSEFSTDVLLSAAEQVADRLLPVIIGPKPIPGFPWYQADELASA
HHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHH
HRIMEQLLADGEVAGAVTLHYNFPLGVATVAQIHSIATGRSMVLASTTGTSDVHRPAAMV
HHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
KNAIAGVAMAEALGIEEPRVGILNVDDASTVQRLLARLREAGFPLHFAQSSRADGGALMR
HHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEE
GNDLIRATSDVLVCDTLTGNLLIKLFSAGLSGGEMETMGSGYGIGLGPDQKAIIGIISRA
CCCHHEECCCEEEEECCHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHCC
SGPATISQALCFCAQMARNDLMRHWQKCWQLASSCGIEEIVHQRTPSAGPSTTIAVSAPP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEECCC
KTVLDDEIHGIDILRLEEACQHLWRHGIYAETGMGCTGPVLMINRQQRADADQHLKSFLS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11737196; 1587286 [H]