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The map label for this gene is sapC [H]

Identifier: 218549014

GI number: 218549014

Start: 1708419

End: 1709309

Strand: Direct

Name: sapC [H]

Synonym: EFER_1662

Alternate gene names: 218549014

Gene position: 1708419-1709309 (Clockwise)

Preceding gene: 218549013

Following gene: 218549015

Centisome position: 37.23

GC content: 52.19

Gene sequence:

>891_bases
ATGCCTTACGATAGCGTATACAGCGAAAAGCGCCCGCCTGGTACGCTGCGTACAGCCTGGCGCAAATTTTATGCTGATAC
TTCCGCAATGGTCGGTCTGTACGGTTGTGCAGGCCTCGCGATACTGTGTATTTTTGGTGGCTGGTTTGCGCCATACGGCA
TCGATCAGCAATTTCTTGGCTATCAGTTGCTACCACCGTCATGGTCGCGGTATGGCGAAGTCTCTTTCTTTCTGGGTACT
GATGATCTCGGTCGCGATGTTTTAAGTCGTTTACTCAGTGGTGCAGCTCCCACTGTCGGAGGCGCATTTGTCGTCACTCT
GGCTGCAACTCTTTGTGGCCTGGTATTAGGTGTGGTCGCTGGGGCAACTCATGGCTTACGTTCAGCGGTACTCAACCATA
TTCTCGATACCTTGCTGGCGATCCCTTCATTGTTGCTGGCTATTATTGTGGTGGCTTTTGCCGGGCCATCACTCGGTCAT
GCGATGTTTGCTGTCTGGCTGGCACTTTTGCCGCGTATCGTACGCTCGGTTTATAGCCTGGTGCATGATGAACTGGAAAA
AGAGTATGTCATCGCCGCTCGTCTCGATGGCGCAACCACATTGAATATTCTCTGGTTTGCTGTTCTGCCCAACATTACCG
CAGGTCTGGTCACTGAAATTACCCGCGCCCTTTCGATGGCGATTTTGGATATTGCCGCGCTGGGTTTTCTTGATCTCGGC
GCGCAACTCCCCTCACCTGAATGGGGGGCCATGCTTGGCGATGCGCTGGAACTTATTTATGTTGCGCCATGGACCGTTAT
GCTGCCAGGTGCAGCAATTATGATCAGCGTTTTGTTAGTTAACTTACTCGGTGACGGAATACGCCGGGCCATTATTGCGG
GGGTGGAATAA

Upstream 100 bases:

>100_bases
TCTGCCGGTGTAATGGTGTGTGGTTCGCTGGTAATTATTGTTAACGTGATATCTGATATTTTGGGTGCAATGGCTAACCC
GCTTAAACATAAGGAATTTT

Downstream 100 bases:

>100_bases
TGCCGTTACTCGATATCCGCAATTTGACCATCGAATTCAAAACTGGCGATGAATGGGTTAAAGCCGTTGACCGTGTCAGC
ATGACCTTAAATGAAGGTGA

Product: antimicrobial peptide ABC transporter permease

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPYDSVYSEKRPPGTLRTAWRKFYADTSAMVGLYGCAGLAILCIFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGT
DDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVVAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLGH
AMFAVWLALLPRIVRSVYSLVHDELEKEYVIAARLDGATTLNILWFAVLPNITAGLVTEITRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGIRRAIIAGVE

Sequences:

>Translated_296_residues
MPYDSVYSEKRPPGTLRTAWRKFYADTSAMVGLYGCAGLAILCIFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGT
DDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVVAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLGH
AMFAVWLALLPRIVRSVYSLVHDELEKEYVIAARLDGATTLNILWFAVLPNITAGLVTEITRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGIRRAIIAGVE
>Mature_295_residues
PYDSVYSEKRPPGTLRTAWRKFYADTSAMVGLYGCAGLAILCIFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTD
DLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVVAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLGHA
MFAVWLALLPRIVRSVYSLVHDELEKEYVIAARLDGATTLNILWFAVLPNITAGLVTEITRALSMAILDIAALGFLDLGA
QLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGIRRAIIAGVE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=296, Percent_Identity=95.6081081081081, Blast_Score=568, Evalue=1e-163,
Organism=Escherichia coli, GI1789964, Length=288, Percent_Identity=40.9722222222222, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1787054, Length=284, Percent_Identity=34.8591549295775, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1787760, Length=248, Percent_Identity=35.4838709677419, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789889, Length=241, Percent_Identity=31.1203319502075, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787498, Length=280, Percent_Identity=27.1428571428571, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31456; Mature: 31325

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYDSVYSEKRPPGTLRTAWRKFYADTSAMVGLYGCAGLAILCIFGGWFAPYGIDQQFLG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
YQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVVA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLGHAMFAVWLALLPRIVRSVYSL
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VHDELEKEYVIAARLDGATTLNILWFAVLPNITAGLVTEITRALSMAILDIAALGFLDLG
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGIRRAIIAGVE
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PYDSVYSEKRPPGTLRTAWRKFYADTSAMVGLYGCAGLAILCIFGGWFAPYGIDQQFLG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
YQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVVA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLGHAMFAVWLALLPRIVRSVYSL
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VHDELEKEYVIAARLDGATTLNILWFAVLPNITAGLVTEITRALSMAILDIAALGFLDLG
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGIRRAIIAGVE
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]