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The map label for this gene is epsG [H]

Identifier: 218550226

GI number: 218550226

Start: 2987727

End: 2988209

Strand: Direct

Name: epsG [H]

Synonym: EFER_2918

Alternate gene names: 218550226

Gene position: 2987727-2988209 (Clockwise)

Preceding gene: 218550225

Following gene: 218550227

Centisome position: 65.11

GC content: 50.52

Gene sequence:

>483_bases
TTGGAATGTAATTTACGGAGTTATCACATGAATTCGTTATCCCGTACACAAAAACCACGGGCAGGTTTTACCCTGCTGGA
AGTGATGGTGGTGATTGTTATTCTTGGCGTCCTGGCAAGTCTGGTGGTGCCTAACCTTTTGGGCAACAAAGAGAAAGCAG
ATCGGCAAAAAGCCATCAGCGATATCGTGGCGCTGGAGAACGCGCTGGATATGTATCGACTGGATAACGGGCGTTATCCG
ACCACCGAACAGGGGCTTGAGGCGCTGATCCAGCAACCGGCCAATATGGCGGATTCCCGTAACTACCGTCCTGGTGGATA
CATCAAACGGCTGCCAAAGGATCCGTGGGGCAATGATTATCAGTATCTCAGCCCGGGTGAAAAAGGACTGTTTGATGTTT
ACACCTTAGGGGCGGATGGTCAGGAAAACGGGGAAGGTGCTGGCGCAGATATCGGTAACTGGAATTTGCAGGAGTTTCAG
TAA

Upstream 100 bases:

>100_bases
TTAGGGCTGTTTGAACCGGCGCTGGTGGTAATGATGGCGGGCGTGGTGCTGTTTATCGTCATCGCCATCCTCGAGCCGAT
GCTGCAACTGAACAATATGG

Downstream 100 bases:

>100_bases
TCAGTGCCCAAACGCGGATTCACTCTTCTGGAAATCATGCTGGTGATTTTCCTTATCGGCCTTGCCAGTGCGGGCGTGGT
ACAGACTTTTGCGAGCCGTT

Product: general secretion pathway protein G

Products: NA

Alternate protein names: Cholera toxin secretion protein epsG [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MECNLRSYHMNSLSRTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKADRQKAISDIVALENALDMYRLDNGRYP
TTEQGLEALIQQPANMADSRNYRPGGYIKRLPKDPWGNDYQYLSPGEKGLFDVYTLGADGQENGEGAGADIGNWNLQEFQ

Sequences:

>Translated_160_residues
MECNLRSYHMNSLSRTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKADRQKAISDIVALENALDMYRLDNGRYP
TTEQGLEALIQQPANMADSRNYRPGGYIKRLPKDPWGNDYQYLSPGEKGLFDVYTLGADGQENGEGAGADIGNWNLQEFQ
>Mature_160_residues
MECNLRSYHMNSLSRTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKADRQKAISDIVALENALDMYRLDNGRYP
TTEQGLEALIQQPANMADSRNYRPGGYIKRLPKDPWGNDYQYLSPGEKGLFDVYTLGADGQENGEGAGADIGNWNLQEFQ

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for secretion of cholera toxin through the outer membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP G family [H]

Homologues:

Organism=Escherichia coli, GI1789725, Length=144, Percent_Identity=62.5, Blast_Score=161, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000983
- InterPro:   IPR012902
- InterPro:   IPR001120
- InterPro:   IPR013545
- InterPro:   IPR010054 [H]

Pfam domain/function: PF08334 GSPII_G; PF07963 N_methyl [H]

EC number: NA

Molecular weight: Translated: 17793; Mature: 17793

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECNLRSYHMNSLSRTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKADRQKAIS
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DIVALENALDMYRLDNGRYPTTEQGLEALIQQPANMADSRNYRPGGYIKRLPKDPWGNDY
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCHHHHCCCCCCCCCCC
QYLSPGEKGLFDVYTLGADGQENGEGAGADIGNWNLQEFQ
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MECNLRSYHMNSLSRTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKADRQKAIS
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DIVALENALDMYRLDNGRYPTTEQGLEALIQQPANMADSRNYRPGGYIKRLPKDPWGNDY
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCHHHHCCCCCCCCCCC
QYLSPGEKGLFDVYTLGADGQENGEGAGADIGNWNLQEFQ
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]