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The map label for this gene is yeeO [H]

Identifier: 218549322

GI number: 218549322

Start: 2041421

End: 2042857

Strand: Reverse

Name: yeeO [H]

Synonym: EFER_1985

Alternate gene names: 218549322

Gene position: 2042857-2041421 (Counterclockwise)

Preceding gene: 218549337

Following gene: 218549321

Centisome position: 44.52

GC content: 49.48

Gene sequence:

>1437_bases
TTGAATATCACTTCTGCTGTACGCCATGCCGTAACCCGCACGACCTGGTACGCCAAACGTAAGAGTTATAAAGTTCTCTT
CTGGCGTGAAATTACACCGCTTGCTGTGCCCATCTTTCTGGAAAACGGTTGTGTGCTGTTAATGGGGGTATTGAGCACGT
TCCTGGTGAGCTGGCTGGGTAAGGATGCAATGGCGGGAGTGGGCCTTGCAGACAGCTTTAACATGGTGATTATGGCTTTT
TTTGCTGCTATTGACCTGGGTACGACGGTGGTAGTGGCATTTAGCCTCGGGAAACGTAACCGACGACGCGCCAGAACGGC
AACGAGGCAGTCGCTGGTCATTATGACGTTATTTGCCATATTGTTGGCGGCGGTGATTCATTACTTTGGTGAGCAGATCA
TCAATATTGTTGCCGGAGAGGCTACAGAACACGTCAAAGCGCTGGCGTTGATCTATCTGGAGTTGACGGTACTGAGTTAT
CCGGCGGCAGCCATAGCGCTAATTGGTAGTGGTGCGTTGCGAGGGGCCGGTAACACGAAAATTCCGCTGCTCATTAACGG
TGGCATGAATATTCTCAATATCATCATTAGCAGCATACTTATTTATGGCATTTTTTCATGGCAAGGCCTTGGTTTTGAAG
GGGCGGGCCTGGGGCTGACAATCTCCCGCTATATTGGAGCTGTTGCCATTATATGGGTGTTGATGATCGGTTTTAATCCG
GCGCTGCGTATCACCTTGAAAAGCTATTTCAGGCCACTGAATTTTTCTGTTATTTGGGAAGTGATGGGAATAGGTATCCC
GGCGAGTGTCGAATCAGTTCTCTTTACCAGTGGACGTCTGTTAACACAAATGTTTGTTGCCGGGATGGGAACCAGTGTTA
TTGCCGGTAATTTTATCGCCTTTTCAATTGCTGCACTTATCAACCTTCCTGGTAATGCGTTGGCCTCGGCCTCAACAATT
ATTACCGGACGGCGATTAGGTAACGGTCAAATTGCTCAGGCTGCAATTCAGCTGCGTCATGTGTTCTGGTTATCAACCAT
TGGTCTGACCGCAATAGCCTGGCTGAGCGCACCATTTGCCAGTCTGATGGCTTCCTTTTATACCCACGATCCTGAAGTTA
TTCATGTGGTGGTGGTCCTCGTTTGGCTCAATGCGGCGTTTATGCCAATCTGGACAGCGGCCTGGGTTGTGCCTGCCGGG
TTTAAAGGCGCACGGGATGCACGCTATGCAATGTGGGTATCAATGTTAGGGATGTGGGGATGCCGGGTCGTGGTGGGCTA
TACGCTGGGTATTGTTCTTGGCTGGGGCGTTGTGGGTGTCTGGATGGGAATGTTCTCAGACTGGGCAGTCCGGGCAATTC
TCTTTTATCGTCGGATGAAAACCGGTAAATGGTTATGGAAATATCCCAGGACACACCTTGAAAAGGTGGAAAAATAA

Upstream 100 bases:

>100_bases
TTGCATTTCCAGACAATTTTAACGGGAAATAATTTTGCAGGATTGTCGATTCTCCCTCATCATTTGAAATGCGGTTTCAC
ATTTTTCTTTAAGGTCTGCT

Downstream 100 bases:

>100_bases
GCGTTTGTGGCGCAATTTAATGCGAAATGAGGAATATTTCAGCAAACGATCAGGAATATGAATTCAGCCTTTGACATTGC
ATATCGTCATCGTTAATATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MNITSAVRHAVTRTTWYAKRKSYKVLFWREITPLAVPIFLENGCVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAF
FAAIDLGTTVVVAFSLGKRNRRRARTATRQSLVIMTLFAILLAAVIHYFGEQIINIVAGEATEHVKALALIYLELTVLSY
PAAAIALIGSGALRGAGNTKIPLLINGGMNILNIIISSILIYGIFSWQGLGFEGAGLGLTISRYIGAVAIIWVLMIGFNP
ALRITLKSYFRPLNFSVIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGNALASASTI
ITGRRLGNGQIAQAAIQLRHVFWLSTIGLTAIAWLSAPFASLMASFYTHDPEVIHVVVVLVWLNAAFMPIWTAAWVVPAG
FKGARDARYAMWVSMLGMWGCRVVVGYTLGIVLGWGVVGVWMGMFSDWAVRAILFYRRMKTGKWLWKYPRTHLEKVEK

Sequences:

>Translated_478_residues
MNITSAVRHAVTRTTWYAKRKSYKVLFWREITPLAVPIFLENGCVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAF
FAAIDLGTTVVVAFSLGKRNRRRARTATRQSLVIMTLFAILLAAVIHYFGEQIINIVAGEATEHVKALALIYLELTVLSY
PAAAIALIGSGALRGAGNTKIPLLINGGMNILNIIISSILIYGIFSWQGLGFEGAGLGLTISRYIGAVAIIWVLMIGFNP
ALRITLKSYFRPLNFSVIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGNALASASTI
ITGRRLGNGQIAQAAIQLRHVFWLSTIGLTAIAWLSAPFASLMASFYTHDPEVIHVVVVLVWLNAAFMPIWTAAWVVPAG
FKGARDARYAMWVSMLGMWGCRVVVGYTLGIVLGWGVVGVWMGMFSDWAVRAILFYRRMKTGKWLWKYPRTHLEKVEK
>Mature_478_residues
MNITSAVRHAVTRTTWYAKRKSYKVLFWREITPLAVPIFLENGCVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAF
FAAIDLGTTVVVAFSLGKRNRRRARTATRQSLVIMTLFAILLAAVIHYFGEQIINIVAGEATEHVKALALIYLELTVLSY
PAAAIALIGSGALRGAGNTKIPLLINGGMNILNIIISSILIYGIFSWQGLGFEGAGLGLTISRYIGAVAIIWVLMIGFNP
ALRITLKSYFRPLNFSVIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGNALASASTI
ITGRRLGNGQIAQAAIQLRHVFWLSTIGLTAIAWLSAPFASLMASFYTHDPEVIHVVVVLVWLNAAFMPIWTAAWVVPAG
FKGARDARYAMWVSMLGMWGCRVVVGYTLGIVLGWGVVGVWMGMFSDWAVRAILFYRRMKTGKWLWKYPRTHLEKVEK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=478, Percent_Identity=86.4016736401674, Blast_Score=831, Evalue=0.0,
Organism=Escherichia coli, GI48994890, Length=462, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 52207; Mature: 52207

Theoretical pI: Translated: 10.78; Mature: 10.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITSAVRHAVTRTTWYAKRKSYKVLFWREITPLAVPIFLENGCVLLMGVLSTFLVSWLG
CCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHC
KDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRNRRRARTATRQSLVIMTLFAI
CHHHCCCCCCCHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LLAAVIHYFGEQIINIVAGEATEHVKALALIYLELTVLSYPAAAIALIGSGALRGAGNTK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCE
IPLLINGGMNILNIIISSILIYGIFSWQGLGFEGAGLGLTISRYIGAVAIIWVLMIGFNP
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCC
ALRITLKSYFRPLNFSVIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIA
HHEEEHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHH
FSIAALINLPGNALASASTIITGRRLGNGQIAQAAIQLRHVFWLSTIGLTAIAWLSAPFA
HHHHHHHCCCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLMASFYTHDPEVIHVVVVLVWLNAAFMPIWTAAWVVPAGFKGARDARYAMWVSMLGMWG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
CRVVVGYTLGIVLGWGVVGVWMGMFSDWAVRAILFYRRMKTGKWLWKYPRTHLEKVEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHCCC
>Mature Secondary Structure
MNITSAVRHAVTRTTWYAKRKSYKVLFWREITPLAVPIFLENGCVLLMGVLSTFLVSWLG
CCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHC
KDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRNRRRARTATRQSLVIMTLFAI
CHHHCCCCCCCHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LLAAVIHYFGEQIINIVAGEATEHVKALALIYLELTVLSYPAAAIALIGSGALRGAGNTK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCE
IPLLINGGMNILNIIISSILIYGIFSWQGLGFEGAGLGLTISRYIGAVAIIWVLMIGFNP
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCC
ALRITLKSYFRPLNFSVIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIA
HHEEEHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHH
FSIAALINLPGNALASASTIITGRRLGNGQIAQAAIQLRHVFWLSTIGLTAIAWLSAPFA
HHHHHHHCCCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLMASFYTHDPEVIHVVVVLVWLNAAFMPIWTAAWVVPAGFKGARDARYAMWVSMLGMWG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
CRVVVGYTLGIVLGWGVVGVWMGMFSDWAVRAILFYRRMKTGKWLWKYPRTHLEKVEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]